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List of works by Mark D Hulett

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

scientific article published on 16 July 2019

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

scientific article

Access to the Parent Tetrakis(pyridine)gold(III) Trication, Facile Formation of Rare Au(III) Terminal Hydroxides, and Preliminary Studies of Biological Properties

scientific article published in March 2016

Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death

scientific article published on 17 May 2019

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization

scientific article published on 19 September 2016

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer

scholarly article

Cell surface expression of a peptide encoded by the unrearranged TCR-Vbeta8.2 gene.

scientific article published on 28 September 2005

Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation

scientific article published on 11 December 2007

Characterization of FcR Ig-binding sites and epitope mapping

scientific article published on February 1994

Chimeric Fc receptors identify functional domains of the murine high affinity receptor for IgG.

scientific article

Chimeric Fc receptors identify immunoglobulin-binding regions in human Fc gamma RII and Fc epsilon RI.

scientific article

Cloning and characterization of a mouse homologue of the human haematopoietic cell-specific four-transmembrane gene HTm4

scientific journal article

Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences

scientific article published on January 1995

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

scientific article published on January 1996

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

scientific article (publication date: July 1999)

Combating Human Pathogens and Cancer by Targeting Phosphoinositides and Their Metabolism

scientific article published on 31 October 2019

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

scientific article

Convergent evolution of defensin sequence, structure and function ⬇️

scientific article

Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

scientific article

Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.

scientific article published on 24 December 2011

Defining the morphologic features and products of cell disassembly during apoptosis.

scientific article

Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis

scientific article published on 01 December 2019

Determining the contents and cell origins of apoptotic bodies by flow cytometry

scientific article published on 31 October 2017

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

scientific article

Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing.

scientific article published on 8 December 2016

Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two

scientific article published in Journal of Biological Chemistry

Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells.

scientific article

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis

scientific article published on 19 December 2018

Expression of recombinant soluble Fc epsilon RI: function and tissue distribution studies

scientific article published on 01 November 1995

Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1

Fc gamma receptors: gene structure and receptor function

scientific article

Fine Structure Analysis of Interaction of FcεRI with IgE

scientific article published in Journal of Biological Chemistry

Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn2+ in Settings of Tissue Injury

scientific article

Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes

scientific article published on 04 December 2018

Heparanase and the hallmarks of cancer

scientific article published on 30 November 2020

Heparanase: a key enzyme involved in cell invasion

scientific article

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions

scientific article

Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation

scientific article

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake.

scientific article published on 23 June 2010

Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc RI on phagocytes

scientific article published on 13 January 2010

Histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis

scientific article published on 17 August 2005

Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems

scientific article (publication date: April 2005)

Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

scientific article

Human HPA endoglycosidase heparanase. Map position 4q21.3.

scientific article published on 01 January 1999

Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production

scientific article published on 26 February 2011

Human β-defensin 2 kills through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

scientific article published on 25 July 2018

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation.

scientific article published on 9 December 2015

ICAM-1-dependent pathways regulate colonic eosinophilic inflammation

scientific article

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

scientific article (publication date: 26 December 2000)

Identification of residues in the first domain of human Fc alpha receptor essential for interaction with IgA

scientific article published on 01 February 1999

Identification of the IgG binding site of the human low affinity receptor for IgG Fc gamma RII. Enhancement and ablation of binding by site-directed mutagenesis.

scientific article published on May 1994

Identification of the immunoglobulin binding regions (IBR) of Fc gamma RII and Fc epsilon RI.

scientific article

Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process.

scientific article

Importance of phosphoinositide binding by human β-defensin 3 for Akt-dependent cytokine induction

scientific article published on 15 December 2017

Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting

scientific article published on 06 January 2017

Isolation, Tissue Distribution, and Chromosomal Localization of a Novel Testis-Specific Human Four-Transmembrane Gene Related to CD20 and FcϵRI-β

article

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

scientific article published on 29 April 2019

Luminescent iridium(iii) complexes of N-heterocyclic carbene ligands prepared using the 'click reaction'

scientific article published on 01 July 2019

Mapping epitopes of human Fc gamma RII (CDw32) with monoclonal antibodies and recombinant receptors

scientific article published on 01 March 1993

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

scientific article published on 14 February 2014

Molecular basis of Fc receptor function

scientific article published on January 1994

Molecular mechanisms of late apoptotic/necrotic cell clearance

scientific article

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry.

scientific article published on 03 March 2016

Monoclonal antibodies and synthetic peptides define the active site of FcεRI and a potential receptor antagonist

scientific article published on 01 July 2000

Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles

scientific article published on 26 April 2019

Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG.

scientific article

Murine histidine-rich glycoprotein: cloning, characterization and cellular origin

scientific article published in June 2000

Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.

scientific article published on February 2002

NK cell heparanase controls tumor invasion and immune surveillance

scientific article

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties

scientific article

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant ⬇️

scientific article published on 8 August 2016

Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey

article

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

scientific article

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

scientific article published on 11 February 2019

Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein

scientific article

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

scientific article published on 01 November 2019

ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly

scientific article published on 01 May 2019

Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis

scientific article published on 22 February 2012

Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors.

scientific article

Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1

scientific article published in Journal of Biological Chemistry

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage

scientific article

Regulation of mouse Heparanase gene expression in T lymphocytes and tumor cells.

scientific article published on 9 January 2007

Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity

scientific article published in 2023

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

scientific article published on 12 April 2019

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

scientific article

Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis

scientific article published on 20 October 2017

Structural and functional characterization of the membrane-permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis

scientific article published on 22 February 2019

Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

scientific article published on 25 July 2017

Structure of the mouse beta Fc gamma receptor II gene

article

TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis

scientific article published on 05 October 2020

The Defensins Consist of Two Independent, Convergent Protein Superfamilies ⬇️

scientific article published on 13 June 2016

The MS4A family: counting past 1, 2 and 3.

scientific article published on 03 April 2015

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis.

scientific article published on 23 March 2015

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

scientific article published on May 2012

The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells.

scientific article published on 30 March 2017

The phospholipid code: a key component of dying cell recognition, tumor progression and host-microbe interactions

scientific article published on 09 October 2015

The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.

scientific article published on 23 January 2017

The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate ⬇️

scientific article

The relationship between CCR6 and its binding partners: does the CCR6-CCL20 axis have to be extended?

scientific article

The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a

scientific article

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects

scientific article published on 2 August 2017

Use of the 5'-flanking region of the mouse perforin gene to express human Fc gamma receptor I in cytotoxic T lymphocytes

scientific article published on April 1994

X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.

scientific article

Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1.

scientific article published on 9 February 2012

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