List of works by Grant R. Drummond

3', 4'-dihydroxyflavonol enhances nitric oxide bioavailability and improves vascular function after ischemia and reperfusion injury in the rat.

scientific article published in December 2003

A flow cytometric method for the analysis of macrophages in the vascular wall

scientific article published on 6 August 2013

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1.

scientific article published on 30 August 2013

Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies

scientific article published in January 2015

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke.

scientific article published on 30 January 2018

Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension

scientific article published on 22 December 2016

Adventitial application of the NADPH oxidase inhibitor apocynin in vivo reduces neointima formation and endothelial dysfunction in rabbits

scientific article published on 19 June 2007

Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke

scientific article published on 30 October 2012

Aldosterone-Induced Hypertension is Sex-Dependent, Mediated by T Cells and Sensitive to GPER Activation

scientific article published on 26 March 2020

Aldosterone-induced oxidative stress and inflammation in the brain are mediated by the endothelial cell mineralocorticoid receptor

scientific article

Amnion epithelial cells - a novel therapy for ischemic stroke?

article published in 2018

Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.

scientific article published on 13 December 2016

Angiotensin (1-7) as a therapy to prevent rupture of intracranial aneurysms?

scientific article published on 01 August 2014

Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction.

scientific article published on 22 February 2014

Antibodies in the pathogenesis of hypertension

scientific article

Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes

scientific article published on 12 July 2006

Antioxidant and nitric oxide-sparing actions of dihydropyridines and ACE inhibitors differ in human endothelial cells.

scientific article published on 10 October 2005

Apamin-sensitive, non-nitric oxide (NO) endothelium-dependent relaxations to bradykinin in the bovine isolated coronary artery: no role for cytochrome P450 and K+.

scientific article

Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia.

scientific article published on 18 February 2010

B2 kinin receptor activation is the predominant mechanism by which trypsin mediates endothelium-dependent relaxation in bovine coronary arteries

scientific article published on 6 May 2008

Bacteriophages in Natural and Artificial Environments

scientific article published on 12 July 2019

Brain immune cell composition and functional outcome after cerebral ischemia: comparison of two mouse strains

scientific article

Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression.

scientific article published on 18 September 2012

C-type natriuretic peptide (CNP) suppresses plasminogen activator inhibitor-1 (PAI-1) in vivo

scientific article published on 25 February 2005

CEACAM1: an adhesion molecule that limits blood-brain barrier damage by neutrophils after stroke

scientific article published in September 2013

Cardiac Tissue Injury and Remodeling Is Dependent Upon MR Regulation of Activation Pathways in Cardiac Tissue Macrophages.

scientific article published on 2 June 2016

Cell-specific mineralocorticoid receptors: future therapeutic targets for stroke?

scientific article published on August 2016

Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome

scientific article

Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species

scientific article published on March 2012

Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation.

scientific article

Chronic angiotensin IV treatment reverses endothelial dysfunction in ApoE-deficient mice

scientific article published on 19 September 2007

Chronic recurrent dehydration associated with periodic water intake exacerbates hypertension and promotes renal damage in male spontaneously hypertensive rats

scientific article published on 22 September 2016

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

scientific article

Deficiency of Prebiotic Fibre and Insufficient Signalling Through Gut Metabolite Sensing Receptors Leads to Cardiovascular Disease

scientific article published on 25 February 2020

Diagnosing and Treating Hypertensive Disorders of Pregnancy? The Answer May Now Be Less BAFF-ling.

scientific article published on 18 September 2017

Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice

scientific article

Differential phenotypes of tissue-infiltrating T cells during angiotensin II-induced hypertension in mice.

scientific article published on 11 December 2014

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice

scientific article published on 16 October 2009

Distinct Redox Signalling following Macrophage Activation Influences Profibrotic Activity

scientific article published on 11 November 2019

Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo.

scientific article published on 5 November 2015

Effect of a broad-specificity chemokine-binding protein on brain leukocyte infiltration and infarct development.

scientific article published on 23 December 2014

Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen.

scientific article published on 24 May 2007

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

scientific article

Endothelial NADPH oxidases: which NOX to target in vascular disease?

scientific article

Estrogen: reducing the pressure by arginine vasopressin

scientific article published on 22 December 2020

Evidence That Ly6C(hi) Monocytes are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization.

scientific article

Evidence of CCR2-independent transmigration of Ly6C(hi) monocytes into the brain after permanent cerebral ischemia in mice.

scientific article

Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke

scientific article published on 14 January 2017

Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice

scientific article published on 16 October 2009

Flow-induced cerebral vasodilatation in vivo involves activation of phosphatidylinositol-3 kinase, NADPH-oxidase, and nitric oxide synthase

scientific article

Gender influences cerebral vascular responses to angiotensin II through Nox2-derived reactive oxygen species

scientific article published on 10 February 2009

Ghrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s).

scientific article

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle.

scientific article published on 09 September 2016

Hyperuricemia is independently associated with hypertension in men under 60 years in a general Chinese population

scientific article published on 14 December 2020

IL-1β and IL-18: inflammatory markers or mediators of hypertension?

scientific article

IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke

scientific article published on 20 September 2018

IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice

scientific article published on 06 May 2019

Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia.

scientific article published on 11 December 2013

Immune mechanisms in vascular disease and stroke

scientific article published on 14 August 2014

Immune mechanisms of hypertension.

scientific article

Immunity and hypertension: New targets to lighten the pressure

scientific article published on 01 June 2019

Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

scientific article published on 25 June 2009

Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia.

scientific article published in February 2012

Increased NADPH oxidase activity, gp91phox expression, and endothelium-dependent vasorelaxation during neointima formation in rabbits

scientific article

Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo

scientific article

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

scientific article published on 23 June 2015

Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation

scientific article published in 2011

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

scientific article published on 05 September 2013

M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.

scientific article published on 12 June 2015

Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide

scientific article

Mild Closed-Head Injury in Conscious Rats Causes Transient Neurobehavioral and Glial Disturbances: A Novel Experimental Model of Concussion

scientific article published on 10 April 2019

Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.

scientific article

NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries

scientific article

NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2.

scientific article published on 21 November 2008

NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival.

scientific article

NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts

scientific article published on 23 March 2012

NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.

scientific article published on 28 August 2008

NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors

scientific article published on 11 January 2006

NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis.

scientific article published on February 2015

NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development

article

NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages

scientific article

Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo.

scientific article

New opportunities for targeting redox dysregulation in cardiovascular disease

scientific article published on 01 March 2020

Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells.

scientific article

Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization

scientific article

Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity.

scientific article published on 28 February 2013

Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology

scientific article published on November 2003

Novel isoforms of NADPH-oxidase in cerebral vascular control.

scientific article

Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models.

scientific article published on January 2010

Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.

scientific article

Nox1 upregulates the function of vascular T-type calcium channels following chronic nitric oxide deficit

scientific article published on 14 June 2014

Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke.

scientific article

Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension

scientific article published on 8 September 2015

Over-expression of DSCR1 protects against post-ischemic neuronal injury

scientific article

Oxidative stress and endothelial dysfunction in cerebrovascular disease

scientific article published on January 2011

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.

scientific article

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage and dysfunction in salt-sensitive hypertension

scientific article published on 01 March 2019

Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells

scientific article published on January 2012

Potential Efficacy of Amnion Epithelial Cells to Treat Post-stroke Inflammation

scientific article published in 2014

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

scientific article published on 28 June 2017

Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization.

scientific article published on 6 March 2018

Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells

scientific article published on 6 December 2007

Reactive oxygen species in the cerebral circulation: are they all bad?

scientific article published on July 2006

Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke

scientific article published in January 2004

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

scientific article published on 10 June 2016

Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits

scientific article published on 21 March 2005

Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.

scientific article published on October 2008

Reduced cerebrovascular remodeling and functional impairment in spontaneously hypertensive rats following combined treatment with suboptimal doses of telmisartan and ramipril: is less really more?

scientific article published on July 2010

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice.

scientific article published on 23 January 2009

Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

scientific article published on 19 August 2019

Reversal of Vascular Macrophage Accumulation and Hypertension by a CCR2 Antagonist in Deoxycorticosterone/Salt-Treated Mice

scientific article published on 01 October 2012

Risk of Major Cardiovascular Events in People with Down Syndrome

scientific article published on 30 September 2015

Role of CCR2 in inflammatory conditions of the central nervous system

scientific article

Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension.

scientific article published on 12 February 2016

Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension

scientific article

Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke.

scientific article

Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice

scientific article published in August 2012

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients

scientific article published on 04 February 2019

Suppression of oxidative stress in the endothelium and vascular wall

scientific article published in March 2004

The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms".

scientific article

The Vascular Consequences of Metabolic Syndrome: Rodent Models, Endothelial Dysfunction, and Current Therapies

scientific article published on 04 March 2020

The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity

scientific article published on September 2010

The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo

scientific article published on 27 March 2007

The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle

scientific article published in February 2005

The opposing roles of NO and oxidative stress in cardiovascular disease.

scientific article published on 14 December 2016

Unexpected anti-hypertrophic responses to low-level stimulation of protease-activated receptors in adult rat cardiomyocytes.

scientific article published on August 2014

Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress

scientific article published on 08 August 2012

Vasoactive actions of nitroxyl (HNO) are preserved in resistance arteries in diabetes

scientific article published on 10 January 2017

Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia

scientific article published on 29 July 2011

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke.

scientific article published on 23 February 2018

Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat.

scientific article

microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke

scientific article published on 11 July 2019