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List of works by Andrew C Perkins

A case-based discussion of clinical problems in the management of patients treated with ruxolitinib for myelofibrosis

scientific article published in March 2017

A global role for EKLF in definitive and primitive erythropoiesis

scientific article

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

scientific article published on 27 May 2010

A global role for zebrafish klf4 in embryonic erythropoiesis

scientific article published on 23 June 2007

A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing

scientific article

A mechanism for Ikaros regulation of human globin gene switching.

scientific article published on 3 March 2008

A recessive screen for genes regulating hematopoietic stem cells.

scientific article published on 7 July 2010

Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors

scientific article published on 21 May 2019

C/EBPdelta and C/EBPgamma bind the CCAAT-box in the human beta-globin promoter and modulate the activity of the CACC-box binding protein, EKLF

scientific article

Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to an uncommon homozygous MPL p.Y591D mutation

scientific article published on 04 June 2020

Complex architecture and regulated expression of the Sox2ot locus during vertebrate development

scientific article

Conditional immortalization of mouse myelomonocytic, megakaryocytic and mast cell progenitors by the Hox-2.4 homeobox gene.

scientific article

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

scientific article published on 24 May 2019

Diagnosis in subdural myeloid sarcoma

scientific article

Direct targets of pSTAT5 signalling in erythropoiesis.

scientific article published on 21 July 2017

Distinct domains of erythroid Krüppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter

scientific article

Dynamic transcription programs during ES cell differentiation towards mesoderm in serum versus serum-freeBMP4 culture

scientific article

EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.

scientific article published on 20 May 2009

EPO does not promote interaction between the erythropoietin and beta-common receptors

scientific article published in Scientific Reports

Erythroid Krüppel-like factor directly activates the basic Krüppel-like factor gene in erythroid cells.

scientific article published on 5 February 2007

Erythroid Krüppel-like factor is essential for beta-globin gene expression even in absence of gene competition, but is not sufficient to induce the switch from gamma-globin to beta-globin gene expression.

scientific article published in April 1998

Evolution of gene function and regulatory control after whole-genome duplication: comparative analyses in vertebrates.

scientific article published on 13 May 2009

Fetal expression of a human Agamma globin transgene rescues globin chain imbalance but not hemolysis in EKLF null mouse embryos

scientific article published on 01 March 2000

Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4) - a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity.

scientific article

Fulminant postsplenectomy sepsis

scientific article published on 01 January 1988

Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing

scientific article

Genetic Variants Within the Erythroid Transcription Factor, KLF1, and Reduction of the Expression of Lutheran and Other Blood Group Antigens: Review of the In(Lu) Phenotype

scientific article published on 07 February 2019

Genomic organisation and regulation of murine alpha haemoglobin stabilising protein by erythroid Kruppel-like factor

scientific article published on 27 October 2006

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

scientific article published on 01 February 2019

Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

scientific article published on 15 June 2020

Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor

scientific article

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

scientific article published on 28 June 2016

High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci.

scientific article published on 27 July 2017

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain

scientific article

Human KLF17 is a new member of the Sp/KLF family of transcription factors

scientific article

IMMUNE HEMOLYSIS AFTER AN ABO MISMATCHED RENAL TRANSPLANT

scientific article published on 01 August 1989

Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegation

scientific article published on 31 October 2014

Impact of the c-MybE308G mutation on mouse myelopoiesis and dendritic cell development

scientific article

In vitro differentiation of murine embryonic stem cells toward a renal lineage

scientific article published on 5 February 2007

Indian hedgehog supports definitive erythropoiesis

scientific article

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.

scientific article published on 4 March 2014

Investigation of the variable In(Lu) phenotype caused by KLF1 variants

scientific article published on 17 September 2018

Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells

scientific article

JAK1 somatic mutation in a myeloproliferative neoplasm

scientific article published on 26 May 2017

KLF1 directly coordinates almost all aspects of terminal erythroid differentiation.

scientific article

KLF1-null neonates display hydrops fetalis and a deranged erythroid transcriptome.

scientific article

Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular development

scientific article published on 9 March 2006

Krüppel-like factors compete for promoters and enhancers to fine-tune transcription

scientific article

Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

scientific article

Late Relapses in Hodgkin's Disease: Are They a Distinct Entity?

scientific article

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

scientific article

Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis

scientific article

Macrophages and regulation of erythropoiesis

scientific article

Megakaryocyte-erythroid lineage promiscuity in EKLF null mouse blood

scientific article published on 22 October 2009

Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation

scientific article published on 12 November 2007

Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis

scientific article published in Scientific Reports

Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.

scientific article

Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development

scientific article

Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

scientific article

Prediction of novel long non-coding RNAs based on RNA-Seq data of mouse Klf1 knockout study

scientific article

Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability

scientific article

Rapid Molecular Profiling of Myeloproliferative Neoplasms Using Targeted Exon Resequencing of 86 Genes Involved in JAK-STAT Signaling and Epigenetic Regulation.

scientific article

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

scientific article published on 26 June 2018

Stem cell transcriptome profiling via massive-scale mRNA sequencing

scientific article

Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis

scientific article

The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo

scientific article

The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation

scientific article

The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development.

scientific article

Three fingers on the switch: Krüppel-like factor 1 regulation of γ-globin to β-globin gene switching

scientific article published on May 2013

Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor

scientific article published on August 1996

Variable serologic and other phenotypes due to KLF1 mutations

scientific article published on 01 May 2018

Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor

scientific article published in July 2003

Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching

scientific article published in December 2005

neptune, a Krüppel-like transcription factor that participates in primitive erythropoiesis in Xenopus

scientific article published in September 2001

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