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List of works by Stefan Engelhardt

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes

scientific article

A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor

scientific article published on August 2011

A role for caspase-1 in heart failure

scientific article published on 15 February 2007

A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart

scientific journal article

Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology

scientific article published in 2014

Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6.

scientific article

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

scientific article published on 27 April 2020

Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice

scientific article published in April 2003

Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation

scientific article published on 16 February 2004

Alternative signaling: cardiomyocyte beta1-adrenergic receptors signal through EGFRs

scientific article published on September 2007

Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: progressive reduction of beta 1-adrenergic receptor mRNA in heart failure

scientific article published on 01 January 1996

Analysis of receptor oligomerization by FRAP microscopy.

scientific article

Beta-adrenergic receptors in heart failure.

scientific article published on July 2005

Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination

scientific article published on 18 October 2016

Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice

scientific article published on 9 April 2004

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

scientific article

Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling

scientific article published on 20 November 2017

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

scientific article

Characterization of circular RNAs in human, mouse and rat hearts

scientific article

Circadian and short-term regulation of blood pressure and heart rate in transgenic mice with cardiac overexpression of the beta1-adrenoceptor

scientific article

Circular RNAs in heart failure

scientific article published on 27 March 2017

Coinciding functions for miR-145 in vascular smooth muscle and cardiac fibroblasts

scientific article published on 17 October 2013

Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy

scientific article published on 17 November 2003

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

scientific article published on February 2011

Critical Role for Stromal Interaction Molecule 1 in Cardiac Hypertrophy ⬇️

scientific article published on August 16, 2011

Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction.

scientific article

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

scientific article published on 12 October 2006

Development of an intein-mediated split-Cas9 system for gene therapy

scientific article

Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion

scientific article published on 24 March 2011

Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production.

scientific article published in September 2013

Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis

scientific article

Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling

scientific article

FHL2 expression and variants in hypertrophic cardiomyopathy

scientific article

G proteins: more than transducers of receptor-generated signals?

scientific article

GPCR and G proteins: drug efficacy and activation in live cells.

scientific article

Gs activation is time-limiting in initiating receptor-mediated signaling.

scientific article published on 8 September 2006

Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling

scientific article published on 22 November 2017

Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen

scientific article published on 18 February 2014

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice

scientific article published on 01 April 2002

Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy

scientific article published on 24 August 2006

Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor

scientific article published on 19 April 2007

Intercellular miRNA Traffic

scientific article published on 01 May 2015

Interhelical interaction and receptor phosphorylation regulate the activation kinetics of different human β1-adrenoceptor variants.

scientific article published on December 2014

Internet discussion forums as part of a student-centred teaching concept of pharmacology

scientific article

Interstitial remodeling in beta1-adrenergic receptor transgenic mice

scientific article published on 24 November 2006

Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice

scientific article

Long noncoding RNA Chast promotes cardiac remodeling

scientific article

MiR-223 is dispensable for platelet production and function in mice

scientific article published on 26 September 2013

MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors

scientific article

MicroRNA Augmentation of Bone Marrow-Derived Cell Therapy

scientific article published on 01 November 2015

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

scientific journal article

MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia.

scientific article published on 8 July 2015

MicroRNA-24 regulates vascularity after myocardial infarction

scientific article published on 25 July 2011

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure

scientific article (publication date: 17 July 2007)

OnlineTED.com--a novel web-based audience response system for higher education. A pilot study to evaluate user acceptance

scientific article

Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

scientific article published on 11 September 2020

Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?

scientific article published on 5 November 2008

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

scientific article published on 7 July 2003

Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium

scientific article published on 15 August 2016

Pharmacases.de - a student-centered e-learning project of clinical pharmacology.

scientific article

Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease

scientific article

Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy

scientific article published on 09 March 2009

Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation

scientific article published on September 2017

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

scientific article

Proteomics strategies in cardiovascular research.

scientific article published on March 2004

Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice

scientific article published in November 2004

Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase

scientific article published on 31 July 2014

Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis

scientific article published on 22 November 2004

Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol

scientific article

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

scientific article published on 16 November 2011

Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling

scientific article

Small RNA Biomarkers Come of Age ⬇️

scientific article published on July 24, 2012

The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.

scientific article

The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance

scientific article published on 09 May 2013

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

scientific article published on January 2012

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

scientific article published on 17 July 2005

Tocolytic therapy with fenoterol induces selective down-regulation of beta-adrenergic receptors in human myometrium

scientific article published on 01 April 1997

Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment

scientific article

Use of learning media by undergraduate medical students in pharmacology: a prospective cohort study

scientific article

Viral Vector-Based Targeting of miR-21 in Cardiac Nonmyocyte Cells Reduces Pathologic Remodeling of the Heart

scientific article published on 22 August 2016

What is the role of beta-adrenergic signaling in heart failure?

scientific article published on November 2003

microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription.

scientific article

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