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List of works by Sanna Lehtonen

CD2AP is associated with end-stage renal disease in patients with type 1 diabetes

scientific article published on 17 May 2013

Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex

scientific journal article

Cold Saline Perfusion before Ischemia-Reperfusion Is Harmful to the Kidney and Is Associated with the Loss of Ezrin, a Cytoskeletal Protein, in Rats

scientific article published on 03 January 2021

Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex

scientific article published in April 2008

Cyclin-dependent kinase 2 protects podocytes from apoptosis

scientific article published on 15 February 2016

Densin and beta-catenin form a complex and co-localize in cultured podocyte cell junctions.

scientific article

Early-onset diabetic E1-DN mice develop albuminuria and glomerular injury typical of diabetic nephropathy.

scientific article published on 27 April 2015

Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice

scientific article published on 14 February 2022

Editorial: Podocyte Pathology and Nephropathy-An Update

scientific article published on 30 July 2019

Expression of toll-like receptors in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma--an in vivo and in vitro study.

scientific article published on 5 May 2015

Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes

scientific article published on March 2014

Glucose Transporters in Diabetic Kidney Disease-Friends or Foes?

scientific article published on 9 April 2018

INPPL1is associated with the metabolic syndrome in men with Type 1 diabetes, but not with diabetic nephropathy

scientific article published on 01 December 2012

Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis

scientific article published on 6 September 2017

Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line

scientific article

Lack of CD2AP disrupts Glut4 trafficking and attenuates glucose uptake in podocytes.

scientific article published on 6 November 2015

Metformin Protects against Podocyte Injury in Diabetic Kidney Disease

scientific article published on 10 December 2020

Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity

scientific article published on 15 October 2018

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

scientific journal article

Neph3 associates with regulation of glomerular and neural development in zebrafish

scientific article published on 6 October 2011

Nephrin TRAP Mice Lack Slit Diaphragms and Show Fibrotic Glomeruli and Cystic Tubular Lesions

scientific article published on 01 June 2002

Nephrin Trafficking beyond the Kidney--Role in Glucose-Stimulated Insulin Secretion in β Cells

scientific article published on 23 September 2015

Novel Sulfonanilide Inhibitors of SHIP2 Enhance Glucose Uptake into Cultured Myotubes

scientific article published on 14 January 2020

Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility

scientific article published on 30 October 2015

PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.

scientific article published on 26 May 2017

Predictive role of toll-like receptors 2, 4, and 9 in oral tongue squamous cell carcinoma

scientific article published on 26 September 2014

Regulation of Neph3 gene in podocytes--key roles of transcription factors NF-kappaB and Sp1.

scientific article published on 24 August 2009

Regulation of nephrin gene by the Ets transcription factor, GA-binding protein

article

Report of the Second European Zebrafish Principal Investigator Meeting in Karlsruhe, Germany, March 21-24, 2012.

scientific article published on 26 March 2013

SHIPping out diabetes-Metformin, an old friend among new SHIP2 inhibitors

scientific article published on 12 August 2019

Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis

scientific article

Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish

scientific article published on 24 March 2017

Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

scientific article published on 20 December 2016

Septins in kidney: A territory little explored

scientific article published on 17 August 2018

Sticklebacks adapted to divergent osmotic environments show differences in plasticity for kidney morphology and candidate gene expression

scientific article

Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7

scientific article

Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.

scientific article published on 21 July 2016

Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice

scientific article published on 21 April 2020

Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae

scientific article published on 13 July 2015

The R-Ras interaction partner ORP3 regulates cell adhesion

scientific article published on 12 February 2008

The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis.

scientific article

Toll-like receptors 2, 4, and 9 in primary, metastasized, and recurrent oral tongue squamous cell carcinomas

scientific article published on October 2015

Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin

scientific journal article

Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.

scientific article

Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations

scientific article published on 04 January 2021

sept7b is required for the differentiation of pancreatic endocrine progenitors.

scientific article published on 26 April 2016