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List of works by Jürgen Burhenne

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CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole

scientific article
Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir

scientific article published on 03 July 2006
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers

scientific article published on July 2004
Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

scientific article
Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients

scientific article
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling

scientific article published on 30 October 2010
Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients

scientific article
Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics

scientific article published in July 2005
Detection of RNA modifications.

scientific article
High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

article
Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine

scientific article published in 2006
In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins

scientific article published on November 2005
Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction

scientific article published on July 2003
Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

article
High absolute bioavailability of methylene blue given as an aqueous oral formulation

scientific article published on 23 September 2008
Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]

scientific article
A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions.

scientific article published on 8 February 2013
Voriconazole concentration in human aqueous humor and plasma during topical or combined topical and systemic administration for fungal keratitis

scientific article published on 23 October 2006
Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using A limited sampling strategy

scientific article published on 21 September 2011
Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania

scientific article
Modulators of very low voriconazole concentrations in routine therapeutic drug monitoring

scientific article
Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy

scientific article published on 18 September 2006
Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics

scientific article published on October 2004
Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

scientific article published on 16 August 2011
Safety of the combination of chloroquine and methylene blue in healthy adult men with G6PD deficiency from rural Burkina Faso

scientific article published on January 2005
Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

scientific article
Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration

scientific article
Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans

scientific article
Aprepitant, granisetron, and dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose melphalan in autologous transplantation for multiple myeloma: results of a randomized, placebo-controlled phase III trial

scientific article published on 15 September 2014
Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria

scientific article published on 13 October 2004
Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40.

scientific article published in May 2003
Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

scientific article published on June 2002
Development of capillary electrophoresis methods for the analysis of fluoroquinolones and application to the study of the influence of humic substances on their photodegradation in aqueous phase

article
CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir

scientific article
A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA.

scientific article
Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement

scientific article published in November 2001
Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent

scientific article published in July 2009
Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients

scientific article published on 23 October 2012
Effect of simultaneous induction and inhibition of CYP3A by St John's Wort and ritonavir on CYP3A activity

scientific article published on 18 November 2009
Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry.

scientific article published on 15 January 2012
Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype.

scientific article published in September 2006
Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters

scientific article
Voriconazole brain tissue levels in rhinocerebral aspergillosis in a successfully treated young woman

scientific article published in September 2006
Efficacy of methylene blue monotherapy in semi-immune adults with uncomplicated falciparum malaria: a controlled trial in Burkina Faso

scientific article published on 29 March 2010
No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment

scientific article
Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure

scientific article published on 7 January 2011
Induction of voriconazole metabolism by rifampin in a patient with acute myeloid leukemia: importance of interdisciplinary communication to prevent treatment errors with complex medications.

scientific article published on 2 July 2007
Oral contraception does not alter single dose saquinavir pharmacokinetics in women

scientific article published in March 2004
CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores

scientific article published on January 2014
Steady-state pharmacokinetics and metabolism of voriconazole in patients.

scientific article published on 13 June 2013

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