List of works - Bradford G. Hill

Aldose reductase (AKR1B) deficiency promotes phagocytosis in bone marrow derived mouse macrophages.

scientific article published on 19 January 2017

Analysis of Stable Isotope Assisted Metabolomics Data Acquired by High Resolution Mass Spectrometry

scientific article

Antiobesogenic role of endothelial nitric oxide synthase.

scientific article published on January 2014

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

scientific article published on 16 August 2011

Autophagic regulation of smooth muscle cell biology

scientific article

Beyond reactive oxygen species: aldehydes as arbitrators of alarm and adaptation

scientific article published on November 2009

Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen

scientific article published in January 2015

Bioenergetic function in cardiovascular cells: the importance of the reserve capacity and its biological regulation

scientific article

Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine

scientific article published on 01 December 2019

CCR7 Maintains Nonresolving Lymph Node and Adipose Inflammation in Obesity

scientific article published on 3 May 2016

Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair

article

Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition

scientific article published on 20 October 2008

Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload.

scientific article published in June 2018

Cardiomyocyte Ogt is essential for postnatal viability.

scientific article

Cardioprotection by N-acetylglucosamine linkage to cellular proteins.

scientific article

Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation

scientific article published on 05 August 2021

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

scientific article

Control of glutamine metabolism by the tumor suppressor Rb.

scientific article published on 28 January 2013

Corrigendum: FVB/NJ Mice Are a Useful Model for Examining Cardiac Adaptations to Treadmill Exercise

scientific article published on 10 October 2017

Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.

scientific article published on 3 November 2017

Distribution based nearest neighbor imputation for truncated high dimensional data with applications to pre-clinical and clinical metabolomics studies

scientific article

Downregulation of CuZn-superoxide dismutase contributes to beta-adrenergic receptor-mediated oxidative stress in the heart

scientific article published on 20 February 2007

Editorial: Mechanisms by Which Acute and Chronic Exercise Promote Cardiometabolic Health

scientific article published on 06 November 2019

Exercise Promotes Resolution of Acute Inflammation by Catecholamine-Mediated Stimulation of Resolvin D1 Biosynthesis

scientific article published on 25 October 2019

Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.

scientific article published on 31 August 2017

FVB/NJ Mice Are a Useful Model for Examining Cardiac Adaptations to Treadmill Exercise.

scientific article published on 21 December 2016

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.

scientific article published on 13 July 2015

Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis

scientific article published on 28 August 2018

High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation.

scientific article published on April 2015

High throughput measurement of metabolism in planarians reveals activation of glycolysis during regeneration.

scientific article

Identification of a plasma metabolomic signature of thrombotic myocardial infarction that is distinct from non-thrombotic myocardial infarction and stable coronary artery disease

scientific article

Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice

scientific article

Implications of autophagy for vascular smooth muscle cell function and plasticity

scientific article

Insights into metabolic remodeling of the hypertrophic and failing myocardium

scientific article published on November 2014

Integration of cellular bioenergetics with mitochondrial quality control and autophagy

scientific article published on December 2012

Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation

scientific article published on 23 September 2019

Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes

scientific article published on 13 July 2017

Lipid peroxidation product 4-hydroxy-trans-2-nonenal causes endothelial activation by inducing endoplasmic reticulum stress

scientific article published on 6 January 2012

Measurement and identification of S-glutathiolated proteins.

scientific article

Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure

scientific article

Metabolic Coordination of Physiological and Pathological Cardiac Remodeling

scientific article published on 01 June 2018

Metabolic Mechanisms of Exercise-Induced Cardiac Remodeling

scientific article published on 11 September 2018

Metabolic remodeling of white adipose tissue in obesity

scientific article

Metabolomic analysis of pressure-overloaded and infarcted mouse hearts

scientific article

Methods for imaging and detecting modification of proteins by reactive lipid species

scientific article published on 14 May 2009

Methods for the determination and quantification of the reactive thiol proteome.

scientific article

Mitochondria-associated lactate dehydrogenase is not a biologically significant contributor to bioenergetic function in murine striated muscle

scientific article published on 22 March 2019

Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

scientific article published on 04 October 2019

Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation.

scientific article

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

scientific article

Myocardial ischaemia inhibits mitochondrial metabolism of 4-hydroxy-trans-2-nonenal.

scientific article

Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells.

scientific article published on 08 August 2016

O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells

scientific article published on 13 November 2015

Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype

scientific article published on 14 August 2012

Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response

scientific article published on 26 January 2013

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

scientific article

Physiological Biomimetic Culture System for Pig and Human Heart Slices

scientific article published on 16 July 2019

Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells

scientific article

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system.

scientific article

Protein S-glutathiolation: redox-sensitive regulation of protein function.

scientific article published on 20 July 2011

Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification

scientific article

Quercetin prevents left ventricular hypertrophy in the Apo E knockout mouse

scientific article published on 16 July 2013

Recent advances in mitochondrial research

scientific article

Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.

scientific article

Regulation of obesity and insulin resistance by nitric oxide

scientific article

Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation

scientific article

Responses of hypertrophied myocytes to reactive species: implications for glycolysis and electrophile metabolism

scientific article

Role of glutathiolation in preservation, restoration and regulation of protein function.

scientific article

S-nitrosation and thiol switching in the mitochondrion: a new paradigm for cardioprotection in ischaemic preconditioning.

scientific article published in June 2008

Standardized bioenergetic profiling of adult mouse cardiomyocytes.

scientific article published on 23 October 2012

Systems characterization of differential plasma metabolome perturbations following thrombotic and non-thrombotic myocardial infarction.

scientific article published on 21 March 2017

TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity.

scientific article published on 08 July 2013

Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells

scientific article published in March 2008

Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

scientific article published on 23 August 2012

Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice.

scientific article published on 08 March 2016

What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.

scientific article

List of works by Bradford G. Hill

Aldose reductase (AKR1B) deficiency promotes phagocytosis in bone marrow derived mouse macrophages.

Analysis of Stable Isotope Assisted Metabolomics Data Acquired by High Resolution Mass Spectrometry

Antiobesogenic role of endothelial nitric oxide synthase.

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

Autophagic regulation of smooth muscle cell biology

Beyond reactive oxygen species: aldehydes as arbitrators of alarm and adaptation

Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen

Bioenergetic function in cardiovascular cells: the importance of the reserve capacity and its biological regulation

Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine

CCR7 Maintains Nonresolving Lymph Node and Adipose Inflammation in Obesity

Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair

Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition

Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload.

Cardiomyocyte Ogt is essential for postnatal viability.

Cardioprotection by N-acetylglucosamine linkage to cellular proteins.

Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

Control of glutamine metabolism by the tumor suppressor Rb.

Corrigendum: FVB/NJ Mice Are a Useful Model for Examining Cardiac Adaptations to Treadmill Exercise

Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.

Distribution based nearest neighbor imputation for truncated high dimensional data with applications to pre-clinical and clinical metabolomics studies

Downregulation of CuZn-superoxide dismutase contributes to beta-adrenergic receptor-mediated oxidative stress in the heart

Editorial: Mechanisms by Which Acute and Chronic Exercise Promote Cardiometabolic Health

Exercise Promotes Resolution of Acute Inflammation by Catecholamine-Mediated Stimulation of Resolvin D1 Biosynthesis

Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.

FVB/NJ Mice Are a Useful Model for Examining Cardiac Adaptations to Treadmill Exercise.

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.

Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis

High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation.

High throughput measurement of metabolism in planarians reveals activation of glycolysis during regeneration.

Identification of a plasma metabolomic signature of thrombotic myocardial infarction that is distinct from non-thrombotic myocardial infarction and stable coronary artery disease

Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice

Implications of autophagy for vascular smooth muscle cell function and plasticity

Insights into metabolic remodeling of the hypertrophic and failing myocardium

Integration of cellular bioenergetics with mitochondrial quality control and autophagy

Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation

Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes

Lipid peroxidation product 4-hydroxy-trans-2-nonenal causes endothelial activation by inducing endoplasmic reticulum stress

Measurement and identification of S-glutathiolated proteins.

Mechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure

Metabolic Coordination of Physiological and Pathological Cardiac Remodeling

Metabolic Mechanisms of Exercise-Induced Cardiac Remodeling

Metabolic remodeling of white adipose tissue in obesity

Metabolomic analysis of pressure-overloaded and infarcted mouse hearts

Methods for imaging and detecting modification of proteins by reactive lipid species

Methods for the determination and quantification of the reactive thiol proteome.

Mitochondria-associated lactate dehydrogenase is not a biologically significant contributor to bioenergetic function in murine striated muscle

Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation.

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

Myocardial ischaemia inhibits mitochondrial metabolism of 4-hydroxy-trans-2-nonenal.

Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells.

O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells

Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype

Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

Physiological Biomimetic Culture System for Pig and Human Heart Slices

Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system.

Protein S-glutathiolation: redox-sensitive regulation of protein function.

Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification

Quercetin prevents left ventricular hypertrophy in the Apo E knockout mouse

Recent advances in mitochondrial research

Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.

Regulation of obesity and insulin resistance by nitric oxide

Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation

Responses of hypertrophied myocytes to reactive species: implications for glycolysis and electrophile metabolism

Role of glutathiolation in preservation, restoration and regulation of protein function.

S-nitrosation and thiol switching in the mitochondrion: a new paradigm for cardioprotection in ischaemic preconditioning.

Standardized bioenergetic profiling of adult mouse cardiomyocytes.

Systems characterization of differential plasma metabolome perturbations following thrombotic and non-thrombotic myocardial infarction.

TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity.

Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells

Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice.

What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.