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List of works by Thomas L. Richie

A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

scientific article

A consultation on the optimization of controlled human malaria infection by mosquito bite for evaluation of candidate malaria vaccines

scientific article published on 31 May 2012

A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1

scientific article published on 01 May 2020

A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates

scientific article

A systematic review of safety data reporting in clinical trials of vaccines against malaria, tuberculosis, and human immunodeficiency virus

scientific article

A waterborne outbreak of hepatitis E virus transmission in southwestern Vietnam.

scientific article published on June 1996

Acquisition of invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein 1 in a transmigrant population requires multiple infections

scientific article

Adenovectors induce functional antibodies capable of potent inhibition of blood stage malaria parasite growth

scientific article

Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults

scientific article (publication date: 2011)

Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component

scientific article (publication date: 2011)

Advances in immunology and vaccine discovery report of the United States-European Commission workshop

scientific article published on 6 August 2007

Age-dependent impairment of IgG responses to glycosylphosphatidylinositol with equal exposure to Plasmodium falciparum among Javanese migrants to Papua, Indonesia.

scientific article

Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission

scientific article

Associations between responses to the rhoptry-associated membrane antigen of Plasmodium falciparum and immunity to malaria infection

scientific article

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

scientific article published on 21 February 2017

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

scientific article published in June 2019

Boosting of DNA vaccine-elicited gamma interferon responses in humans by exposure to malaria parasites

scientific article

Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria

scientific article

Characterization of immune reactivity profiles using microarray technology may expedite identification of candidate antigens for next generation malaria vaccines

scientific article published in July 2007

Chloroquine-resistant Plasmodium vivax in transmigration settlements of West Kalimantan, Indonesia.

scientific article

Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA

scientific article published on November 2012

Comparative performance of the ParaSight F test for detection of Plasmodium falciparum in malaria-immune and nonimmune populations in Irian Jaya, Indonesia ⬇️

scientific article published on January 1, 1997

Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.

scientific article

Correction: Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies and Induces Protective Immune Responses

scientific article (publication date: 4 May 2012)

Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article published in June 2016

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

scientific article

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

scientific article

Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

scientific article (publication date: 2015)

Early transcriptional responses of HepG2-A16 liver cells to infection by Plasmodium falciparum sporozoites

scientific article

Editorial: Breaking the cycle: attacking the malaria parasite in the liver

scientific article published on 7 August 2015

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.

scientific article published in November 2004

Empowering malaria vaccination by drug administration

scientific article published on 29 April 2010

Etiology of acute, non-malaria, febrile illnesses in Jayapura, northeastern Papua, Indonesia

scientific article

Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vec

scientific article published on 29 October 2013

Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection

scientific article published on 19 March 2021

Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells

scientific article

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers

scientific article published on 8 September 2013

Functional immunoassays using an in-vitro malaria liver-stage infection model: where do we go from here?

scientific article published on 09 September 2009

Genetically attenuated parasite vaccines induce contact-dependent CD8+ T cell killing of Plasmodium yoelii liver stage-infected hepatocytes

scientific article published on 7 October 2009

HLA class II (DR0401) molecules induce Foxp3+ regulatory T cell suppression of B cells in Plasmodium yoelii strain 17XNL malaria

scientific article published on 28 October 2013

Haemoglobin dynamics in Papuan and non-Papuan adults in northeast Papua, Indonesia, with acute, uncomplicated vivax or falciparum malaria

scientific article

Human adenovirus 5-vectoredPlasmodium falciparumNMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection ⬇️

scientific article published on 04 June 2013

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

scientific article

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

scientific article

Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)

scientific article published in 2013

Identification of two new protective pre-erythrocytic malaria vaccine antigen candidates

scientific article

Immune Signature Against Plasmodium falciparum Antigens Predicts Clinical Immunity in Distinct Malaria Endemic Communities

scientific article published on 28 October 2019

Immune evasion by malaria parasites: a challenge for vaccine development

scientific article published on June 2009

Immune responses and protection of Aotus monkeys immunized with irradiated Plasmodium vivax sporozoites

scientific article

Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein

scientific article published in May 2004

Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.

scientific article

Inhibitory antibodies specific for the 19-kilodalton fragment of merozoite surface protein 1 do not correlate with delayed appearance of infection with Plasmodium falciparum in semi-immune individuals in Vietnam

scientific article published on 20 July 2009

Interactions between malaria parasites infecting the same vertebrate host

scientific article

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8 + T Cell Immunity ⬇️

scientific article published on September 8, 2011

Lymphocyte Response to Tetanus Toxoid among Indonesian Men Immunized with Tetanus‐Diphtheria during Extended Chloroquine or Primaquine Prophylaxis ⬇️

scientific article published on December 1, 1997

Malaria in a cohort of Javanese migrants to Indonesian Papua.

scientific article

Malaria vaccines for travelers.

scientific article published in August 2004

Malaria vaccines: are we getting closer?

scientific article published on February 2007

Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults

scientific article

Mefloquine is highly efficacious against chloroquine-resistant Plasmodium vivax malaria and Plasmodium falciparum malaria in Papua, Indonesia

scientific article published on 13 March 2006

Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses

scientific article

Molecular vaccines for malaria

scientific article published on 29 January 2010

Natural regulation of rhesus monkey populations in Kathmandu, Nepal. Rhesus monkey groups near Kathmandu, Nepal, show demographic patterns of intrinsic population stability

scientific article published in January 1981

Naturally acquired antibody responses to the components of the Plasmodium falciparum merozoite surface protein 1 complex

scientific article published in August 2003

Onset of clinical immunity to Plasmodium falciparum among Javanese migrants to Indonesian Papua ⬇️

scientific article published on September 1, 2003

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection

scientific article published on 28 May 2021

Plasmodium falciparum. Mechanisms of innate and acquired protection against Plasmodium falciparum in Javanese transmigrant adults and children newly resident in malaria-endemic Northwest Papua.

scientific article

Primaquine for prophylaxis against malaria among nonimmune transmigrants in Irian Jaya, Indonesia.

scientific article published on June 1995

Primary infection by Plasmodium falciparum or P. vivax in a cohort of Javanese migrants to Indonesian Papua.

scientific article

Progress and challenges for malaria vaccines

scientific article

Progress with PfSPZ Vaccine, a radiation attenuated Plasmodium falciparum sporozoite vaccine

scientific article published on 22 September 2014

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article (publication date: 9 May 2016)

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

scientific article

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

scientific article (publication date: 15 April 2002)

Protection of rhesus monkeys by a DNA prime/poxvirus boost malaria vaccine depends on optimal DNA priming and inclusion of blood stage antigens

scientific article

Protective immunity to pre-erythrocytic stage malaria

scientific article published on 23 March 2011

Purnomo Projodipuro (April 11, 1934–May 10, 2013) ⬇️

scientific article published on August 1, 2013

RTS,S/AS01 malaria vaccine in African children

scientific article published in February 2012

Randomised placebo-controlled trial of primaquine for prophylaxis of falciparum and vivax malaria.

scientific article

Report of a consultation on the optimization of clinical challenge trials for evaluation of candidate blood stage malaria vaccines, 18-19 March 2009, Bethesda, MD, USA.

scientific article published on 3 August 2009

Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

scientific article published on 29 May 2007

Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A.

scientific article published in April 2004

Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes

scientific article published in September 2002

Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes

scientific article

Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies

scientific article published on 10 August 2009

Sterile protective immunity to malaria is associated with a panel of novel P. falciparum antigens

scientific article

Surface-associated antigens of Brugia malayi L2 and L3 parasites during vector-stage development

scientific article published in May 1992

The RTS,S malaria vaccine

scientific article

The march toward malaria vaccines

scientific article published on 28 August 2015

The whole parasite, pre-erythrocytic stage approach to malaria vaccine development: a review

scientific article published on October 2013

Tolerability of azithromycin as malaria prophylaxis in adults in northeast papua, indonesia

scientific article

Towards an optimized inhibition of liver stage development assay (ILSDA) for Plasmodium falciparum

scientific article

Update on the clinical development of candidate malaria vaccines.

scientific article published in August 2004

Use of adenovirus serotype 5 vaccine vectors in seropositive, uncircumcised men: safety lessons from the step trial

scientific article published on 29 November 2012

Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies

scientific article

Utilization of genomic sequence information to develop malaria vaccines ⬇️

scientific article published on November 1, 2003

Vaccines against asexual stage malaria parasites.

scientific article

Vaxfectin enhances both antibody and in vitro T cell responses to each component of a 5-gene Plasmodium falciparum plasmid DNA vaccine mixture administered at low doses

scientific article published on 30 October 2009

Vaxfectin enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccines

scientific article published on 2 November 2005

Viral vectors in malaria vaccine development

scientific article published on September 2009

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