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List of works by Lawrence Fleckenstein

A urine metabolic ratio of dextromethorphan and 3-methoxymorphinan as a probe for CYP3A activity and prediction of cyclosporine clearance in healthy volunteers.

scientific article

AAPS-FIP summary workshop report: Pharmacogenetics in individualized medicine: methods, regulatory, and clinical applications

scientific article published on 25 March 2009

Clinical pharmacokinetics of suramin in patients with onchocerciasis

scientific article published in May 1998

Comparison of the pharmacokinetics of moxidectin and ivermectin after oral administration to beagle dogs

scientific article published in November 2007

Corrigendum to the “Safety, tolerability, efficacy and plasma concentrations of diethylcarbamazine and albendazole co-administration in a field study in an area endemic for lymphatic in India” [Transactions of the Royal Society of Tropical Medici

scholarly article published in Transactions of the Royal Society of Tropical Medicine and Hygiene

Current medical practice and the Food and Drug Administration. Some evidence for the existing gap

scientific article published on 01 September 1974

Development and validation of a high-performance liquid chromatography-mass spectroscopy assay for determination of artesunate and dihydroartemisinin in human plasma

scientific article

Development and validation of a liquid chromatography-mass spectrometry assay for the determination of pyronaridine in human blood for application to clinical pharmacokinetic studies.

scientific article

Development and validation of a liquid chromatography-mass spectrometry assay for the determination of pyronaridine in human urine

scientific article

Drug-Drug Interaction Analysis of Pyronaridine/Artesunate and Ritonavir in Healthy Volunteers ⬇️

scientific article published on March 1, 2012

Effects of body size and gender on the population pharmacokinetics of artesunate and its active metabolite dihydroartemisinin in pediatric malaria patients

scientific article published on 16 September 2013

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

scientific article published in April 2010

Excretion of moxidectin into breast milk and pharmacokinetics in healthy lactating women

scientific article

Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon

scientific article published in September 2008

Gas chromatographic assay of diethylcarbamazine in human plasma for application to clinical pharmacokinetic studies

scientific article published in November 2001

HPLC assay for albendazole and metabolites in human plasma for clinical pharmacokinetic studies

scientific article published in October 2002

Liquid chromatographic assay of ivermectin in human plasma for application to clinical pharmacokinetic studies

scientific article published on 19 October 2005

Liquid chromatographic assay of moxidectin in human plasma for application to pharmacokinetic studies

scientific article published in July 2002

Non-Oral Treatment with Ivermectin for Disseminated Strongyloidiasis ⬇️

scientific article published on October 1, 2010

Oral contraceptive patient information. A questionnaire study of attitudes, knowledge, and preferred information sources

scientific article published in March 1976

Pharmacokinetics and dose proportionality of oral moxidectin in beagle dogs

scientific article published in October 2002

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.

scientific article

Pharmacokinetics of an extended-dose halofantrine regimen in patients with malaria and in healthy volunteers

scientific article published in May 1995

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

scientific article

Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria ⬇️

scientific article

Population pharmacokinetics of telapristone (CDB-4124) and its active monodemethylated metabolite CDB-4453, with a mixture model for total clearance.

scientific article published on 25 October 2011

Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial

scientific article

Pyronaridine-artesunate versus mefloquine plus artesunate for malaria

scientific article published in April 2012

Relative Bioavailability of Liquid and Tablet Formulations of the Antiparasitic Moxidectin

scientific article published in January 2012

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

scientific article published on 13 September 2011

Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials

scientific article

Safety, tolerability, efficacy and plasma concentrations of diethylcarbamazine and albendazole co-administration in a field study in an area endemic for lymphatic filariasis in India

scientific article published in April 2004

Serum ivermectin levels after enteral and subcutaneous administration for Strongyloides hyperinfection: a case report

scientific article published in March 2010

Simultaneous modeling of the pharmacokinetics and methemoglobin pharmacodynamics of an 8-aminoquinoline candidate antimalarial (WR 238605).

scientific article published in December 1991

Specific gas chromatographic analysis of diethylcarbamazine in human plasma using solid-phase extraction ⬇️

scientific article published on December 19, 1997

The antiparasitic moxidectin: safety, tolerability, and pharmacokinetics in humans

scientific article published in October 2003

The effect of a high-fat breakfast on the pharmacokinetics of moxidectin in healthy male subjects: a randomized phase I trial

scientific article published on January 2012

The pharmacokinetics, safety and tolerability of the co-administration of diethylcarbamazine and albendazole

scientific article published in September 2002

UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.

scientific article published on 20 June 2008

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