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List of works by Yong-Keun Jung

AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.

scientific article published on 21 October 2007

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.

scientific article published on March 2016

Alternative Cleavage of Alzheimer-Associated Presenilins During Apoptosis by a Caspase-3 Family Protease ⬇️

scientific article (publication date: 18 July 1997)

Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease

scientific article

Amyloid β-induced FOXRED2 mediates neuronal cell death via inhibition of proteasome activity

scientific article published on 23 October 2010

Atypical role of proximal caspase-8 in truncated Tau-induced neurite regression and neuronal cell death

scientific article published on December 2003

Autophagy in neurodegenerative diseases: from mechanism to therapeutic approach

scientific article

Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis

scientific article published on 6 April 2010

Calcium binding of ARC mediates regulation of caspase 8 and cell death

scientific article

Calpeptin suppresses tumor necrosis factor-alpha-induced death and accumulation of p53 in L929 mouse sarcoma cells

scientific article published in April 2002

Calsenilin contributes to neuronal cell death in ischemic stroke.

scientific article published on 27 December 2012

Caspase cleavage product lacking amino-terminus of IkappaBalpha sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis

scientific article

Characterization and comparative genomic analysis of intronless Adams with testicular gene expression.

scientific article published in April 2004

Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3.

scientific article

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15 ⬇️

scientific article published on June 18, 2012

Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2.

scientific article

Contribution of presenilin/gamma-secretase to calsenilin-mediated apoptosis.

scientific article published in May 2003

Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors

scientific article published on 23 February 2010

Down-regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia

scientific journal article

E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity

scientific journal article

ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress.

scientific article published on 5 December 2015

Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity

scientific article published in September 2003

Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition.

scientific article published on 27 April 2015

Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death

scientific article (publication date: 27 May 2005)

Expression of the carboxypeptidase E gene: characterization of the initiator-binding proteins

scientific article published on January 1994

FKBP8 LIRL-dependent mitochondrial fragmentation facilitates mitophagy under stress conditions

scientific article published on 26 December 2019

Fas- and tumor necrosis factor-mediated apoptosis uses the same binding surface of FADD to trigger signal transduction. A typical model for convergent signal transduction

scientific article published on November 2000

Fas-associated factor 1, FAF1, is a member of Fas death-inducing signaling complex

scientific article

FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease

scientific article

FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

scientific article published on 27 September 2011

Identification and characterization of ADAM32 with testis-predominant gene expression.

scientific article published on January 2003

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

scientific article published in August 1996

Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells.

scientific article

Identification of glucose-6-phosphate transporter as a key regulator functioning at the autophagy initiation step

scientific article published on 15 May 2015

Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis

scientific journal article

Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure

scientific article

Intracellular cleavage of osteopontin by caspase-8 modulates hypoxia/reoxygenation cell death through p53.

scientific article published on 19 August 2009

Lithium rescues the impaired autophagy process in CbCln3(Δex7/8/Δex7/8) cerebellar cells and reduces neuronal vulnerability to cell death via IMPase inhibition.

scientific article published on 19 January 2011

Mechanism of cyclosporine-induced overgrowth in gingiva

scientific article published on 01 June 2006

Molecules and their functions in autophagy ⬇️

scientific article published on February 29, 2012

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

scientific article published in February 1998

Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin

scientific journal article

Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.

scientific article

Overexpression of calsenilin enhances gamma-secretase activity.

scientific article

Peroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase.

scientific article

Pimozide reduces toxic forms of tau in TauC3 mice via 5' adenosine monophosphate-activated protein kinase-mediated autophagy

scientific article published on 20 June 2017

Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation

scientific article published on 26 September 2006

Potentiation of Fas- and TRAIL-mediated apoptosis by IFN-gamma in A549 lung epithelial cells: enhancement of caspase-8 expression through IFN-response element.

scientific article published in December 2002

Proapoptotic effects of tau cleavage product generated by caspase-3.

scientific article

Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice

scientific journal article

Pyruvate stimulates mitophagy via PINK1 stabilization.

scientific article published on 9 June 2015

Reconstitution of caspase-8 sensitizes JB6 cells to TRAIL

scientific article published on 01 October 2000

Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients

scientific article (publication date: 3 April 2003)

Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cells

scientific article

Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling

scientific article

Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes.

scientific article published on 23 August 2012

SERP1 is an assembly regulator of γ-secretase in metabolic stress conditions

scientific article published on 17 March 2020

Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines

scientific article published on 22 April 2010

Selenite negatively regulates caspase-3 through a redox mechanism

scientific article published on 01 March 2000

Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity

scientific article

Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme

scientific article

Suppression of hypoxic cell death by APIP-induced sustained activation of AKT and ERK1/2

scientific journal article

Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor

scientific article published on March 1996

Suppression of receptor-mediated apoptosis by death effecter domain recruiting domain binding peptide aptamer

scientific article

Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons

scientific article published on 01 June 2000

TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease

scientific article published on 05 September 2018

The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth

scientific article published on January 2014

The Interplay between Autophagy and Aging

scientific article published on October 2013

The involvement of oxidative stress in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in HeLa cells

scientific article published in August 2002

The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β

scientific article

Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex

scientific article published in January 2004

iRhom1 regulates proteasome activity via PAC1/2 under ER stress

scientific article published on 25 June 2015

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