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List of works by Paul R. Albert

17β-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells

scientific article

5-HT1A receptors, gene repression, and depression: guilt by association

scientific article

5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to the nucleus

scientific article

A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression.

scientific article published on 7 August 2018

A Nurr1 point mutant, implicated in Parkinson's disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription

scientific article

A Putative alpha-helical Gbetagamma-coupling Domain in the Second Intracellular Loop of the 5-HT1A Receptora

scientific article published on 01 December 1998

A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels

scientific article

A functional alternative splicing mutation in human tryptophan hydroxylase-2.

scientific article

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

scientific article

Abrogated Freud-1/Cc2d1a Repression of 5-HT1A Autoreceptors Induces Fluoxetine-Resistant Anxiety/Depression-Like Behavior.

scientific article published on 3 November 2017

Adult neuroplasticity: A new “cure” for major depression?

scientific article published on 01 March 2019

Antisense knockouts: molecular scalpels for the dissection of signal transduction

scientific article published on 01 July 1994

Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential

scientific article published on 08 May 2019

Brain derived neurotrophic factor, cardiopulmonary fitness and cognition in patients with coronary artery disease

scientific article

COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers

scientific article published on 15 July 2015

Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene

scientific article (publication date: February 2004)

Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism.

scientific article published on February 2006

Characterization of rat rostral raphe primary cultures: multiplex quantification of serotonergic markers

scientific article published on 7 April 2007

Cholera toxin-sensitive 3',5'-cyclic adenosine monophosphate and calcium signals of the human dopamine-D1 receptor: selective potentiation by protein kinase A ⬇️

scientific article published on November 1, 1992

Chronic Fluoxetine Induces Activity Changes in Recovery From Poststroke Anxiety, Depression, and Cognitive Impairment

scientific article

Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site

scientific article

Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies

scientific article published on 12 December 2015

Coupling of 5-HT1A autoreceptors to inhibition of mitogen-activated protein kinase activation via G beta gamma subunit signaling.

scientific article published on February 2005

DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA.

scientific article published on 11 July 2013

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

scientific article

Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression

scientific article

Depression, dementia and immune dysregulation

scientific article published on 05 December 2020

Diacylglycerol and ceramide formation induced by dopamine D2S receptors via Gbeta gamma -subunits in Balb/c-3T3 cells

scientific article published on 13 November 2002

Differential desensitization of dopamine D2 receptor isoforms by protein kinase C: The importance of receptor phosphorylation and pseudosubstrate sites

scientific article published on 25 August 2007

Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress

scientific article published on 30 July 2009

Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene

scientific article

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death

scientific journal article

Differential sensitivity of the short and long human dopamine D2 receptor subtypes to protein kinase C

scientific article published on December 1, 1992

Differential signaling of dopamine-D2S and -D2L receptors to inhibit ERK1/2 phosphorylation

scientific article published on September 2007

Distinct Roles for Gαi2, Gαi3, and Gβγ in Modulation of Forskolin- or Gs-mediated cAMP Accumulation and Calcium Mobilization by Dopamine D2S Receptors

scientific article published in Journal of Biological Chemistry

Dopamine-D2-mediated inhibition of TRH-induced PLC activation in pituitary cells-direct or indirect?

scientific article published in March 2002

Dopamine-D2S receptor inhibition of calcium influx, adenylyl cyclase, and mitogen-activated protein kinase in pituitary cells: distinct Galpha and Gbetagamma requirements

scientific article

Drugs for kids: Good or bad? ⬇️

scientific article published on September 1, 2012

Editorial. Thematic section: serotonin and its receptors

scientific article published on November 2014

Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors

scientific article

Effects of nicotine on the amplitude and gating of the auditory P50 and its influence by dopamine D2 receptor gene polymorphism

scientific article published on 2 December 2009

Endogenous serotonin-2A and -2C receptors in Balb/c-3T3 cells revealed in serotonin-free medium: desensitization and down-regulation by serotonin

scientific article

Epigenetics in mental illness: Hope or hype? ⬇️

scientific article published on November 1, 2010

Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders

scientific article

Expression of adenylyl cyclase-4 (AC-4) in Y1 and forskolin-resistant adrenal cells

scientific article published on February 2004

Fluoxetine-induced recovery of serotonin and norepinephrine projections in a mouse model of post-stroke depression

scientific article published on 30 September 2020

Forskolin-resistant Y1 adrenal cell mutants are deficient in adenylyl cyclase type 4.

scientific article published on February 2004

Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene

scientific journal article

G protein preferences for dopamine D2 inhibition of prolactin secretion and DNA synthesis in GH4 pituitary cells

scientific article published on August 2002

G protein specificity: traffic direction required.

scientific article

GAP1(IP4BP)/RASA3 mediates Galphai-induced inhibition of mitogen-activated protein kinase

scientific article

Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder.

scientific article published on 19 June 2008

Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm

scientific article published on 01 May 2019

Growth hormone-induced diacylglycerol and ceramide formation via Galpha i3 and Gbeta gamma in GH4 pituitary cells. Potentiation by dopamine-D2 receptor activation

scientific article published on 9 October 2002

HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: essential role in developmental expression

scientific article

Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression

scientific article

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice

scientific article published on 9 January 2012

Is poststroke depression the same as major depression?

scientific article

Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression.

scientific article published on 12 July 2017

Light up your life: optogenetics for depression?

scientific article published on January 2014

Loss of Adult 5-HT1A Autoreceptors Results in a Paradoxical Anxiogenic Response to Antidepressant Treatment

scientific article published on 14 December 2018

Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes

scientific article published on 10 April 2018

Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression

scientific article

Modifying 5-HT1A Receptor Gene Expression as a New Target for Antidepressant Therapy.

scientific article

Molecular biology of the 5-HT1A receptor: Low-stringency cloning and eukaryotic expression

scientific article published on 01 July 1992

Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling

scientific article

Neurotensin triggers dopamine D2 receptor desensitization through a protein kinase C and beta-arrestin1-dependent mechanism

scientific article

Novel dual repressor elements for neuronal cell-specific transcription of the rat 5-HT1A receptor gene

scientific article published in March 2000

Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity

scientific article published on 30 April 2019

Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke

scientific article published on 2 August 2016

RGS17/RGSZ2 and the RZ/A family of regulators of G-protein signaling.

scientific article published on 7 April 2006

Receptor selectivity of the cloned opossum G protein-coupled receptor kinase 2 (GRK2) in intact opossum kidney cells: role in desensitization of endogenous alpha2C-adrenergic but not serotonin 1B receptors

scientific article published on January 1999

Recruitment by the Repressor Freud-1 of Histone Deacetylase-Brg1 Chromatin Remodeling Complexes to Strengthen HTR1A Gene Repression.

scientific article

Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo.

scientific article

Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

scientific article

Role of protein kinase C in agonist-induced desensitization of 5-HT₁A receptor coupling to calcium channels in F11 cells

scientific article published on 16 March 2013

Roles of G protein and beta-arrestin in dopamine D2 receptor-mediated ERK activation

scientific article published on 20 October 2008

Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine-induced adenylyl cyclase sensitization but not mitogen-activated protein kinase phosphorylation

scientific article

Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression

scientific article

Sex-dependent adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice

scientific article published on 03 August 2016

Stimulation of cAMP synthesis by Gi-coupled receptors upon ablation of distinct Galphai protein expression. Gi subtype specificity of the 5-HT1A receptor

scientific article published on June 1999

Stress-induced alterations in 5-HT1A receptor transcriptional modulators NUDR and Freud-1

scientific article published on 19 June 2014

TATA-driven transcriptional initiation and regulation of the rat serotonin 5-HT1A receptor gene

scientific article published on June 1999

TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.

scientific article

Targeting Homer1a for Rapid Antidepressant Effects

scientific article published on 01 October 2019

The 5-HT1A receptor: Signaling to behavior

scientific article published on 25 October 2018

The 5-HT1A receptor: signaling, desensitization, and gene transcription

scientific article published on January 1996

The Freud-1/CC2D1A family: transcriptional regulators implicated in mental retardation.

scientific article published on October 2007

The Transcription Factor Deaf1 Modulates Engrailed-1 Expression to Regulate Skin Appendage Fate

scientific article published on 28 May 2019

The adaptive brain in mental health: overcoming inherited risk factors.

scientific article published on January 2017

The expression of KLF11 (TIEG2), a monoamine oxidase B transcriptional activator in the prefrontal cortex of human alcohol dependence

scientific article published on 05 August 2013

The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription

scientific article published on March 2016

The mental retardation gene CC2D1A/Freud-1 encodes a long isoform that binds conserved DNA elements to repress gene transcription

scientific article (publication date: August 2007)

The moderating role of the dopamine transporter 1 gene on P50 sensory gating and its modulation by nicotine ⬇️

scientific article published on February 16, 2011

The neurobiology of depression--revisiting the serotonin hypothesis. I. Cellular and molecular mechanisms

scientific article published in September 2012

The neurobiology of depression--revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies

scientific article published on 25 February 2013

The next frontier in the molecular biology of the opioid system. The opioid receptors

scientific article

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1

scientific article

The reduction of R1, a novel repressor protein for monoamine oxidase A, in major depressive disorder

scientific article

Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness ⬇️

scientific article published on May 27, 2011

Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes

scientific article published on 15 November 2000

Transcriptional regulation at a HTR1A polymorphism associated with mental illness.

scientific article published on 29 June 2008

Transcriptional regulation of the 5-HT1A receptor: implications for mental illness

scientific article

What is a functional genetic polymorphism? Defining classes of functionality ⬇️

scientific article published on November 1, 2011

Why is depression more prevalent in women?

scientific article published on July 2015

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