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List of works by Josef Köhrle

3,5-Diiodo-L-thyronine (3,5-t2) exerts thyromimetic effects on hypothalamus-pituitary-thyroid axis, body composition, and energy metabolism in male diet-induced obese mice.

scientific article

3,5-T2 alters murine genes relevant for xenobiotic, steroid, and thyroid hormone metabolism

scientific article published on 22 February 2016

3,5-T2-A Janus-Faced Thyroid Hormone Metabolite Exerts Both Canonical T3-Mimetic Endocrine and Intracrine Hepatic Action

scientific article published on 01 January 2019

3,5-diiodo-L-thyronine stimulates type 1 5'deiodinase activity in rat anterior pituitaries in vivo and in reaggregate cultures and GH3 cells in vitro

scientific article published on August 1997

3-Iodothyronamine Decreases Expression of Genes Involved in Iodide Metabolism in Mouse Thyroids and Inhibits Iodide Uptake in PCCL3 Thyrocytes

scientific article published on 27 October 2016

3-Iodothyronamine increases transient receptor potential melastatin channel 8 (TRPM8) activity in immortalized human corneal epithelial cells.

scientific article published on 9 December 2015

3-Iodothyronamine reduces insulin secretion in vitro via a mitochondrial mechanism

scientific article

3-Iodothyronamine-A Thyroid Hormone Metabolite With Distinct Target Profiles and Mode of Action

scientific article published on 01 April 2019

3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling

scientific article

5'-Deiodination in rat hepatocytes: effects of specific flavonoid inhibitors

scientific article published in March 1990

55th Mosbach Colloquium: how nutrients influence gene activity

scientific article

A Nonradioactive DEHAL Assay for Testing Substrates, Inhibitors, and Monitoring Endogenous Activity

scientific article published on 12 October 2016

A Nonradioactive Uptake Assay for Rapid Analysis of Thyroid Hormone Transporter Function

scientific article published on 24 April 2015

A Thyroid Hormone-Independent Molecular Fingerprint of 3,5-Diiodothyronine Suggests a Strong Relationship with Coffee Metabolism in Humans

scientific article published on 11 November 2019

A combined LC-MS/MS and LC-MS3 multi-method for the quantification of iodothyronines in human blood serum

scientific article published on 15 June 2019

A validated LC-MS/MS method for cellular thyroid hormone metabolism: Uptake and turnover of mono-iodinated thyroid hormone metabolites by PCCL3 thyrocytes

scientific article published on 24 August 2017

Abstracts and short papers from the 5th Congress of the Polish Thyroid Association, Poznan, 3-5 September, 2015: Poznan, Poland. 3-5 September 2015.

scientific article published on 6 December 2016

Affinity labeling of rat liver and kidney type I 5'-deiodinase. Identification of the 27-kDa substrate binding subunit

scientific article published on 01 April 1990

Aging Alters Phenotypic Traits of Thyroid Dysfunction in Male Mice With Divergent Effects on Complex Systems but Preserved Thyroid Hormone Action in Target Organs

scientific article published on 01 July 2019

Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8.

scientific article

Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P.

scientific article

An Improved Nonradioactive Screening Method Identifies Genistein and Xanthohumol as Potent Inhibitors of Iodothyronine Deiodinases

scientific article published on 25 June 2015

Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile

scientific article

Antihormonal effects of plant extracts: iodothyronine deiodinase of rat liver is inhibited by extracts and secondary metabolites of plants

scientific article published on April 1984

Association between 3-Iodothyronamine (T1AM) Concentrations and Left Ventricular Function in Chronic Heart Failure

scientific article published on 01 April 2019

Autoantibodies to the IGF1 receptor in Graves' orbitopathy

scientific article published on 21 December 2012

Autoregulation of 3, 3',5'-triiodothyronine production by rat liver microsomes

scientific article published on 01 October 1981

Avoiding the pitfalls when quantifying thyroid hormones and their metabolites using mass spectrometric methods: The role of quality assurance

scientific article published on 30 January 2017

BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.

scientific article published on 8 December 2017

Binding of thyroxine to pig transthyretin, its cDNA structure, and other properties

scientific article

Biochemical characteristics of iodothyronine monodeiodination by rat liver microsomes: the interaction between iodothyronine substrate analogs and the ligand binding site of the iodothyronine deiodinase resembles that of the TBPA-iodothyronine ligan

scientific article published on 01 January 1984

Biochemistry of iodothyronine deiodination.

scientific article published on January 1988

Biosynthesis of 3-Iodothyronamine From T4 in Murine Intestinal Tissue

scientific article published on 8 September 2015

Bone turnover and bone mineral density are independently related to selenium status in healthy euthyroid postmenopausal women

scientific article published on 17 August 2012

CD82, and CD63 in thyroid cancer.

scientific article

Canonical TSH Regulation of Cathepsin-Mediated Thyroglobulin Processing in the Thyroid Gland of Male Mice Requires Taar1 Expression.

scientific article published on 20 March 2018

Cell differentiation and local regulatory systems

scientific article

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

scientific article published on 6 October 2016

Chronic Kidney Disease Distinctly Affects Relationship Between Selenoprotein P Status and Serum Thyroid Hormone Parameters

scientific article published on 8 September 2015

Circadian and pulsatile thyrotropin secretion in euthyroid man under the influence of thyroid hormone and glucocorticoid administration

scientific article published in July 1987

Circulating 3-T1AM and 3,5-T2 in Critically Ill Patients: A Cross-Sectional Observational Study

scientific article

Circulating levels of peroxiredoxin 4 as a novel biomarker of oxidative stress in patients with sepsis

scientific article published on 01 May 2011

Clinical impact of retinoids in redifferentiation therapy of advanced thyroid cancer: final results of a pilot study

scientific article published on 13 March 2002

Cloning and characterization of the human selenoprotein P promoter. Response of selenoprotein P expression to cytokines in liver cells.

scientific article published on November 1997

Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture

scientific article published on 28 December 2010

Consensus statement on lung cancer. Lung Cancer Panel

scientific article published on August 1997

Contribution of interleukin-12 to the pathogenesis of non-thyroidal illness

scientific article published in February 2004

Conversion of T3 and rT3 to 3,3'-T2: pH dependency

scientific article

Copeptin and Peroxiredoxin-4 Independently Predict Mortality in Patients With Nonspecific Complaints Presenting to the Emergency Department

scientific article published on 01 August 2011

Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism

scientific article

Detection of 3,5-diiodothyronine in sera of patients with altered thyroid status using a new monoclonal antibody-based chemiluminescence immunoassay

article

Detection of stable N-terminal protachykinin A immunoreactivity in human plasma and cerebrospinal fluid

scientific article published on 19 February 2008

Development of a validated liquid chromatography/tandem mass spectrometry method for the distinction of thyronine and thyronamine constitutional isomers and for the identification of new deiodinase substrates

scientific article published in October 2008

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells

scientific article published on 29 December 2010

Developmentally regulated thyroid hormone distributor proteins in marsupials, a reptile, and fish.

scientific article published on 13 January 2005

Differences in Mouse Hepatic Thyroid Hormone Transporter Expression with Age and Hyperthyroidism

scientific article published on 27 May 2015

Different tissue distribution, elimination, and kinetics of thyroxine and its conformational analog, the synthetic flavonoid EMD 49209 in the rat

scientific article published on 01 January 1997

Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists

scientific article published in 2011

Differential selenium-dependent expression of type I 5'-deiodinase and glutathione peroxidase in the porcine epithelial kidney cell line LLC-PK1.

scientific article published on March 1995

Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis?

scientific article published on 28 October 2011

Down-regulation of the hepatic selenoprotein biosynthesis machinery impairs selenium metabolism during the acute phase response in mice

scientific article published on 9 January 2009

Early adaptation of thyrotropin and thyroglobulin secretion to experimentally decreased iodine supply in man.

scientific article

Editorial: Get inspired - Lessons learned from evolution of thyroid hormone signaling in developmental processes.

scientific article published in December 2017

Effect of biological alterations of type I 5'deiodinase activity on affinity labeled membrane proteins in rat liver and kidney

scientific article published in February 1990

Effect of mutations of the human serpin protein corticosteroid-binding globulin on cortisol-binding, thermal and protease sensitivity

scientific article published on 11 March 2010

Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid function in rats

scientific article

Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation

scientific article published on 21 August 2018

Effects of proinflammatory cytokines on anterior pituitary 5'-deiodinase type I and type II.

scientific article

Effects of retinoids and role of retinoic acid receptors in human thyroid carcinomas and cell lines derived therefrom

scientific article

Efficacy of protocols for induction of chronic hyperthyroidism in male and female mice

scientific article published on 29 July 2016

Efficient selenium transfer from mother to offspring in selenoprotein-P-deficient mice enables dose-dependent rescue of phenotypes associated with selenium deficiency

scientific journal article

Endocrine active compounds affect thyrotropin and thyroid hormone levels in serum as well as endpoints of thyroid hormone action in liver, heart and kidney

scientific article published in December 2004

Endocrine disruptors and the thyroid gland--a combined in vitro and in vivo analysis of potential new biomarkers

scientific article

Endocrine, Metabolic and Pharmacological Effects of Thyronamines (TAM), Thyroacetic Acids (TA) and Thyroid Hormone Metabolites (THM) - Evidence from in vitro, Cellular, Experimental Animal and Human Studies

scientific article published on 25 May 2020

Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8.

scientific article published on 13 July 2010

Establishment of an Effective Radioiodide Thyroid Ablation Protocol in Mice

scientific article published on 23 May 2015

European Consensus Statement on Lung Cancer: risk factors and prevention. Lung Cancer Panel ⬇️

scientific article published on May 1, 1998

Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: a national toxicology program workshop review

scientific article

Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay

scientific article published on 13 April 2011

Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action

scientific article published on 23 February 2016

Expression and regulation of aromatase cytochrome P450 in THP 1 human myeloid leukaemia cells

scientific article published on 01 April 1995

Expression of iodothyronine deiodinase in cultured thyroid cells

scientific article published in May 1991

Expression of selenoproteins in various rat and human tissues and cell lines

scientific article published on June 1997

Expression pattern of gastrointestinal selenoproteins--targets for selenium supplementation.

scientific article

Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis

scientific article

Factors impacting the aminoglycoside-induced UGA stop codon readthrough in selenoprotein translation

scientific article published on 26 April 2016

Few Amino Acid Exchanges Expand the Substrate Spectrum of Monocarboxylate Transporter 10

scientific article published on 31 May 2016

Flavonoid Administration Immediately Displaces Thyroxine (T4) from Serum Transthyretin, Increases Serum Free T4, and Decreases Serum Thyrotropin in the Rat*

scientific article published on 01 June 1990

Flavonoid effects on transport, metabolism and action of thyroid hormones

scientific article

Free-flow isoelectric focusing of proteins remaining in cell fragments following sonication of thyroid carcinoma cells

scientific article

Function of thyroid hormone transporters in the central nervous system ⬇️

scientific article published on 07 August 2012

Functional retinoid and thyroid hormone receptors in human thyroid-carcinoma cell lines and tissues.

scientific article published on May 1998

Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues

scientific article published on March 2003

Genistein and other soya isoflavones are potent ligands for transthyretin in serum and cerebrospinal fluid

scientific article published on June 2006

Glutathione peroxidase isoforms as part of the local antioxidative defense system in normal and Barrett's esophagus

scientific article published in June 2003

Guard your master: thyroid hormone receptors protect their gland of origin from thyroid cancer

scientific article published on 01 October 2004

Hepatic deiodinase activity is dispensable for the maintenance of normal circulating thyroid hormone levels in mice

scientific article

Hepatic metabolite profiles in mice with a suboptimal selenium status

scientific article

Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice

scientific article published in February 2008

Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply

scientific article published on March 2005

High T3, Low T4 Serum Levels in Mct8 Deficiency Are Not Caused by Increased Hepatic Conversion through Type I Deiodinase

scientific article published on 23 May 2015

High Variability of Insulin Sensitivity in Closely Related Obese Mouse Inbred Strains

scientific article published on 20 July 2016

High levels of thyroid-stimulating hormone are associated with aortic wall thickness in the general population

scientific article

High serum thyrotropin levels are associated with retinal arteriolar narrowing in the general population

scientific article

Hormone des Hypothalamus und der Hypophyse

Human thyroid carcinoma cell lines show different retinoic acid receptor repertoires and retinoid responses

scientific article published on April 2004

Human thyrotropin receptor gene: expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation

scientific article published on 01 November 1991

Hyperthyroidism and Hypothyroidism in Male Mice and Their Effects on Bone Mass, Bone Turnover, and the Wnt Inhibitors Sclerostin and Dickkopf-1.

scientific article published on 28 July 2015

Identification by differential display PCR of the selenoprotein thioredoxin reductase as a 1 alpha,25(OH)2-vitamin D3-responsive gene in human osteoblasts--regulation by selenite

scientific article published in January 1998

Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-beta ⬇️

scientific article

Identification of iopanoic acid as substrate of type 1 deiodinase by a novel nonradioactive iodide-release assay.

scientific article

Identification of type I iodothyronine 5'-deiodinase as a selenoenzyme

scientific article published on 01 December 1990

Igniting stage two in Endocrine Connections

scientific article published on May 2017

Immunoluminometric assay for quantification of peroxiredoxin 4 in human serum

scientific article published on 20 May 2010

Implications of the molecular characterization of the sodium-iodide symporter (NIS)

article

In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice

scientific article published on 5 December 2017

In vivo effects of flavonoid EMD 21388 on thyroid hormone secretion and metabolism in rats

scientific article published in August 1991

Increased risk of thyroid pathology in patients with thyroid hemiagenesis: results of a large cohort case-control study

scientific article published on 21 October 2009

Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia

scientific article published on 9 July 2012

Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

scientific article

Interference of endocrine disrupters with thyroid hormone receptor-dependent transactivation

scientific article published on 29 April 2009

Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5

scientific article

Inverse mRNA expression of the selenocysteine-containing proteins GI-GPx and SeP in colorectal adenomas compared with adjacent normal mucosa

scientific article published on 01 January 2000

Involvement of the L-Type Amino Acid Transporter Lat2 in the Transport of 3,3'-Diiodothyronine across the Plasma Membrane

scientific article published on 28 May 2015

Iodothyronine deiodinases

scientific article (publication date: 2002)

LC-MS/MS detection of thyroid hormone metabolites in tissue samples

scientific article published on 01 September 2012

Lack of the Thyroid Hormone Transporter Mct8 in Osteoblast and Osteoclast Progenitors Increases Trabecular Bone in Male Mice

scientific article published on 31 January 2020

Letter Re: Id1 gene expression in hyperplastic and neoplastic thyroid tissues

scientific article published on 01 October 2005

Local estradiol metabolism in osteoblast- and osteoclast-like cells

scientific article published on April 1997

Mass Spectrometry-Based Determination of Thyroid Hormones and Their Metabolites in Endocrine Diagnostics and Biomedical Research - Implications for Human Serum Diagnostics

scientific article published on 16 June 2020

Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals

scientific article published on 27 February 2013

Metabolism of the thyroid hormones with respect to cytoprotection

scientific article published on 01 January 1986

Midregional Proenkephalin A and N-terminal Protachykinin A are decreased in the cerebrospinal fluid of patients with dementia disorders and acute neuroinflammation

scientific article published on 5 March 2010

Minireview: Insights Into the Structural and Molecular Consequences of the TSH-β Mutation C105Vfs114X.

scientific article

Modulation of selenoprotein P expression by TGF-beta(1) is mediated by Smad proteins

scientific article

Molecular features of the L-type amino acid transporter 2 determine different import and export profiles for thyroid hormones and amino acids

scientific article published on 17 January 2017

Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy

scientific article published on 3 August 2011

Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain

scientific article published on October 2010

Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome. ⬇️

scientific article published in July 2009

Neuronal and ependymal expression of selenoprotein P in the human brain

scientific article published on 25 January 2007

Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

scientific journal article

New assay for the measurement of selenoprotein P as a sepsis biomarker from serum

scientific article published on 29 January 2008

Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.

scientific article published on 11 December 2017

Nonthyroidal Illness Syndrome in Cardiac Illness Involves Elevated Concentrations of 3,5-Diiodothyronine and Correlates with Atrial Remodeling

scientific article

Orchidectomy of middle-aged rats decreases liver deiodinase 1 and pituitary deiodinase 2 activity.

scientific article published on 6 September 2012

P1, P5-Bis-(5'-adenosyl)pentaphosphate: is this adenylate kinase inhibitor substrate for mitochondrial processes?

scientific article

Pathophysiological relevance of selenium

scientific article

Peroxides and peroxide-degrading enzymes in the thyroid

scientific article published on September 2008

Plasma Bile Acids Are Associated with Energy Expenditure and Thyroid Function in Humans

scientific article published on 07 December 2011

Proenkephalin A 119-159, a stable proenkephalin A precursor fragment identified in human circulation

scientific article published on 18 April 2006

Proinflammatory cytokines inhibit the expression and function of human type I 5'-deiodinase in HepG2 hepatocarcinoma cells.

scientific article published on April 2002

Proteomic approach reveals novel targets for retinoic acid-mediated therapy of thyroid carcinoma

scientific article published on 9 June 2010

Quantitative Analysis of Thyroid Hormone Metabolites in Cell Culture Samples Using LC-MS/MS.

scientific article published on 28 May 2015

Rapid stimulation of type I 5'-deiodinase in rat pituitaries by 3,3',5-triiodo-L-thyronine

scientific article published on 01 February 1995

Re-examination of the subcellular localization of thyroxine 5'-deiodination in rat liver

scientific article

Real time RT-PCR analysis of thyroglobulin mRNA in peripheral blood in patients with congenital athyreosis and with differentiated thyroid carcinoma after stimulation with recombinant human thyrotropin.

scientific article

Redifferentiation therapy of differentiated thyroid carcinoma with retinoic acid: basics and first clinical results

scientific article published on 01 January 1996

Reduced serum selenoprotein P concentrations in German prostate cancer patients.

scientific article published on 18 August 2009

Regulation of CD97 protein in thyroid carcinoma

scientific article published on March 1999

Relaxin-2 connecting peptide (pro-RLX2) levels in second trimester serum samples to predict preeclampsia

scientific article published on 7 November 2017

Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals-The ATHENA Project

scientific article published on 28 April 2020

Report on the 4th International FESTEM Symposium on "Recent advances in trace element research: From experiments to nutritional and clinical applications in humans" (Saint Petersburg, Russia, June 09-12th, 2010).

scientific article published on 15 October 2010

Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system

scientific article published on 22 December 2017

Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells

scientific article published on November 1997

Retinoic acid redifferentiation therapy for thyroid cancer.

scientific article published in May 2000

Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines

scientific article

Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines

scientific article

Reverse transcriptase-polymerase chain reaction analysis of thyrocyte-relevant genes in fine-needle aspiration biopsies of the human thyroid

scientific article published on 01 November 1998

Schilddrüsenhormone – Zentrale Regulatoren von Entwicklung, Wachstum, Grundumsatz, Stoffwechsel und Zelldifferenzierung

Sclerostin Blockade and Zoledronic Acid Improve Bone Mass and Strength in Male Mice With Exogenous Hyperthyroidism

scientific article published on 11 July 2017

Se- and s-based thiouracil and methimazole analogues exert different inhibitory mechanisms on type 1 and type 2 deiodinases

scientific article

Secretion of Antioxidant Peroxiredoxin 4 in Response to Oxidative Stress

Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I

scientific article published on 01 January 1996

Selective affinity labeling of a 27-kDa integral membrane protein in rat liver and kidney with N-bromoacetyl derivatives of L-thyroxine and 3,5,3'-triiodo-L-thyronine

scientific article published on 01 April 1990

Selective labelling and inactivation of creatine kinase isoenzymes by the thyroid hormone derivative N-bromoacetyl-3,3',5-tri-iodo-L-thyronine

scientific article published on April 1993

Selenite supplementation in euthyroid subjects with thyroid peroxidase antibodies

scientific article published on 31 July 2013

Selenium Transport in Mammals: Selenoprotein P and Its Receptors

Selenium and brain function: a poorly recognized liaison

article

Selenium and goiter prevalence in borderline iodine sufficiency

scientific article published in December 2006

Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic

scientific article published in August 2004

Selenium and the control of thyroid hormone metabolism.

scientific article

Selenium and the thyroid

scientific article published on October 2013

Selenium and the thyroid

scientific article published on October 2015

Selenium and thyroid

scientific article published on December 2009

Selenium in endocrinology. Foreword.

scientific article

Selenium status in patients with autoimmune and non-autoimmune thyroid diseases from four European countries

scientific article published on 18 September 2014

Selenium status, thyroid volume, and multiple nodule formation in an area with mild iodine deficiency

scientific article published on 17 January 2011

Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and present carriers of colon adenomas

scientific article published on January 2003

Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.

scientific article

Selenium supply regulates thyroid function, thyroid hormone synthesis and metabolism by altering the expression of the selenoenzymes Type I 5'-deiodinase and glutathione peroxidase

scientific article published on April 1, 1992

Selenium, the thyroid, and the endocrine system.

scientific article

Selenium-dependent pre- and posttranscriptional mechanisms are responsible for sexual dimorphic expression of selenoproteins in murine tissues

scientific article published on 7 September 2006

Selenium-dependent regulation of type I 5'-deiodinase expression

scientific article published on February 1993

Selenoprotein Gene Nomenclature

scientific article published on 19 September 2016

Selenoprotein P and Selenium Distribution in Mammals

Selenoprotein expression in Hürthle cell carcinomas and in the human Hürthle cell carcinoma line XTC.UC1.

scientific article published on May 2005

Selenoproteins - biochemistry and clinical relevance

scientific article published on 01 October 2007

Selenoproteins are expressed in fetal human osteoblast-like cells

scientific article published on April 1998

Selenoproteins of the thyroid gland: expression, localization and possible function of glutathione peroxidase 3.

scientific article

Serum 25-Hydroxyvitamin D and Cancer Risk in Older Adults: Results from a Large German Prospective Cohort Study

article

Serum Thyrotropin Concentrations Are Not Associated with the Ankle-Brachial Index: Results from Three Population-Based Studies

scientific article

Serum selenium is low in newly diagnosed Graves' disease: a population-based study

scientific article published on 27 March 2013

Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P.

scientific article published on 29 December 2016

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in aged mice

scientific article published on 22 December 2017

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice.

scientific article published on 24 August 2016

Silychristin, a Flavonolignan Derived From the Milk Thistle, Is a Potent Inhibitor of the Thyroid Hormone Transporter MCT8.

scientific article

Soy isoflavones interfere with thyroid hormone homeostasis in orchidectomized middle-aged rats.

scientific article published on 29 April 2014

Standardization of misleading immunoassay based 25-hydroxyvitamin D levels with liquid chromatography tandem-mass spectrometry in a large cohort study

scientific article

Steroidhormone – Produkte von Nebennierenrinde und Keimdrüsen

Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study

scientific article

Structural insights into thyroid hormone transport mechanisms of the L-type amino acid transporter 2.

scientific article published on 6 May 2015

Structure of the human type I iodothyronine 5'-deiodinase gene and localization to chromosome 1p32-p33.

scientific article published on June 1997

Subcellular localization of thyroxine-5-deiodinase in rat liver

scientific article published on 01 January 1980

Supplementieren oder nicht? Das Spurenelement Selen

Surface translocation and tri-iodothyronine uptake of mutant MCT8 proteins are cell type-dependent

scientific article

Synthesis and metabolism of thyroid hormones is preferentially maintained in selenium-deficient transgenic mice

scientific article published in December 2005

Synthesis, metabolism and diagnostics of thyroid hormones

scientific article published in May 2010

Synthetic flavonoids cross the placenta in the rat and are found in fetal brain.

scientific article published in February 1998

TRPM8 Activation via 3-Iodothyronamine Blunts VEGF-Induced Transactivation of TRPV1 in Human Uveal Melanoma Cells

scientific article published on 13 November 2018

The Colorful Diversity of Thyroid Hormone Metabolites

scientific article published on 21 May 2019

The Effect of High Dose Isoflavone Supplementation on Serum Reverse T in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women

scientific article published on 22 November 2018

The Multitarget Ligand 3-Iodothyronamine Modulates β-Adrenergic Receptor 2 Signaling ⬇️

scientific article published on 29 May 2015

The Role of Dickkopf-1 in Thyroid Hormone-Induced Changes of Bone Remodeling in Male Mice

scientific article published on 01 March 2019

The human analog of murine cystein rich protein 61 [correction of 16] is a 1alpha,25-dihydroxyvitamin D3 responsive immediate early gene in human fetal osteoblasts: regulation by cytokines, growth factors, and serum

scientific article published in April 1998

The influence of the cytokines Il-1beta and INFgamma on the expression of selenoproteins in the human hepatocarcinoma cell line HepG2.

scientific article

The nude rat is established as a model for endocrine studies: regulation of thyroid function and xenotransplantation of a thyroid tumor cell line

scientific article published on April 1992

The promoter of the human sodium/iodide-symporter gene responds to retinoic acid

scientific article published in March 2002

The promoter of the human type I 5'-deiodinase gene--mapping of the transcription start site and identification of a DR+4 thyroid-hormone-responsive element

scientific article published on July 1997

The selenoenzyme family of deiodinase isozymes controls local thyroid hormone availability.

scientific article

The selenoprotein thioredoxin reductase is expressed in peripheral blood monocytes and THP1 human myeloid leukemia cells--regulation by 1,25-dihydroxyvitamin D3 and selenite

scientific article published on January 1999

The trace components--selenium and flavonoids--affect iodothyronine deiodinases, thyroid hormone transport and TSH regulation.

scientific article published on January 1992

The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase

scientific article published on 22 March 2007

Thyroid Hormones and Derivatives: Endogenous Thyroid Hormones and Their Targets.

scientific article

Thyroid carcinoma: interrelationships between local thyroid hormone metabolism by the type I 5'-deiodinase and the expression of thyroid hormone receptors and other thyroid-specific (de-)differentiation markers.

scientific article published on January 1997

Thyroid function is maintained despite increased oxidative stress in mice lacking selenoprotein biosynthesis in thyroid epithelial cells

scientific article published on 18 April 2012

Thyroid hormone and its metabolites in relation to quality of life in patients treated for differentiated thyroid cancer.

scientific article

Thyroid hormone deiodination in target tissues--a regulatory role for the trace element selenium?

scientific article published on January 1994

Thyroid hormone effect on rat heart mitochondrial proteins and affinity labeling with N-bromoacetyl-3,3',5-triiodo-L-thyronine. Lack of direct effect on the adenine nucleotide translocase

scientific article published on 01 September 1989

Thyroid hormone metabolism and action

scientific article published in May 2004

Thyroid hormone receptors and type I iodothyronine 5'-deiodinase activity of human thyroid toxic adenomas and benign cold nodules

scientific article

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

scientific article published on 12 December 2016

Thyronamine induces TRPM8 channel activation in human conjunctival epithelial cells

scientific article

Thyronamines and Derivatives: Physiological Relevance, Pharmacological Actions, and Future Research Directions

scientific article published on 21 September 2016

Thyronamines are isozyme-specific substrates of deiodinases.

scientific article published on 13 March 2008

Thyronamines--past, present, and future

scientific article

Thyrotropin (TSH) action on thyroid hormone deiodination and secretion: one aspect of thyrotropin regulation of thyroid cell biology.

scientific article published on January 1990

Thyroxine (T4) transport and distribution in rats treated with EMD 21388, a synthetic flavonoid that displaces T4 from transthyretin

scientific article published on March 1992

Thyroxine transport to the brain: role of protein synthesis by the choroid plexus

scientific article published in November 1993

Thyroxine: beneficial for mutated TRα receptors thwarting thyroid hormone action?

scientific article published on 23 June 2014

Topoisomerase I-inhibition enhances vitamin D-responsive expression of the receptor for lipopolysaccharide binding protein CD 14.

scientific article published on March 1994

Trace Amine-Associated Receptor 1 Localization at the Apical Plasma Membrane Domain of Fisher Rat Thyroid Epithelial Cells Is Confined to Cilia

scientific article published on 10 June 2015

Transfer and metabolism of thyroid gland hormones in the placenta

scientific article published on 01 January 1997

Transforming growth factor-beta1 inhibits expression of selenoprotein P in cultured human liver cells

scientific article

Translating pharmacological findings from hypothyroid rodents to euthyroid humans: is there a functional role of endogenous 3,5-T2?

scientific article

Transport of thyroid hormone in brain

scientific article

Type 1 deiodinase is stimulated by iodothyronines and involved in thyroid hormone metabolism in human somatomammotroph GX cells

scientific article published on April 1999

Tyrosine kinase inhibitors noncompetitively inhibit MCT8-mediated iodothyronine transport

scientific article published on 26 October 2011

Urine Metabolomics by (1)H-NMR Spectroscopy Indicates Associations between Serum 3,5-T2 Concentrations and Intermediary Metabolism in Euthyroid Humans

scientific article

V2 vasopressin receptor deficiency causes changes in expression and function of renal and hypothalamic components involved in electrolyte and water homeostasis

scientific article published on 20 August 2008

Vascular Endothelial Growth Factor (VEGF) Induced Downstream Responses to Transient Receptor Potential Vanilloid 1 (TRPV1) and 3-Iodothyronamine (3-TAM) in Human Corneal Keratocytes

article

Wachstumshormon und Prolactin

article

Welcome to thyroid research

scientific article published on 29 September 2008

Xanthohumol stimulates iodide uptake in rat thyroid-derived FRTL-5 cells

scientific article published on September 2005

Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism

scientific article published on July 2010

[Expression of selenoproteins in monocytes and macrophages--implications for the immune system]

scientific article published on 01 October 1999

[How does iodine reach the thyroid gland? Recent studies of the sodium-iodide symporter]

scientific article published on 01 June 1998

[Selenoproteins in bone, gastrointestinal tract and thyroid gland of the human]

scientific article published on 01 September 1997

[The sodium-iodide-symporter (NIS): function, regulation and clinical importance]

scientific article published on 01 April 1999

pH-dependency of iodothyronine metabolism in isolated perfused rat liver

scientific article

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