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List of works by Jean-Pierre Lévesque

38th Annual Meeting of the International Society of Experimental Hematology

scientific article published on December 1, 2009

4 Adhesion molecules in haemopoiesis

scientific article published on September 1, 1997

A niche in a dish: pericytes support HSC.

scientific article published in April 2013

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

scientific article

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1.

scientific article published on 30 October 2003

Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice

scientific article published on 01 February 2019

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

scientific article

CD169(+) macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair.

scientific article published on 22 October 2017

CD169(+) macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

scientific article published on 27 April 2016

CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient-derived strains

scientific article published on 09 May 2019

Cellular players of hematopoietic stem cell mobilization in the bone marrow niche.

scientific article

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2.

scientific article published on 2 May 2019

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells

scientific article published on 01 February 2005

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

scientific article published on 27 April 2020

Engineering a humanized bone organ model in mice to study bone metastases

scientific article published on 2 March 2017

Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis

scientific article published in March 2005

Filling the void: allogeneic myeloid cells for transplantation

scientific article

Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells.

scientific article published in January 2012

Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo

scientific article published on 01 January 2012

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

scientific article published on 21 July 2005

Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

scientific article published on 01 February 2007

Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells

scientific article published in February 2003

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

scientific article published on 01 February 2019

HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

scientific article published on 12 January 2015

HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice.

scientific article published on 17 May 2017

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

scientific article

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation.

scientific article published on 23 January 2012

Hierarchy of immature hematopoietic cells related to blood flow and niche

scientific article published on July 2011

How I treat patients who mobilize hematopoietic stem cells poorly

scientific article (publication date: 27 October 2011)

How we mobilize haemopoietic stem cells.

scientific article published on August 2011

Human Umbilical Cord Blood CD34+Cell Purification with High Yield of Early Progenitors

scientific article published on 01 January 1993

Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.

scientific article published on 29 April 2015

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

scientific article published on 07 March 2019

It takes nerves to recover from chemotherapy

scientific article published on 01 June 2013

Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications

scientific article published on 2 November 2017

Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms.

scientific article published on 27 November 2017

Macrophages and regulation of erythropoiesis

scientific article

Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation

scientific article published in 2021

Mitogenic Effect of Fibrinogen on Hematopoietic Cells: Involvement of Two Distinct Specific Receptors, MFR and ICAM-1

scientific article published on May 8, 1998

Mobilisation strategies for normal and malignant cells.

scientific article published on October 2011

Mobilization of hematopoietic stem cells by depleting bone marrow macrophages

scientific article published on 01 January 2012

Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta

scientific article published in October 2008

N(o)-cadherin role for HSCs

scientific article published on July 12, 2012

Neurogenic heterotopic ossifications develop independently of granulocyte-colony stimulating factor and neutrophils

scientific article published on 22 June 2020

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle.

scientific article published on 26 March 2015

Nichotherapy for stem cells: there goes the neighborhood

scientific article

Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization

scientific article published in 2021

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation.

scientific article published on 14 December 2012

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

scientific article

Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults

scientific article published on September 15, 1993

Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches

scientific article published on 10 August 2016

Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches

scientific article published in 2021

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

scientific article published on 26 June 2018

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization

scientific article

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

scientific article published on 25 February 2022

Targeting the hypoxia-sensing pathway in clinical hematology

scientific article published on 26 December 2013

The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization

scientific article published on 23 September 2010

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.

scientific article published on 12 September 2013

The use of experimental murine models to assess novel agents of hematopoietic stem and progenitor cell mobilization.

scientific article published on June 2008

Tissue engineered humanized bone supports human hematopoiesis in vivo

scientific article

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo

scientific article

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

scientific article published on 21 October 2012

When the Nervous System Turns Skeletal Muscles into Bones: How to Solve the Conundrum of Neurogenic Heterotopic Ossification

scientific article published on 21 October 2020

[E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapy].

scientific article published on 27 March 2013