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List of works by Gregg B Morin

A Tetrahymena intron nucleotide connected to the GTP/arginine site

scientific article

A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.

scientific article

ALEXA: a microarray design platform for alternative expression analysis

article

ARID1A mutations in endometriosis-associated ovarian carcinomas

scientific article

Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma.

scientific article published on 5 March 2015

Alternative expression analysis by RNA sequencing

scientific article published on 12 September 2010

Arginine depletion therapy with ADI-PEG20 limits tumor growth in argininosuccinate synthase deficient ovarian cancer, including small cell carcinoma of the ovary, hypercalcemic type

scientific article published on 14 May 2020

CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion.

scientific article published on 17 March 2017

Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage

scientific article published in February 2013

Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

scientific article published on 01 February 2022

Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers

scientific article

Cytosolic protein interactions of the schizophrenia susceptibility gene dysbindin

scientific article published on 14 March 2010

De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer

scientific article published on 22 July 2021

Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors

scientific article published on 20 August 2018

Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells

scientific article published on 01 April 2003

Evaluating the Characteristics of Reporter Ion Signal Acquired in the Orbitrap Analyzer for Isobaric Mass Tag Proteome Quantification Experiments

scientific article published on 18 April 2017

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

scientific article published on April 1998

Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics

scientific article published on 27 March 2018

Extension of life-span by introduction of telomerase into normal human cells

scientific article

Functional requirement of p23 and Hsp90 in telomerase complexes

scientific journal article

Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma

scientific article published in Nature Communications

Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

scientific article published on 19 September 2018

Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II

scientific article

Investigating Acquisition Performance on the Orbitrap Fusion When Using Tandem MS/MS/MS Scanning with Isobaric Tags.

scientific article published on 18 April 2017

Large-scale mapping of human protein-protein interactions by mass spectrometry

scientific article

MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation

scientific article published on 06 August 2015

Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites

scientific article

Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors

scientific article

PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia.

scientific article published in February 2018

Parsing and Quantification of Raw Orbitrap Mass Spectrometer Data Using RawQuant

scientific article published on 23 April 2018

Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma

publication published on 21 May 2021

Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research

scientific article

Quantitative mass spectrometry reveals changes in SNAP-25 isoforms in schizophrenia.

scientific article

RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management

scientific article published on 03 December 2018

Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

scientific article published in Nature

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

scientific article published in December 1997

Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.

scientific article published on June 2015

Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers

scientific article published on 21 December 2011

Response to Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia"

scientific article published on 01 July 2019

Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress

scientific article published on 4 October 2017

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

scientific article published on 01 January 2019

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

scientific article published on 29 December 2010

Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding

scientific article published on 24 November 2015

Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas

scientific article published on 7 March 2011

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

scientific article

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human ⬇️

scientific article published on August 15, 1997

Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

scientific article published on 27 March 2003

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

scientific article published in February 1999

The 3' overhangs at Tetrahymena thermophila telomeres are packaged by four proteins, Pot1a, Tpt1, Pat1, and Pat2.

scientific article published on 02 December 2013

The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy

scientific article published on 2 April 2015

The Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB

scientific article

The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena.

scientific article

The SNAP25 Interactome in Ventromedial Caudate in Schizophrenia Includes the Mitochondrial Protein ARF1

scientific article published on 02 January 2019

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

scientific article (publication date: 4 April 2012)

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

scientific article

The implications of telomerase biochemistry for human disease ⬇️

scientific article published on April 1, 1997

The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer

scientific article published on 26 June 2019

The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

scientific article published on 13 November 2012

The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors

scientific article

The pathognomonic FOXL2 C134W mutation alters DNA binding specificity

scientific article published on 08 July 2020

Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis

scientific article published in 2024

Using Public Data for Comparative Proteome Analysis in Precision Medicine Programs.

scientific article published on 9 September 2017

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