List of works - David W. Russell

17Beta-hydroxysteroid dehydrogenase 3 deficiency in women

scientific article published on 01 February 1999

17β-Hydroxysteroid dehydrogenase 3 deficiency

scientific article published on 01 May 1996

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

scientific article

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

scientific article published on 15 September 2009

5 alpha-reduced androgens play a key role in murine parturition

scientific article published in April 1996

A comprehensive classification system for lipids

scientific article

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.

scientific article

A mouse macrophage lipidome

scientific article

A rapid and sensitive assay for the detection of eukaryotic ribosome dissociation factors

scientific article published on March 1979

A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

scientific article

Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function

scholarly article

Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages

scientific article published on 17 June 2013

AvaII polymorphism in the human LDL receptor gene

scientific article published on January 1987

Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation

scholarly article

Brain cholesterol turnover required for geranylgeraniol production and learning in mice

scientific article

CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions

scientific article

Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue

scientific article

Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

scientific article

Cholesterol biosynthesis and metabolism

scientific journal article

Clinical importance of the cytochromes P450

scientific article (publication date: 12 October 2002)

Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone

scientific article

De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase

scientific journal article

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1−/−mice fed low levels of cholic acid ⬇️

scientific article published on May 24, 2012

Detecting oxysterols in the human circulation

article

Differential diagnosis in patients with suspected bile acid synthesis defects.

scientific article published on March 2012

Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation

scientific article published in July 1996

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

scientific article published on July 1996

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

scientific article

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding

scientific article published in December 2000

Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor ⬇️

scientific article published on June 1, 1984

Editorial: 25-Hydroxycholesterol: a new life in immunology

scientific article published on December 2010

Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

scientific article published on January 2007

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor

scientific article

Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry

scientific article

Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings.

scientific article

Fetal death in mice lacking 5alpha-reductase type 1 caused by estrogen excess

scientific article published on 01 June 1997

Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency

scientific article

Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase

scientific article

Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels

scientific article

Green light for steroid hormones

scientific article published on April 1996

Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.

scientific article published in December 2002

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

scientific article

Immunohistochemical localization of steroid 5 alpha-reductase 2 in the human male fetal reproductive tract and adult prostate

scientific article

Increased Expression of Early Growth Response-1 Messenger Ribonucleic Acid in Prostatic Adenocarcinoma

article

Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

scientific article published on August 2014

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

scientific article (publication date: 20 June 2003)

LMSD: LIPID MAPS structure database

scientific article

Lipidomics reveals a remarkable diversity of lipids in human plasma ⬇️

scientific article

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

scientific article

Male and female isoenzymes of steroid 5alpha-reductase.

scientific article

Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions

scientific article

Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family

scientific article

Mechanism of action of the wheat germ ribosome dissociation factor: Interaction with the 60 S subunit

scientific article published on 01 May 1980

Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system

scientific article

Molecular genetics of 3beta-hydroxy-Delta5-C27-steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis and liver disease

scientific journal article

Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility

scientific article

Mutation of the CYP2R1 vitamin D 25-hydroxylase in a Saudi Arabian family with severe vitamin D deficiency

scientific article

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain

scientific article

Nuclear orphan receptors control cholesterol catabolism.

scientific article

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

scientific article (publication date: 13 November 2001)

Oxysterol biosynthetic enzymes

scientific article (publication date: 15 December 2000)

Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses

scientific journal article

Purification of eukaryotic cytoplasmic elongation factor 2 and organellar elongation factor G by an affinity binding procedure

scientific article published on November 1979

Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

scientific article

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

scientific article

SRD5A3: A surprising role in glycosylation

scientific article published on July 2010

Subcellular organelle lipidomics in TLR-4-activated macrophages

scientific article

TaqI polymorphism in the human LDL receptor gene

scientific article

The enzymes, regulation, and genetics of bile acid synthesis

scientific article (publication date: 2003)

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

scientific article

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols

scientific article published on 27 September 2001

Two 7 alpha-hydroxylase enzymes in bile acid biosynthesis

scientific article

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1 ⬇️

scientific article published on July 26, 1991

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

scientific article

List of works by David W. Russell

17Beta-hydroxysteroid dehydrogenase 3 deficiency in women

17β-Hydroxysteroid dehydrogenase 3 deficiency

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

5 alpha-reduced androgens play a key role in murine parturition

A comprehensive classification system for lipids

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.

A mouse macrophage lipidome

A rapid and sensitive assay for the detection of eukaryotic ribosome dissociation factors

A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome

Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function

Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages

AvaII polymorphism in the human LDL receptor gene

Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation

Brain cholesterol turnover required for geranylgeraniol production and learning in mice

CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions

Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue

Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

Cholesterol biosynthesis and metabolism

Clinical importance of the cytochromes P450

Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone

De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1−/−mice fed low levels of cholic acid ⬇️

Detecting oxysterols in the human circulation

Differential diagnosis in patients with suspected bile acid synthesis defects.

Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding

Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor ⬇️

Editorial: 25-Hydroxycholesterol: a new life in immunology

Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor

Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry

Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings.

Fetal death in mice lacking 5alpha-reductase type 1 caused by estrogen excess

Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency

Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase

Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels

Green light for steroid hormones

Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

Immunohistochemical localization of steroid 5 alpha-reductase 2 in the human male fetal reproductive tract and adult prostate

Increased Expression of Early Growth Response-1 Messenger Ribonucleic Acid in Prostatic Adenocarcinoma

Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

LMSD: LIPID MAPS structure database

Lipidomics reveals a remarkable diversity of lipids in human plasma ⬇️

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

Male and female isoenzymes of steroid 5alpha-reductase.

Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions

Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family

Mechanism of action of the wheat germ ribosome dissociation factor: Interaction with the 60 S subunit

Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system

Molecular genetics of 3beta-hydroxy-Delta5-C27-steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis and liver disease

Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility

Mutation of the CYP2R1 vitamin D 25-hydroxylase in a Saudi Arabian family with severe vitamin D deficiency

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain

Nuclear orphan receptors control cholesterol catabolism.

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

Oxysterol biosynthetic enzymes

Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses

Purification of eukaryotic cytoplasmic elongation factor 2 and organellar elongation factor G by an affinity binding procedure

Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

SRD5A3: A surprising role in glycosylation

Subcellular organelle lipidomics in TLR-4-activated macrophages

TaqI polymorphism in the human LDL receptor gene

The enzymes, regulation, and genetics of bile acid synthesis

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols

Two 7 alpha-hydroxylase enzymes in bile acid biosynthesis

cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1 ⬇️

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain