List of works - David J Hodson

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets

scientific article published on 01 May 2020

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus.

scientific article

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.

scientific article published on 11 March 2015

A tridimensional view of pituitary development and function

scientific article published on 20 March 2012

ADCY5 couples glucose to insulin secretion in human islets

scientific article

Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish.

scientific article published on 6 April 2018

Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.

scientific article published on 5 April 2016

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

scientific article published on 09 October 2020

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

scientific article published on 20 July 2016

Beta cell connectivity in pancreatic islets: a type 2 diabetes target?

scientific article

Biologically targeted probes for Zn(2+): a diversity oriented modular "click-SNAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the E

scientific article

Cells co-expressing luteinising hormone and thyroid-stimulating hormone are present in the ovine pituitary pars distalis but not the pars tuberalis: implications for the control of endogenous circannual rhythms of prolactin

scientific article

Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function

scientific article

Characterization of the effects of prolactin in gonadotroph target cells

scientific article published on 18 August 2010

Comment on Satin et al. "Take Me To Your Leader": An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets. Diabetes 2020;69:830-836

scientific article published on 01 September 2020

Coordination of calcium signals by pituitary endocrine cells in situ

scientific article published on 14 December 2011

Endocrine cells and blood vessels work in tandem to generate hormone pulses

scientific article published on 25 August 2011

Existence of long-lasting experience-dependent plasticity in endocrine cell networks.

scientific article

Expanded LUXendin Color Palette for GLP1R Detection and Visualization In Vitro and In Vivo

scientific article published on 04 April 2022

Functional importance of blood flow dynamics and partial oxygen pressure in the anterior pituitary

scientific article published on December 2010

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

scientific article published on 4 December 2017

Gonadotropin-releasing hormone stimulates prolactin release from lactotrophs in photoperiodic species through a gonadotropin-independent mechanism

scientific article

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells

scientific article

Incretin-modulated beta cell energetics in intact islets of Langerhans

scientific article

Influence of estrogens on GH-cell network dynamics in females: a live in situ imaging approach

scientific article

Interrogating surface <i>versus</i> intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

scientific article published on 07 July 2020

Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?

scientific article published on 14 September 2015

Investigating and modelling pituitary endocrine network function

scientific article published on December 2010

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

scientific article published on 31 January 2015

Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells

scientific article published on 09 November 2020

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells

scientific article

Lipotoxicity disrupts incretin-regulated human β cell connectivity

scientific article

Local and regional control of calcium dynamics in the pancreatic islet

scientific article published on 3 May 2017

Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects

scientific article

Maternal hypothyroidism in mice influences glucose metabolism in adult offspring

scientific article published on 30 May 2020

Metabolism Regulates Exposure of Pancreatic Islets to Circulating Molecules In Vivo

scientific article published on 18 November 2015

Minireview: intraislet regulation of insulin secretion in humans

scientific article

Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

scientific article

Multiple-scale neuroendocrine signals connect brain and pituitary hormone rhythms

scientific article published on 13 February 2017

Navigating pituitary structure and function - defining a roadmap for hormone secretion

scientific article

New Understanding of β-Cell Heterogeneity and In Situ Islet Function.

scientific article published in April 2018

Optical Control of Insulin Secretion Using an Incretin Switch.

scientific article published on 2 November 2015

Optical control of GPR40 signalling in pancreatic β-cells.

scientific article published on 30 August 2017

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

scientific article

Optical control of insulin release using a photoswitchable sulfonylurea

scientific article

Optical tools for understanding the complexity of β-cell signalling and insulin release

article

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion.

scientific article

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

scientific article published on 30 April 2021

Photoperiodic modulation of the suppressive actions of prolactin and dopamine on the pituitary gonadotropin responses to gonadotropin-releasing hormone in sheep

scientific article

Photoswitchable diacylglycerols enable optical control of protein kinase C.

scientific article published on 25 July 2016

Pituitary endocrine cell networks - 10 years and beyond

scientific article published on 12 April 2012

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood

scientific article

Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release.

scientific article

Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice

scientific article

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor.

scientific article

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice

scientific article published in 2021

RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

scientific article published on 6 June 2017

Remote control of glucose homeostasis in vivo using photopharmacology

scientific article

Rfx6 maintains the functional identity of adult pancreatic β cells.

scientific article

Role of prolactin in the gonadotroph responsiveness to gonadotrophin-releasing hormone during the equine annual reproductive cycle

scientific article

Roles of connexins and pannexins in (neuro)endocrine physiology

scientific article published on 18 June 2015

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

scientific article published on 29 October 2014

Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons.

scientific article published on 13 April 2016

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

scientific article published on 24 January 2020

The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists

scientific article published on 17 March 2020

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion

scientific article

The blood-brain barrier as a regulator of the gut-brain axis

scientific article published on 07 April 2014

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice

scientific article

List of works by David J Hodson

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus.

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.

A tridimensional view of pituitary development and function

ADCY5 couples glucose to insulin secretion in human islets

Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish.

Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

Beta cell connectivity in pancreatic islets: a type 2 diabetes target?

Biologically targeted probes for Zn(2+): a diversity oriented modular "click-SNAr-click" approach†Electronic supplementary information (ESI) available: Full experimental details including characterisation of all novel compounds can be found in the E

Cells co-expressing luteinising hormone and thyroid-stimulating hormone are present in the ovine pituitary pars distalis but not the pars tuberalis: implications for the control of endogenous circannual rhythms of prolactin

Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function

Characterization of the effects of prolactin in gonadotroph target cells

Comment on Satin et al. "Take Me To Your Leader": An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets. Diabetes 2020;69:830-836

Coordination of calcium signals by pituitary endocrine cells in situ

Endocrine cells and blood vessels work in tandem to generate hormone pulses

Existence of long-lasting experience-dependent plasticity in endocrine cell networks.

Expanded LUXendin Color Palette for GLP1R Detection and Visualization In Vitro and In Vivo

Functional importance of blood flow dynamics and partial oxygen pressure in the anterior pituitary

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Gonadotropin-releasing hormone stimulates prolactin release from lactotrophs in photoperiodic species through a gonadotropin-independent mechanism

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells

Incretin-modulated beta cell energetics in intact islets of Langerhans

Influence of estrogens on GH-cell network dynamics in females: a live in situ imaging approach

Interrogating surface <i>versus</i> intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?

Investigating and modelling pituitary endocrine network function

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells

Lipotoxicity disrupts incretin-regulated human β cell connectivity

Local and regional control of calcium dynamics in the pancreatic islet

Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects

Maternal hypothyroidism in mice influences glucose metabolism in adult offspring

Metabolism Regulates Exposure of Pancreatic Islets to Circulating Molecules In Vivo

Minireview: intraislet regulation of insulin secretion in humans

Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

Multiple-scale neuroendocrine signals connect brain and pituitary hormone rhythms

Navigating pituitary structure and function - defining a roadmap for hormone secretion

New Understanding of β-Cell Heterogeneity and In Situ Islet Function.

Optical Control of Insulin Secretion Using an Incretin Switch.

Optical control of GPR40 signalling in pancreatic β-cells.

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Optical control of insulin release using a photoswitchable sulfonylurea

Optical tools for understanding the complexity of β-cell signalling and insulin release

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion.

Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

Photoperiodic modulation of the suppressive actions of prolactin and dopamine on the pituitary gonadotropin responses to gonadotropin-releasing hormone in sheep

Photoswitchable diacylglycerols enable optical control of protein kinase C.

Pituitary endocrine cell networks - 10 years and beyond

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood

Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release.

Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor.

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice

RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Remote control of glucose homeostasis in vivo using photopharmacology

Rfx6 maintains the functional identity of adult pancreatic β cells.

Role of prolactin in the gonadotroph responsiveness to gonadotrophin-releasing hormone during the equine annual reproductive cycle

Roles of connexins and pannexins in (neuro)endocrine physiology

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons.

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists

The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion

The blood-brain barrier as a regulator of the gut-brain axis

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice