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List of works by Winship Herr

A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer

scientific article published on 01 December 1987

A fragment of 23S RNA containing a nucleotide sequence complementary to a region of 5S RNA

scientific article published on 01 May 1975

A regulated two-step mechanism of TBP binding to DNA: a solvent-exposed surface of TBP inhibits TATA box recognition

scientific article published on 01 March 2002

A shared surface of TBP directs RNA polymerase II and III transcription via association with different TFIIB family members

scientific article published on January 2003

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain

scientific article

A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function.

scientific article published on March 1997

A switch in mitotic histone H4 lysine 20 methylation status is linked to M phase defects upon loss of HCF-1.

scientific article published on June 2004

Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements

scientific article published in December 1988

Basal promoter elements as a selective determinant of transcriptional activator function

scientific article published on April 1995

Compensatory embryonic response to allele-specific inactivation of the murine X-linked gene Hcfc1.

scientific article published on 24 February 2016

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

scientific article

Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16

scientific article

Cycles of gene expression and genome response during mammalian tissue regeneration

article

DNA recognition by the herpes simplex virus transactivator VP16: a novel DNA-binding structure.

scientific article published in July 2001

Developmental and cell-cycle regulation of Caenorhabditis elegans HCF phosphorylation

scientific article published on May 2001

Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA.

scientific article published on December 1985

Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment

scientific article published on January 1993

Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

scientific article (publication date: 9 February 1990)

Distinct OGT-Binding Sites Promote HCF-1 Cleavage

scientific article

Drosophila melanogaster dHCF interacts with both PcG and TrxG epigenetic regulators

scientific article

Duplications of a mutated simian virus 40 enhancer restore its activity

scientific article

E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.

scientific article published in July 2007

E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases

scientific article

Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification

scientific article

Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells

scientific article (publication date: 2007)

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations ⬇️

scientific article (publication date: August 1992)

Gene activation. An agent of suppression

scientific article

Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles

scientific article (publication date: 2012)

Germ-line MuLV reintegrations in AKR/J mice

scientific article published on 01 April 1982

HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

scientific article

HCF-1 amino- and carboxy-terminal subunit association through two separate sets of interaction modules: involvement of fibronectin type 3 repeats

scientific article

HCF-1 self-association via an interdigitated Fn3 structure facilitates transcriptional regulatory complex formation

scientific article

HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy.

scientific article published on 28 March 2013

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

scientific article

Inactivation of the retinoblastoma protein family can bypass the HCF-1 defect in tsBN67 cell proliferation and cytokinesis

scientific article published on October 2002

Isolation and mapping of cDNA hybridization probes specific for ecotropic and nonecotropic murine leukemia proviruses

scientific article published on 01 February 1983

Letters to the editor: Accessibility of 5 S RNA in 50 S ribosomal subunits

scientific article

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

scientific article

Loss of HCF-1-chromatin association precedes temperature-induced growth arrest of tsBN67 cells

scientific article published on June 2001

Mechanism of ribosomal subunit association: discrimination of specific sites in 16 S RNA essential for association activity

scientific article

Monoclonal AKR/J thymic leukemias contain multiple JH immunoglobulin gene rearrangements

scientific article published on December 1983

Multiple regions of TBP participate in the response to transcriptional activators in vivo

scientific article

N-Oct 5 is generated by in vitro proteolysis of the neural POU-domain protein N-Oct 3

scientific article (publication date: 20 March 1997)

Nucleotide sequence of the 3' terminus of E. coli 16S ribosomal RNA.

scientific article

Nucleotide sequence of the 3′ half of AKV ⬇️

scientific article published on November 11, 1982

Nucleotide sequences of accessible regions of 23S RNA in 50S ribosomal subunits

scientific article

O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1

scientific article

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences

scientific article published on 01 November 1988

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter ⬇️

scientific article published on February 21, 1992

Protection of specific sites in 23 S and 5 S RNA from chemical modification by association of 30 S and 50 S ribosomes

scientific article published on June 1979

Proteolysis of HCF-1 by Ser/Thr glycosylation-incompetent O-GlcNAc transferase:UDP-GlcNAc complexes.

scientific article

Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1

scientific article

Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization

scientific article

Role of the HCF-1 basic region in sustaining cell proliferation

scientific article

Role of the inhibitory DNA-binding surface of human TATA-binding protein in recruitment of human TFIIB family members

scientific article

Secondary structure model for 23S ribosomal RNA.

scientific article published on November 1981

Selective use of TBP and TFIIB revealed by a TATA-TBP-TFIIB array with altered specificity

scientific article

Spontaneous reversion of tsBN67 cell proliferation and cytokinesis defects in the absence of HCF-1 function

scientific article

Stabilization but not the transcriptional activity of herpes simplex virus VP16-induced complexes is evolutionarily conserved among HCF family members

scientific article published on December 2001

Structural flexibility in transcription complex formation revealed by protein-DNA photocrosslinking.

scientific article published on August 1997

TAFs: guilt by association?

scientific article published on March 1997

THAP11F80L cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation

scientific article published on 06 January 2020

The HCF repeat is an unusual proteolytic cleavage signal ⬇️

scientific article published on October 15, 1995

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16.

scientific article published in October 1989

The POU domain is a bipartite DNA-binding structure

scientific article published in Nature

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products

scientific article

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

scientific article published on July 1995

The SV40 enhancer contains two distinct levels of organization

scientific article published on May 1988

The SV40 enhancer is composed of multiple functional elements that can compensate for one another

scientific article published on 01 May 1986

The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein

scientific article

The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo

scientific article

The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities

scientific article published in Journal of Biological Chemistry

The gene encoding the VP16-accessory protein HCF (HCFC1) resides in human Xq28 and is highly expressed in fetal tissues and the adult kidney

scientific article published in January 1995

The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1

scientific journal article

The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain

scientific article published in December 1991

The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence

scientific article

The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain

scientific article

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