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List of works by Manuela Klingler-Hoffmann

2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer

scientific article published in December 2012

Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.

scientific article

Characterisation of a compound in-cis GATA2 germline mutation in a pedigree presenting with myelodysplastic syndrome/acute myeloid leukemia with concurrent thrombocytopenia

scientific article published on 13 February 2015

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

scientific article published on 15 January 2013

Cover Image, Volume 37, Issue 9

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes.

scientific article published on 23 June 2017

Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.

scientific article published on 26 September 2011

Downregulation of protein phosphatase 2A activity in HeLa cells at the G2-mitosis transition and unscheduled reactivation induced by 12-O-tetradecanoyl phorbol-13-acetate (TPA).

scientific article published in August 2005

EZYprep LC-coupled MALDI-TOF/TOF MS: an improved matrix spray application for phosphopeptide characterisation

scientific article

Ectrodactyly and Lethal Pulmonary Acinar Dysplasia Associated with Homozygous FGFR2 Mutations Identified by Exome Sequencing.

scientific article published on 21 June 2016

Egg White as a Quality Control in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI)

scientific article published on 13 November 2019

Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer

scientific article published in May 2014

Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells

scientific article published in June 2003

Lymph node metastasis of primary endometrial cancers: Associated proteins revealed by MALDI imaging.

scientific article

MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia.

scientific article

Mass Spectrometry Analyses of Multicellular Tumour Spheroids.

scientific article published on 11 December 2017

Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for Monitoring of Drug Response in Primary Cancer Spheroids

scientific article published on 15 October 2019

Novel IEF Peptide Fractionation Method Reveals a Detailed Profile of N-Terminal Acetylation in Chemotherapy-Responsive and -Resistant Ovarian Cancer Cells.

scientific article published on 29 August 2016

PI3Kδ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation

scientific article published on 10 March 2011

Proteomics of endometrial cancer diagnosis, treatment, and prognosis.

scientific article

Radiative-SPR platform for the detection of apolipoprotein E for use in medical diagnostics

Radiative-surface plasmon resonance for the detection of apolipoprotein E in medical diagnostics applications.

scientific article

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

scientific article

The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers

scientific article published on 22 October 2019

The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis

scientific article published on June 2004

The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies

scientific article published on 24 January 2017

The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor.

scientific article

Translating N-Glycan Analytical Applications into Clinical Strategies for Ovarian Cancer

scientific article published on 09 November 2018

Tyrosine phosphorylation enrichment and subsequent analysis by MALDI-TOF/TOF MS/MS and LC-ESI-IT-MS/MS.

scientific article

p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.

scientific article