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List of works by Simon J Powis

A novel instance of class I modification (cim) affecting two of three rat class I RT1-A molecules within one MHC haplotype

scientific journal article

A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules ⬇️

scientific article published on June 4, 1998

Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation

scientific article published on 13 May 2011

An analysis of the antigen binding site of RT1.Aa suggests an allele-specific motif

scientific article published on 01 January 1995

Assembly and export of MHC class I peptide ligands

scientific article (publication date: February 2003)

Biochemical features of HLA-B27 and antigen processing

scientific article published on January 2009

CCCTC-binding factor recruitment to the early region of the human papillomavirus 18 genome regulates viral oncogene expression.

scientific article

CLIP-region mediated interaction of Invariant chain with MHC class I molecules

scientific article published on 27 April 2006

Characterization of the ERp57-Tapasin complex by rapid cellular acidification and thiol modification

scientific article published on August 2003

Cim: an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes

scientific article published on 01 January 1991

Competition for access to the rat major histocompatibility complex class I peptide-loading complex reveals optimization of peptide cargo in the absence of transporter associated with antigen processing (TAP) association

scientific article published on 4 February 2004

Concerted evolution of class I genes in the major histocompatibility complex of murine rodents.

scientific article published on March 1990

Development of a graded index microlens based fiber optical trap and its characterization using principal component analysis

scientific article

Different MHC class I heavy chains compete with each other for folding independently of beta 2-microglobulin and peptide.

scientific article

ERp57 interacts with conserved cysteine residues in the MHC class I peptide-binding groove

scientific article published on 24 April 2007

Editorial: HLA-B27: The Story Continues to Unfold

scientific article published on 8 January 2016

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule

scientific article

Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation

scientific article

Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort.

scientific article published on 17 May 2011

Formation of HLA-B27 homodimers and their relationship to assembly kinetics

scientific article published on 18 December 2003

HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells

scientific article published on June 2000

High-content screening image dataset and quantitative image analysis of Salmonella infected human cells

scientific article published on 16 December 2019

Identification and genetic mapping of Xenopus TAP2 genes.

scientific article

Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells

scientific article

Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits

scientific article

Interactions formed by truncated transporter associated with antigen-processing polypeptides

scientific article published on May 1999

LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes.

scientific article published on August 1995

Label-free optical hemogram of granulocytes enhanced by artificial neural networks

scientific article published on 01 May 2019

Lack of tyrosine 320 impairs spontaneous endocytosis and enhances release of HLA-B27 molecules

scientific article published on March 2006

Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators.

scientific article

Lasing within Live Cells Containing Intracellular Optical Microresonators for Barcode-Type Cell Tagging and Tracking

scientific article published on 17 July 2015

Long-term imaging of cellular forces with high precision by elastic resonator interference stress microscopy.

scientific article published on 19 June 2017

MHC class I dimer formation by alteration of the cellular redox environment and induction of apoptosis

scientific article

Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2 ⬇️

scientific article published on October 1, 1997

Major histocompatibility complex class I-ERp57-tapasin interactions within the peptide-loading complex

scientific article published on 24 April 2007

Major histocompatibility complex-encoded ABC transporters and rat class I peptide motifs

scientific article published on 01 October 1993

Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation

scientific article published on 7 October 2004

Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis

scientific article

Multimodal discrimination of immune cells using a combination of Raman spectroscopy and digital holographic microscopy.

scientific article

Mutational analysis of the oxidoreductase ERp57 reveals the importance of the two central residues in the redox motif

scientific article published on 28 February 2006

Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells.

scientific article

Non-obstructive intracellular nanolasers

scientific article published in Nature Communications

Novel MHC class I structures on exosomes.

scientific article published on 13 July 2009

Novel detection of in vivo HLA-B27 conformations correlates with ankylosing spondylitis association

scientific article

Open conformers: the hidden face of MHC-I molecules

scientific article published on 29 January 2007

Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway.

scientific article published on 18 February 2008

Pathways of antigen processing and presentation.

scientific article

Polymorphisms in the F Pocket of HLA-B27 Subtypes Strongly Affect Assembly, Chaperone Interactions, and Heavy-Chain Misfolding.

scientific article published on 09 October 2016

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

scientific article published on November 1992

Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells: A SWATH-MS study

scientific article published on 13 March 2019

RT1-U: identification of a novel, active, class Ib alloantigen of the rat MHC.

scientific article published on January 1999

Rapid acidification and alkylation: redox analysis of the MHC class I pathway.

scientific article published on 7 October 2008

Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling

scientific article (publication date: 2012)

Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway

scientific article published on 22 January 2014

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

scientific article

Skin colour changes during experimentally-induced sickness

scientific article published on 12 November 2016

Subsets of null and gamma delta T-cell receptor+ T lymphocytes in the blood of young pigs identified by specific monoclonal antibodies

scientific article published on 01 October 1992

Suppression of MHC class I surface expression by calreticulin's P-domain in a calreticulin deficient cell line

scientific article published on 11 March 2010

The MHC Class I heavy chain structurally conserved cysteines 101 and 164 participate in HLA-B27 dimer formation

scientific article

The effect of EHV-1 infection upon circulating leucocyte populations in the natural equine host

scientific article published on 01 October 1993

The major histocompatibility complex class I immunopeptidome of extracellular vesicles

scientific article

The major histocompatibility complex class II-linked cim locus controls the kinetics of intracellular transport of a classical class I molecule

scientific article published on April 1991

The multi-faceted nature of HLA class I dimer molecules

scientific article published on August 2012

The oxidative folding and misfolding of human leukocyte antigen-b27.

scientific article published on 14 June 2011

The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules

scientific article

The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER

scientific article published on 01 February 1996

The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells

scientific article (publication date: 2015)

Three-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysis

scientific journal article

Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene.

scientific article

Two highly divergent ancient allelic lineages of the transporter associated with antigen processing (TAP) gene in Xenopus: further evidence for co-evolution among MHC class I region genes

scientific article published in November 2003

exploits HLA-B27 and host unfolded protein responses to promote intracellular replication

article

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