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List of works by Triantafyllos Stylianopoulos

A Validated Multiscale In-Silico Model for Mechano-sensitive Tumour Angiogenesis and Growth

scientific article

A simplified approach for the determination of fitting constants in Oliver-Pharr method regarding biological samples

scientific article published on 05 July 2019

A structural, kinetic model of soft tissue thermomechanics.

scientific article

AFM assessing of nanomechanical fingerprints for cancer early diagnosis and classification: from single cell to tissue level

scientific article published on 08 November 2018

Accumulation of mechanical forces in tumors is related to hyaluronan content and tissue stiffness

scientific article

Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis

Alignment of electrospun polymer fibers using a concave collector

scholarly article in RSC Advances, vol. 5 no. 126, 2015

Amphiphilic Polymer Conetworks Based on End-Linked “Core-First” Star Block Copolymers: Structure Formation with Long-Range Order

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

scientific article published on January 2013

Atomic Force Microscopy Probing of Cancer Cells and Tumor Microenvironment Components

article published in 2015

Atomic force microscopy nano-characterization of 3D collagen gels with tunable stiffness.

scientific article published on 22 May 2018

Benefits of vascular normalization are dose and time dependent--letter.

scientific article

Biomechanical modelling of spinal tumour anisotropic growth

scientific article published on 03 June 2020

Biphasic modeling of brain tumor biomechanics and response to radiation treatment

scientific article

Cationic nanoparticles have superior transvascular flux into solid tumors: insights from a mathematical model

scientific article published on 02 August 2012

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

scientific article

Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis

scientific article published on 4 May 2018

Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse

scientific article published on 30 April 2013

Collagen content and extracellular matrix cause cytoskeletal remodelling in pancreatic fibroblasts

scientific article published on 01 May 2019

Combining microenvironment normalization strategies to improve cancer immunotherapy

scientific article published on 03 February 2020

Combining two strategies to improve perfusion and drug delivery in solid tumors

scientific article published on 28 October 2013

Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure

scientific article published on July 2014

Computational predictions of the tensile properties of electrospun fibre meshes: effect of fibre diameter and fibre orientation

scientific article published on 25 January 2008

Coordinated Expression of Ras Suppressor 1 (RSU-1) and Growth Differentiation Factor 15 (GDF15) Affects Glioma Cell Invasion

scientific article published on 13 August 2019

Correction: In-silico dynamic analysis of cytotoxic drug administration to solid tumours: Effect of binding affinity and vessel permeability

Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis

scientific article published on 12 March 2018

Delivering nanomedicine to solid tumors

scientific article

Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies.

scientific article published on January 2011

Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform

scientific article published on 11 July 2019

Design considerations for nanotherapeutics in oncology

scientific article

Design rules for cancer nanomedicines

scholarly article published November 2012

Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment

scientific article published on 12 June 2019

Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation

scientific article

Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions

scientific article

EPR-effect: Utilizing size-dependent Nanoparticle Delivery to Solid Tumors ⬇️

scientific article published on April 1, 2013

Editorial: Metastasis: From Cell Adhesion and Beyond

Evaluation of novel, cationic electrospun microfibrous membranes as adsorbents in bacteria removal

scholarly article in RSC Advances, vol. 5 no. 83, 2015

Evolution of osmotic pressure in solid tumors

scientific article published on 28 September 2014

Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies

scientific article published on 30 January 2019

Experimental measurements and mathematical modeling towards quantification of brain swelling stress

scientific article

Exploring the Nano-Surface of Collagenous and Other Fibrotic Tissues with AFM.

scientific article

Hyaluronan-Derived Swelling of Solid Tumors, the Contribution of Collagen and Cancer Cells, and Implications for Cancer Therapy.

scientific article published on 21 November 2016

ILK silencing inhibits migration and invasion of more invasive glioblastoma cells by downregulating ROCK1 and Fascin-1

scientific article published on 06 June 2020

Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach

scientific article

Image-based biomechanics of collagen-based tissue equivalents

scientific article published on May 2009

Image-based multiscale modeling predicts tissue-level and network-level fiber reorganization in stretched cell-compacted collagen gels

scientific article

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

scientific article published on 07 February 2020

In-silico dynamic analysis of cytotoxic drug administration to solid tumours: Effect of binding affinity and vessel permeability

article

Inhibition of Breast Cancer Cell Invasion by Ras Suppressor-1 (RSU-1) Silencing Is Reversed by Growth Differentiation Factor-15 (GDF-15) ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Intelligent drug delivery systems for the treatment of solid tumors

Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma

scientific article published on 18 January 2019

Mathematical modeling of herpes simplex virus distribution in solid tumors: implications for cancer gene therapy

scientific article

Mechanical properties of structurally-defined magnetoactive polymer (co)networks

scholarly article in RSC Advances, vol. 5 no. 26, 2015

Multiprocess dynamic modeling of tumor evolution with bayesian tumor-specific predictions.

scientific article published on February 2014

Multiscale biphasic modelling of peritumoural collagen microstructure: The effect of tumour growth on permeability and fluid flow.

scientific article published on 13 September 2017

Multiscale computation for bioartificial soft tissues with complex geometries

Multiscale modelling of solid tumour growth: the effect of collagen micromechanics

scientific article published on 12 November 2015

Multiscale, structure-based modeling for the elastic mechanical behavior of arterial walls

scientific article published on August 2007

Multistage nanoparticle delivery system for deep penetration into tumor tissue

scientific article

Multistage nanoparticles for improved delivery into tumor tissue

scientific article published on January 2012

NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression

scientific article published on 11 March 2019

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

scientific article

On the Impact of Chemo-Mechanically Induced Phenotypic Transitions in Gliomas.

scientific article

Permeability calculations in three-dimensional isotropic and oriented fiber networks

scientific article published on 8 December 2008

Pirfenidone normalizes the tumor microenvironment to improve chemotherapy

scientific article

Ras Suppressor-1 (RSU-1) in Cancer Cell Metastasis: Friend or Foe?

scientific article published in January 2017

Ras suppressor-1 (RSU-1) promotes cell invasion in aggressive glioma cells and inhibits it in non-aggressive cells through STAT6 phospho-regulation.

scientific article

Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside

scientific article published on 13 March 2018

Reengineering the Tumor Vasculature: Improving Drug Delivery and Efficacy

scientific article

Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy

scientific article

Remodeling of extracellular matrix due to solid stress accumulation during tumor growth

scientific article

Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients

scientific article published on 16 June 2015

Residual Stresses in Solid Tumors: Implications to Tumor Growth and Drug Delivery

Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)

scientific article

Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors

scientific article

Role of vascular normalization in benefit from metronomic chemotherapy

scientific article published on 7 February 2017

Scaling rules for diffusive drug delivery in tumor and normal tissues

scientific article

Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration

scientific article published on 22 February 2018

Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells

scientific article published in Scientific Reports

Solid tumors are poroelastic solids with a chemo-mechanical feedback on growth

scientific article published on 9 January 2017

Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy.

scientific article

Stress-mediated progression of solid tumors: effect of mechanical stress on tissue oxygenation, cancer cell proliferation, and drug delivery

scientific article published on 13 May 2015

Structurally-defined semi-interpenetrating amphiphilic polymer networks with tunable and predictable mechanical response

scholarly article in RSC Advances, vol. 6 no. 49, 2016

Targeting Inflammation to Improve Tumor Drug Delivery

scientific article published on 23 August 2017

Tensile mechanical properties and hydraulic permeabilities of electrospun cellulose acetate fiber meshes

scientific article published on 09 August 2012

The Solid Mechanics of Cancer and Strategies for Improved Therapy

scientific article

The role of mechanical forces in tumor growth and therapy

scientific article

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging

scientific article

Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors

scientific article published on 11 February 2015

Towards patient-specific modeling of brain tumor growth and formation of secondary nodes guided by DTI-MRI

scientific article published on 31 August 2018

Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner.

scientific article published on 10 April 2017

Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion

article by Andreas Stylianou et al published July 2018 in BBA - General Subjects

Uniaxial and biaxial mechanical behavior of human amnion

article

Vasodilator-Stimulated Phosphoprotein (VASP) depletion from breast cancer MDA-MB-231 cells inhibits tumor spheroid invasion through downregulation of Migfilin, β-catenin and urokinase-plasminogen activator (uPA).

scientific article published on 13 February 2017

Volume-averaging theory for the study of the mechanics of collagen networks

article by Triantafyllos Stylianopoulos & Victor H. Barocas published June 2007 in Computer Methods in Applied Mechanics and Engineering

Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights

scientific article

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