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List of works by Joseph Casey

A biochemical framework for SLC4A11, the plasma membrane protein defective in corneal dystrophies

scientific article published on 14 February 2011

A novel carbonic anhydrase II binding site regulates NHE1 activity

scientific article published in February 2006

A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters

scientific article

A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers

scientific article (publication date: 21 December 2001)

AE3 anion exchanger isoforms in the vertebrate retina: developmental regulation and differential expression in neurons and glia.

scientific article

An intramolecular transport metabolon: fusion of carbonic anhydrase II to the COOH terminus of the Cl(-)/HCO(3)(-)exchanger, AE1

scientific article published on 04 May 2011

Analysis of the oligomeric state of Band 3, the anion transport protein of the human erythrocyte membrane, by size exclusion high performance liquid chromatography. Oligomeric stability and origin of heterogeneity

scientific article published in August 1991

Anion exchangers in the red cell and beyond.

scientific article

Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools ⬇️

scientific article published on December 1, 2011

Bicarbonate homeostasis in excitable tissues: role of AE3 Cl-/HCO3- exchanger and carbonic anhydrase XIV interaction

scientific article

Bicarbonate transport in health and disease

scientific article published on September 2014

Bicarbonate transport proteins.

scientific article

Bicarbonate transporters in corals point towards a key step in the evolution of cnidarian calcification

scientific article published on 4 June 2015

Biosynthetic and functional defects in newly identified SLC4A11 mutants and absence of COL8A2 mutations in Fuchs endothelial corneal dystrophy

scientific article published on 10 July 2014

Blindness caused by deficiency in AE3 chloride/bicarbonate exchanger

scientific article

Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger

scientific article (publication date: 27 September 2002)

Carbonic anhydrase II binds to and increases the activity of the epithelial sodium-proton exchanger, NHE3

scientific article published on 03 June 2015

Carbonic anhydrase II promotes cardiomyocyte hypertrophy

scientific article published on 23 November 2012

Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophy ⬇️

scientific article published on 23 November 2006

Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1.

scientific article

Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.

scientific article published in April 2004

Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates

scientific article published in February 2005

Cardiac hypertrophy in anion exchanger 1-null mutant mice with severe hemolytic anemia

scientific article published on 20 October 2006

Characterization of an epilepsy-associated variant of the human Cl-/HCO3(-) exchanger AE3.

scientific article

Corneal dystrophy-causing SLC4A11 mutants: suitability for folding-correction therapy

scientific article

Cysteine-directed cross-linking localizes regions of the human erythrocyte anion-exchange protein (AE1) relative to the dimeric interface

scientific article

Cytosolic H+ microdomain developed around AE1 during AE1-mediated Cl-/HCO3- exchange

scientific article published on 7 February 2011

Detergent interaction with band 3, a model polytopic membrane protein

scientific article published on 01 February 1993

Differential roles of tryptophan residues in the functional expression of human anion exchanger 1 (AE1, Band 3, SLC4A1)

scientific article published on 26 September 2014

Distance measurements within a concatamer of the plasma membrane Cl⁻/HCO₃⁻ exchanger, AE1.

scientific article published on November 2010

Enzymatic deglycosylation of human Band 3, the anion transport protein of the erythrocyte membrane. Effect on protein structure and transport properties.

scientific article

Functional assessment of SLC4A11, an integral membrane protein mutated in corneal dystrophies

scientific article published on 24 August 2016

High level expression, partial purification, and functional reconstitution of the human AE1 anion exchanger in Saccharomyces cerevisiae

scientific article published in September 1995

Human Corneal Expression of SLC4A11, a Gene Mutated in Endothelial Corneal Dystrophies

scientific article published on 04 July 2019

Hyperactivity and altered mRNA isoform expression of the Cl(-)/HCO(3)(-) anion-exchanger in the hypertrophied myocardium

scientific article published on 01 July 2001

Identification and characterization of a novel mutation in the carbonic anhydrase IV gene that causes retinitis pigmentosa.

scientific article

Identification of residues lining the translocation pore of human AE1, plasma membrane anion exchange protein

scientific article published on February 1999

Increased water flux induced by an aquaporin-1/carbonic anhydrase II interaction

scientific article

Influence of Na+-independent Cl--HCO3- exchange on the slow force response to myocardial stretch

scientific article published on 23 October 2003

Interaction of integrin-linked kinase with the kidney chloride/bicarbonate exchanger, kAE1

scientific article

Involvement of AE3 isoform of Na(+)-independent Cl(-)/HCO(3)(-) exchanger in myocardial pH(i) recovery from intracellular alkalization

scientific article published on 3 February 2006

JPEN Journal Club 35. Selective Data Presentation

scientific article published on 25 May 2018

Measurement of Intracellular pH.

scientific article published on January 2010

Measurement of intracellular pH

scientific article published on 01 January 2003

Meeting report: The 57th Annual Meeting of the CSMB, Membrane Proteins in Health and Disease

scientific article published on 30 October 2014

Meeting report: membrane proteins in health and disease

scientific article published in January 2002

Molecular characterization of the band 3 protein from Southeast Asian ovalocytes

scientific article

Molecular characterization of the erythrocyte chloride-bicarbonate exchanger

scientific article published on 01 January 1993

Molecular mechanism for the red blood cell senescence clock

scientific article

Molecular phenotype of SLC4A11 missense mutants: Setting the stage for personalized medicine in corneal dystrophies

scientific article

Mutations in sodium-borate cotransporter SLC4A11 cause recessive congenital hereditary endothelial dystrophy (CHED2).

scientific article

Oligomerization of SLC4A11 protein and the severity of FECD and CHED2 corneal dystrophies caused by SLC4A11 mutations

scientific article

Plasma membrane Cl⁻/HCO₃⁻ exchangers: structure, mechanism and physiology.

scientific article published on September 2008

Purification and characterization of band 3 protein

scientific article published on 01 January 1989

Purification of functional human Cl(-)/HCO(3)(-) exchanger, AE1, over-expressed in Saccharomyces cerevisiae

scientific article published on 6 July 2010

Quantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heart

scientific article

Report on the 53rd Annual Meeting of the Canadian Society of Biochemistry, Molecular and Cellular Biology: "Membrane Proteins in Health and Disease".

scientific article

Report on the Bicarbonate Transport Satellite Meeting at the 53rd Annual Meeting of the Canadian Society of Biochemistry, Molecular and Cellular Biology

scientific article published in April 2011

Resistance to cardiomyocyte hypertrophy in ae3-/- mice, deficient in the AE3 Cl-/HCO3- exchanger

scientific article

SLC4A11 mutations in Fuchs endothelial corneal dystrophy

scientific article published on 16 November 2007

Sensors and regulators of intracellular pH.

scientific article published on 09 December 2009

Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart

scientific article

Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain

scientific article

Structure and function of the band 3 Cl-/HCO3- transporter

scientific article published on 01 January 1989

The cytoplasmic domain is essential for transport function of the integral membrane transport protein SLC4A11.

scientific article

The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV

scientific article (publication date: 12 July 2002)

The major kidney AE1 isoform does not bind ankyrin (Ank1) in vitro. An essential role for the 79 NH2-terminal amino acid residues of band 3.

scientific article published on December 1994

The role of cysteine residues in the erythrocyte plasma membrane anion exchange protein, AE1.

scientific article published on April 1995

The substrate anion selectivity filter in the human erythrocyte Cl-/HCO3- exchange protein, AE1.

scientific article published on 24 March 2004

Three-dimensional model for the human Cl-/HCO3- exchanger, AE1, by homology to the E. coli ClC protein

scientific article published on 11 April 2013

Topology of the membrane domain of human erythrocyte anion exchange protein, AE1

scientific article published on 01 March 1999

Topology of the region surrounding Glu681 of human AE1 protein, the erythrocyte anion exchanger

scientific article published on 01 August 1998

Topology of transmembrane proteins by scanning cysteine accessibility mutagenesis methodology.

scientific article

Transmembrane helix-helix interactions and accessibility of H2DIDS on labelled band 3, the erythrocyte anion exchange protein

scientific article published on 01 April 1995

Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases.

scientific article published on 27 June 2013

Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH.

scientific article

Transport activity of chimaeric AE2-AE3 chloride/bicarbonate anion exchange proteins

scientific article published on May 2003

Trapping of inhibitor-induced conformational changes in the erythrocyte membrane anion exchanger AE1

scientific article published on 01 November 1999

Why bicarbonate?

scientific article published on December 2006

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