List of works by Irini Sereti

A Paradoxical Treatment for a Paradoxical Condition: Infliximab Use in Three Cases of Mycobacterial IRIS.

scientific article

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Chemokine Receptor 5 (CCR5) Antagonist to Decrease the Occurrence of Immune Reconstitution Inflammatory Syndrome in HIV-Infection: The CADIRIS Study

scientific article

A randomized, double-blinded, placebo-controlled trial of intermittent administration of interleukin-2 and prednisone in subjects infected with human immunodeficiency virus

scientific article published on 31 July 2003

Acute tubular nephropathy in a patient with acute HIV infection: review of the literature

scientific article

Administration of interleukin-7 increases CD4 T cells in idiopathic CD4 lymphocytopenia.

scientific article published on 16 December 2015

Alopecia universalis and Graves’ disease in the setting of immune restoration after highly active antiretroviral therapy

scientific article published on 01 January 2001

BAY 50-4798, a novel, high-affinity receptor-specific recombinant interleukin-2 analog, induces dose-dependent increases in CD25 expression and proliferation among unstimulated, human peripheral blood mononuclear cells in vitro

scientific article published on 01 December 2004

Biomarkers in immune reconstitution inflammatory syndrome: signals from pathogenesis

scientific article

Biomarkers of inflammation and coagulation are associated with mortality and hepatitis flares in persons coinfected with HIV and hepatitis viruses

scientific article published on 18 January 2013

CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients

article

CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients

scientific article published on September 2008

CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors

scientific article

CD4+T Cell Responses to Interleukin‐2 Administration in HIV‐Infected Patients Are Directly Related to the Baseline Level of Immune Activation

article

Can early therapy reduce inflammation?

scientific article

Cardiovascular Biomarker Profile on Antiretroviral Therapy Is Not Influenced by History of an IRIS Event in People With HIV and Suppressed Viremia

scientific article published on 11 January 2020

Cerebrospinal fluid HIV-1 compartmentalization in a patient with AIDS and acute varicella-zoster virus meningomyeloradiculitis.

scientific article published on 31 May 2013

Changing lanes in ICL

scientific article published on 01 May 2010

Clinical Features and Outcomes of Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-associated Inflammation: Prospective Characterization of KSHV Inflammatory Cytokine Syndrome (KICS).

scientific article

Clinically Indicated Corticosteroids Do Not Affect Bone Turnover During Immune Restoration of Severely Lymphopenic HIV-Infected Patients

scientific article published on 21 May 2015

Complement activation by HIV-1-infected target cells enhances IL-2-stimulated but not unstimulated ADCC activity mediated by peripheral blood mononuclear cells

scientific article

Comprehensive analysis of unique cases with extraordinary control over HIV replication

scientific article

Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons

scientific article published on 26 March 2013

Corrigendum to “D-Dimer and CRP levels are elevated prior to antiretroviral treatment in patients who develop IRIS” [Clin. Immunol. 136 (2010) 42–50]

scholarly article published in Clinical Immunology

Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels

scientific article

Cytomegalovirus immune reconstitution inflammatory syndrome manifesting as acute appendicitis in an HIV-infected patient

scientific article

Cytomegalovirus immune reconstitution inflammatory syndrome manifesting as sialadenitis in an HIV-infected patient.

scientific article published in July 2013

Cytomegalovirus retinitis successfully treated with ganciclovir implant in a patient with blood ganciclovir resistance and ocular ganciclovir sensitivity

scientific article published on 10 February 2012

Decreased CD127 expression on T Cells in HIV-1-infected adults receiving antiretroviral therapy with or without intermittent IL-2 therapy

scientific article published in August 2006

Decreased interleukin 7 responsiveness of T lymphocytes in patients with idiopathic CD4 lymphopenia

scientific article published on 26 March 2012

Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance

scientific article

Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration

scientific article published on 30 January 2014

Delayed Sample Processing Leads to Marked Decreases in Measured Plasma IL-7 Levels

scientific article published on 01 August 2006

Detection of EBV genomes in plasmablasts/plasma cells and non-B cells in the blood of most patients with EBV lymphoproliferative disorders by using Immuno-FISH.

scientific article

Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes

scientific article

Disseminated nocardiosis in a patient with X-linked chronic granulomatous disease and human immunodeficiency virus infection

scientific article published on 15 June 2001

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy

scientific article published on 8 December 2017

Effect of intermittent interleukin-2 therapy on CD4+ T-cell counts following antiretroviral cessation in patients with HIV

article

Effect of the CCR5 antagonist maraviroc on the occurrence of immune reconstitution inflammatory syndrome in HIV (CADIRIS): a double-blind, randomised, placebo-controlled trial

article by Juan G Sierra-Madero et al published 21 October 2014 in The lancet. HIV

Effects of delays in peripheral blood processing, including cryopreservation, on detection of CD31 expression on naive CD4 T cells

scientific article published on 30 April 2008

Effects of lymphocyte isolation and timing of processing on detection of CD127 expression on T cells in human immunodeficiency virus-infected patients

scientific article

Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study

scientific article

Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome

scientific article

Elevated interleukin 8 and T-helper 1 and T-helper 17 cytokine levels prior to antiretroviral therapy in participants who developed immune reconstitution inflammatory syndrome during ACTG A5164.

scientific article

Evidence for innate immune system activation in HIV type 1-infected elite controllers.

scientific article

Evidence for translocation of microbial products in patients with idiopathic CD4 lymphocytopenia.

scientific article published on June 2009

Factor Xa Inhibition Reduces Coagulation Activity but Not Inflammation Among People With HIV: A Randomized Clinical Trial

scientific article published on 01 February 2020

Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection

scientific article published in December 2004

Graves' disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4(+) T-cell recovery

scientific article published on January 2014

HIV Infection and the Gut: Scarred for Life?

article

HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy

scientific article

HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases

scientific article published on 15 May 2020

Helper T cell immunity in humans with inherited CD4 deficiency

scientific article published in 2024

Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis

scientific article

High prevalence of gastrointestinal manifestations among Cytomegalovirus end-organ disease in the combination antiretroviral era

scientific article published in 2021

Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death

scientific article

IL-15 acts as a potent inducer of CD4(+)CD25(hi) cells expressing FOXP3.

scientific article published on June 2008

IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation

scientific article

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

scientific article published on 20 April 2009

IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa

scientific article

Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV

scientific article

Idiopathic CD4 Lymphopenia

Idiopathic CD4 lymphocytopenia: a case of missing, wandering or ineffective T cells

scientific article published on 31 August 2012

Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors

scientific article

Immune activation and HIV: an enduring relationship

scientific article published on March 2016

Immune activation is associated with CD8 T cell interleukin-21 production in HIV-1-infected individuals

scientific article

Immune reconstitution disorders in patients with HIV infection: from pathogenesis to prevention and treatment.

scientific article published on September 2014

Immune reconstitution inflammatory syndrome in HIV infection: taking the bad with the good

scientific article published on November 2016

Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none

scientific article

Immune restoration after antiretroviral therapy: the pitfalls of hasty or incomplete repairs.

scientific article

Immunologic Effects of Maraviroc in HIV-Infected Patients with Severe CD4 Lymphopenia Starting Antiretroviral Therapy: A Sub-Study of the CADIRIS Trial

scientific article

Immunologic predictors of coronary artery calcium progression in a contemporary HIV cohort

scientific article

Immunometabolism and HIV-1 pathogenesis: food for thought

scientific article published on 06 August 2020

Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm

scientific article

Immunopathogenesis of human immunodeficiency virus: implications for immune-based therapies.

scientific article

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection

scientific article

In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients

scientific article

Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection

scientific article

Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients

scientific article published on 14 July 2005

Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: a randomized controlled trial

scientific article

Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection

scientific article published on 26 August 2020

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy.

scientific article published on August 2017

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

scientific article

Interleukin 2 Leads to Dose-Dependent Expression of the Alpha Chain of the IL-2 Receptor on CD25-Negative T Lymphocytes in the Absence of Exogenous Antigenic Stimulation

scientific article published on 01 December 2000

Interleukin-2 cycling causes transient increases in high-sensitivity C-reactive protein and D-dimer that are not associated with plasma HIV-RNA levels

scientific article published on September 2009

Interleukin-7 promotes HIV persistence during antiretroviral therapy

scientific article published on 15 April 2013

Interruption of antiretroviral therapy blunts but does not abrogate CD4 T-cell responses to interleukin-2 administration in HIV infected patients

article

Lack of compartmentalization of HIV-1 quasispecies between the gut and peripheral blood compartments

scientific article

Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.

scientific article

Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection

scientific article

Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome

scientific article

Naïve T-cell dynamics in human immunodeficiency virus type 1 infection: effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion

scientific article

Obesity is associated with greater inflammation and monocyte activation among HIV-infected adults receiving antiretroviral therapy

scientific article published on October 2015

Paradoxical tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) in HIV patients with culture confirmed pulmonary tuberculosis in India and the potential role of IL-6 in prediction

scientific article

Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases

scientific article

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

scientific article

Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy

scientific article published on 12 May 2016

Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

scientific article published on February 2015

Plasma levels of soluble CD14 independently predict mortality in HIV infection

scientific article

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study

scientific article

Preliminary evaluation of a highly automated instrument for the selection of CD34+ cells from mobilized peripheral blood stem cell concentrates

scientific article

Prevalence of Strongyloides stercoralis in an urban US AIDS cohort

scientific article published on August 2012

Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection

scientific article

Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies

scientific article published on 7 February 2016

Reply to Tham et al.

scientific article published on 25 May 2016

Response to Bandera et al

scientific article published on 19 March 2015

Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection

scientific article

Role of IL-6 in Mycobacterium avium--associated immune reconstitution inflammatory syndrome

scientific article published on 11 December 2013

Selective expansion of polyfunctional pathogen-specific CD4(+) T cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome

scientific article published on 4 January 2012

Serious Non-AIDS Events: Therapeutic Targets of Immune Activation and Chronic Inflammation in HIV Infection

scientific article published on 25 February 2016

Serious Non-AIDS events: Immunopathogenesis and interventional strategies

scientific article published on 13 December 2013

Severe Paradoxical Reaction During Treatment of Disseminated Tuberculosis in a Patient With Neutralizing Anti-IFNγ Autoantibodies

scientific article published on 8 December 2015

Susceptibility to Cryptococcal Meningoencephalitis Associated With Idiopathic CD4+ Lymphopenia and Secondary Germline or Acquired Defects

scientific article

T-Cell Depletion in the Colonic Mucosa of Patients With Idiopathic CD4+ Lymphopenia

scientific article

Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice.

scientific article

The Complement Pathway Is Activated in People With Human Immunodeficiency Virus and Is Associated With Non-AIDS Comorbidities

publication published on 01 October 2021

The effect of continuous versus pericycle antiretroviral therapy on IL-2 responsiveness

scientific article published on July 2008

The effect of intermittent IL-2 therapy on CD4 T cells in the gut in HIV-1-infected patients

scientific article

The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants.

scientific article

The power of 1 in HIV therapeutics

article

Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection

scientific article

Transmitted HIV Drug Resistance Is High and Longstanding in Metropolitan Washington, DC

scientific article

Transmitted raltegravir resistance in an HIV-1 CRF_AG-infected patient

scientific article

Treatment of progressive multifocal leukoencephalopathy with interleukin 7.

scientific article published on August 2014

Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons

scientific article

Vitamin D, D-dimer, Interferon γ, and sCD14 Levels are Independently Associated with Immune Reconstitution Inflammatory Syndrome: A Prospective, International Study

scientific article published on 14 January 2016

Where have all the T cells gone?

scientific article published in July 2009

d-Dimer and CRP levels are elevated prior to antiretroviral treatment in patients who develop IRIS.

scientific article

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