List of works by Lindsay A. Farrer

46,XY/47,XYY male with the fragile X syndrome: Cytogenetic and molecular studies

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder

scientific article

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

scientific article

A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women

scientific article published on 13 October 2011

A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains

scientific article published on 18 January 2017

A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia

scientific article published on 7 August 2016

A case of inappropriate apolipoprotein e testing in Alzheimer's disease due to lack of an informed consent discussion

scientific article published on 10 March 2014

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

scientific article published on 19 June 2017

A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia

scientific article

A comprehensive genetic association study of Alzheimer disease in African Americans

scientific article

A contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans

scientific article

A family history study of male sexual orientation using three independent samples.

scientific article

A functional promoter polymorphism of the δ-globin gene is a specific marker of the Arab-Indian haplotype

scientific article published on 28 May 2012

A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study

scientific article published on 9 November 2011

A genomewide linkage scan of cocaine dependence and major depressive episode in two populations

scientific article

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A linkage group of five DNA markers on human chromosome 10

scientific article published on 01 July 1988

A network model to predict the risk of death in sickle cell disease

scientific article

A new human RFLP identified by 7D2 places D13S10 proximal to esterase D

scientific article published on 01 January 1987

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A novel mutation in the MITF gene causes Waardenburg Syndrome Type 2

article

A phased SNP-based classification of sickle cell anemia HBB haplotypes

scientific article published on 11 August 2017

A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke.

scientific article published on 12 April 2016

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

scientific article published on 27 November 2017

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

scientific article

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.

scientific article

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

scientific article

ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure

scientific article

APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis

scientific article

APOE, vascular pathology, and the AD brain

scientific article published in July 2005

Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE.

scientific article published in July 1998

Adolescent cannabis use increases risk for cocaine-induced paranoia

scientific article

Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders

scientific article published on 08 August 2009

Agitated depression in substance dependence

scientific article

Allele ε4 of Apolipoprotein E Shows a Dose Effect on Age at Onset of Pick Disease

scientific article published on 01 December 1995

Alpha-2 macroglobulin gene in early- and late-onset Alzheimer disease.

scientific article published in August 1999

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

scientific article

Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease

scientific article published on May 1998

An alpha satellite DNA polymorphism specific for the centromeric region of chromosome 13.

scientific article published in May 1990

An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.

scientific article published in May 1999

An anthropometric assessment of Huntington's disease patients and families

scientific article published in July 1985

Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease

scientific article published on 02 September 2020

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease

article

Analysis of the glucocerebrosidase gene in Parkinson's disease

article

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations

scientific article published on 05 December 2018

Ancestry of African Americans with sickle cell disease

scientific article

Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world

scientific article published on 9 July 2015

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors

scientific article published on 9 October 2017

Anthropometric discrimination among affected, at-risk, and not-at-risk individuals in families with Huntington disease

scientific article published in June 1985

Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease

scientific article published in September 1997

Apolipoprotein E genotype in patients with alzheimer's disease: Implications for the risk of dementia among relatives

article

Assessment of genetic risk for Alzheimer's disease among first-degree relatives

scientific article

Assessment of the genetic variance of late-onset Alzheimer's disease

scientific article published on 03 March 2016

Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus

scientific article published on March 1985

Association Between Angiotensin-Converting Enzyme and Alzheimer Disease

scientific article published on 01 February 2000

Association between SORL1 and Alzheimer's disease in a genome-wide study

scientific article

Association between apolipoprotein E genotype and Alzheimer disease in African American subjects

scientific article published in April 2002

Association between bleomycin hydrolase and Alzheimer's disease in caucasians

scientific article published in November 1998

Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations

scientific article published on 08 June 2011

Association of COL25A1 with comorbid antisocial personality disorder and substance dependence

scientific article published on 31 January 2012

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

scientific article

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

scientific article

Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families

scientific article

Association of asthma with a functional promoter polymorphism in the IL16 gene

scientific article published on January 2006

Association of decreased paternal age and late-onset Alzheimer's disease. An example of genetic imprinting?

scientific article published in June 1991

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease

scientific article published on December 2008

Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis

scientific article published on September 2013

Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis

scientific article published on 22 March 2005

Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity

scientific article published on 16 December 2016

Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community

scientific article

Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia

scientific article

Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals

scientific article published on 04 September 2008

Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia

scientific article published on January 2005

Association of variants in MANEA with cocaine-related behaviors

scientific article published on March 2009

Association studies between the plasmin genes and late-onset Alzheimer's disease

scientific article

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q.

scientific article published in November 1998

Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances

scientific article published on 21 February 2012

BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.

scientific article

BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies

scientific article published on 8 August 2008

Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide repeat

scientific article published in 2012

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

scientific article

Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants

scientific article published on 6 October 2017

Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue

scientific article published on 27 April 2021

Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males

scientific article published on 19 October 2011

Clinical anthropometry and medical genetics: a compilation of body measurements in genetic and congenital disorders

scientific article

Collection of clinical and epidemiological data for genetic linkage and association studies.

scientific article

Collection of clinical and epidemiological data for linkage studies

scientific article

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects

scientific article published in September 2007

Comparison of Alzheimer's disease risk factors in white and African American families

scientific article published in April 2003

Complement factor H polymorphism and age-related macular degeneration

scientific article (publication date: 15 April 2005)

Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

scientific article published on October 2012

Confirmation and generalization of an alcohol-dependence locus on chromosome 10q.

scientific article

Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach

scientific article

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

scientific article published on 8 July 2013

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders

scientific article published on 13 May 2008

Correlation between Waardenburg syndrome phenotype and genotype in a population of individuals with identified PAX3 mutations

scientific article published in May 1998

Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.

scientific article

Data compatibility in the addiction sciences: an examination of measure commonality

scientific article

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

scientific article

Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.

scientific article published on 18 October 2008

Depression as a risk factor for Alzheimer disease: the MIRAGE Study

scientific article published in May 2003

Detecting linkage for a complex disease using simulated extended pedigrees

scientific article published in January 1997

Detecting linkage for a complex disease using simulated extended pedigrees

scientific article published in 1997

Development of a map of chromosome 11p

article

Development of a map of chromosome 11p

scientific article published on 01 January 1986

Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study

scientific article published in November 2006

Diabetes mellitus in Huntington disease

scientific article published in January 1985

Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA).

scientific article published in December 2005

Differences between African Americans and Whites in their attitudes toward genetic testing for Alzheimer's disease

scientific article published on January 2003

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

scientific article

Disclosure of APOE genotype for risk of Alzheimer's disease

scientific article published on July 2009

Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium

scientific article

Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition.

scientific article

Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport

scientific article

Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study

scientific article

Education effects on cognitive function in a healthy aged Arab population

scientific article published on 20 October 2006

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Empirically derived phenotypic subgroups - qualitative and quantitative trait analyses

scientific article

Empirically derived subtypes of opioid use and related behaviors

scientific article

Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain

scientific article published on 23 May 2016

Erratum: Genetic risk prediction and neurobiological understanding of alcoholism

scholarly article published in Translational Psychiatry

Essential tremor might be less frequent than Parkinson's disease in North Israel Arab villages

scientific article published on January 2009

Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B

article

Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study

scientific article published in July 2004

Estimating the risk for conversion from mild cognitive impairment to Alzheimer's disease in an elderly Arab community

scientific article published in January 2015

Estimation of familial risk in Alzheimer's disease

scholarly article by John C. S. Breitner et al published March 1990 in Annals of Neurology

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

scientific article

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

scientific article

Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity

scientific article published in August 1998

Evidence for linkage between Wilson disease and esterase D in three kindreds: detection of linkage for an autosomal recessive disorder by the family study method

scientific article published in January 1986

Evidence for linkage between essential hypertension and a putative locus on human chromosome 17.

scientific article

Evidence of CNIH3 involvement in opioid dependence.

scientific article published on 4 August 2015

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

scientific article published on 03 November 2020

Expanding the genomic roadmap of Alzheimer's disease

scientific article published on 30 June 2015

Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks

scientific article published on 02 October 2021

Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants

scientific article published on 03 December 2013

Eye color: A potential indicator of alcohol dependence risk in European Americans

scientific article published on 29 April 2015

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease

scientific article

FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression

scientific article

Familial Alzheimer's disease: progress and problems

scientific article published on September 1989

Familial risk for Alzheimer disease in ethnic minorities: nondiscriminating genes.

scientific article published in January 2000

Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea

article

Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype

scientific article

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

scientific article

Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene

scientific article

Further analyses support the association between light eye color and alcohol dependence

Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease

scientific article published on 14 March 2008

GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans

scientific article published on 15 September 2011

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

scientific article

Gender equality in Machado–Joseph disease

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic Relationship between Schizophrenia and Nicotine Dependence

scientific article published on 10 May 2016

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

scientific article published on 25 October 2017

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.

scientific article published on 27 February 2018

Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

scientific article (publication date: June 2014)

Genetic and environmental epidemiology of Alzheimer's disease in arabs residing in Israel

scientific article

Genetic and environmental risk factors for Alzheimer's disease in Israeli Arabs

scientific article

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

scientific article

Genetic association between endothelial nitric oxide synthase and Alzheimer disease

scientific article published in July 2006

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

scientific article

Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions

scientific article

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.

scientific article published in September 1990

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study

scientific article

Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus

scientific article

Genetic predisposition to stroke in relatives of hypertensives.

scientific article published in February 2000

Genetic risk prediction and neurobiological understanding of alcoholism

scientific article

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

scientific article published on 01 August 2020

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

scientific article (2010)

Genetic variants of WNK4 in whites and African Americans with hypertension

scientific article

Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes

scientific article

Genetics of age-related macular degeneration (AMD).

scientific article published in October 2017

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.

scientific article published on 4 October 2017

Genome-Wide Association Study of Opioid Cessation

scientific article published on 09 January 2020

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes

scientific article published on 11 July 2019

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

scientific article published on 11 January 2018

Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks

scientific article published on 30 March 2016

Genome-wide analysis of genetic loci associated with Alzheimer disease

scientific article

Genome-wide association meta-analysis of age at first cannabis use

scientific article published on 19 August 2018

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

scientific article

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

scientific article published on 3 October 2017

Genome-wide association study identifies a novel locus for cannabis dependence

scientific article published on 7 November 2017

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

scientific article published on 28 February 2017

Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder

scientific journal article

Genome-wide association study of Alzheimer's disease

scientific article

Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.

scientific article published on 20 December 2017

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

scientific article

Genome-wide association study of body mass index in subjects with alcohol dependence

scientific article published on 12 October 2015

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene

scientific article published on 20 August 2013

Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test

scientific article published on 01 July 2018

Genome-wide association study of copy number variations (CNVs) with opioid dependence

scientific article

Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.

scientific article

Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways

scientific article published on 19 October 2013

Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

scientific article published on 23 June 2020

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

scientific article

Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.

scientific article published on 24 January 2017

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

scientific article

Genome-wide linkage analysis for alcohol dependence: a comparison between single-nucleotide polymorphism and microsatellite marker assays

scientific article

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

scientific article published on 06 October 2015

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease

scientific article published on 20 February 2018

Genome-wide screen for heavy alcohol consumption

scientific article

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans

scientific article

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

scientific article published on 22 February 2017

Genomewide Linkage Scan for Nicotine Dependence: Identification of a Chromosome 5 Risk Locus

Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia

scientific article published in July 2005

Genomewide linkage scan for opioid dependence and related traits

scientific article

Genomic influences on self-reported childhood maltreatment

scientific article published on 27 January 2020

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

scientific article

Glucuronic acid epimerase is associated with plasma triglyceride and high-density lipoprotein cholesterol levels in Turks

scientific article published on May 2011

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.

scientific article published on 3 November 2006

Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease.

scientific article

Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project.

scientific article published in November 2010

Hemolysis-associated priapism in sickle cell disease

scientific article published on 28 June 2005

Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study

scientific article

High prevalence of mild cognitive impairment and Alzheimer's disease in arabic villages in northern Israel: impact of gender and education

scientific article published on January 2012

Highly Polymorphic Short Tandem Repeat Analyses Clarify Complex Molecular Test Results

scientific article published on 01 September 2001

Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia

scientific article published on 28 April 2016

Human induced pluripotent stem cells illuminate pathways and novel treatment targets for age-related macular degeneration

scientific article published on 17 November 2017

Hypertension increases the probability of Alzheimer's disease and of mild cognitive impairment in an Arab community in northern Israel.

scientific article

Identification of Alzheimer disease-associated variants in genes that regulate retromer function

scientific article

Identification of a polymorphic glutamic acid stretch in the α2b-adrenergic receptor and lack of linkage with essential hypertension

scientific article published on 01 September 1999

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

scientific article published on 15 September 2013

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

scientific article published on July 2013

Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community.

scientific article published in February 2003

Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data

scientific article

Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes.

scientific article

Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors

scientific article

Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience

scientific article published on March 2008

Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)

scientific article published on 14 May 2013

Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology

scientific article

Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci

scientific article published on 30 January 2013

Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence

scientific article

Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease

scientific article published on 03 September 2021

Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample

scientific article

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder

scientific article

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations

scientific article

Intercontinental Epidemiology of Alzheimer Disease

scientific article published in The Journal of the American Medical Association

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Interrater agreement for diagnosis of Alzheimer's disease: the MIRAGE study.

scientific article published in April 1994

Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans

scientific article

Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, Israel

scientific article published on March 2005

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

scientific article published on 25 April 2017

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

scientific article published on 26 February 2020

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

scientific article

Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans

scientific article published on 19 April 2012

Linkage analysis of multiple endocrine neoplasia type 2A (MEN-2A) and three DNA markers on chromosome 20: Evidence against synteny

scientific article published on 01 August 1987

Linkage disequilibrium analysis in Machado-Joseph disease patients of different ethnic origins

article

Linkage of late-onset Alzheimer's disease with apolipoprotein E type 4 on chromosome 19.

scientific article published in September 1993

Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35

scientific article

Machado Joseph disease is not an allele of the spinocerebellar ataxia 2 locus

scientific article published on March 1994

Machado Joseph disease maps to the same region of chromosome 14 as the spinocerebellar ataxia type 3 locus

scientific article

Magnetic resonance imaging traits in siblings discordant for Alzheimer disease

scientific article published on July 2008

Magnetic resonance imaging-measured atrophy and its relationship to cognitive functioning in vascular dementia and Alzheimer's disease patients

scientific article

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

article

Managing data for genetic linkage analysis

scientific article published in July 1986

Maternal component in the familial aggregation of hypertension

scientific article published on 01 July 2001

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

scientific article

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

scientific article published on 29 March 2016

Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Meta-analysis of the association between variants in SORL1 and Alzheimer disease

scientific article

Mild cognitive impairment is associated with mild parkinsonian signs in a door-to-door study.

scientific article published on January 2010

Missense variant in TREML2 protects against Alzheimer's disease

scientific article published on 21 December 2013

Molecular genetics of familial Alzheimer's disease

scientific article

Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs.

scientific article published in November 1992

Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies

scientific article

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

scientific article published in August 2005

Multiple loci influencing hippocampal degeneration identified by genome scan

scientific article

Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain

scientific article published on 26 April 2016

Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans

scientific article published on 19 August 2014

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

scientific article

No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples.

scientific article

No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.

scientific article published in December 1996

No association between the HLA-A2 allele and Alzheimer disease.

scientific article published on September 1999

No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease

scientific article published in 1997

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.

scientific article published in March 1998

No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.

scientific article published in April 1996

Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study

scientific article

Novel ATP7B mutations causing Wilson disease in several Israeli ethnic groups

scientific article published in 1998

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

scientific article published on 19 October 2020

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

One for all and all for One: Improving replication of genetic studies through network diffusion.

scientific article published on 23 April 2018

One large kindred excludes a locus for multiple endocrine neoplasia type 2A from about 25% of the human autosomal genetic map.

scientific article published on January 1987

Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study

scientific article published on 08 July 2017

PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

scientific article published on 29 July 2014

Performance of random forest when SNPs are in linkage disequilibrium.

scientific article

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

scientific article

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

scientific article

Polymorphisms in the PON gene cluster are associated with Alzheimer disease

scientific article published on 30 November 2005

Polymorphisms in the promoter region of catalase gene and essential hypertension

scientific article published on January 2005

Polymorphisms near a chromosome 6q QTL area are associated with modulation of fetal hemoglobin levels in sickle cell anemia

scientific article published in February 2004

Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future

scientific article published on 23 April 2007

Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease.

scientific article

Prayer at midlife is associated with reduced risk of cognitive decline in Arabic women

scientific article published on March 2013

Predictability of phenotype in Huntington's disease

scientific article published in January 1987

Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease

Predictive testing for Huntington's disease with use of a linked DNA marker

scientific article published in March 1988

Predictive testing for Wilson's disease using tightly linked and flanking DNA markers

scientific article published on 01 July 1991

Predictors of subjective memory complaint in cognitively normal relatives of patients with Alzheimer's disease

scientific article published in January 2006

Presenilin polymorphisms in Alzheimer's disease.

scientific article

Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample

scientific article published on 09 August 2012

Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies

scientific article

Protective variant for hippocampal atrophy identified by whole exome sequencing

scientific article

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Rate of progression of Alzheimer's disease is associated with genetic risk

scientific article

Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).

scientific article published in October 2005

Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease

scientific article

Regulatory region variability in the human presenilin-2 (PSEN2) gene: potential contribution to the gene activity and risk for AD.

scientific article

Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).

scientific article published in January 2005

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA).

scientific article

Reliability of information collected by proxy in family studies of Alzheimer's disease.

scientific article published in May 2001

Reliability of self-reported age at onset of major depression

scientific article published on January 1989

Reply

Reply: To PMID 25559091.

scientific article published on 18 August 2015

Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs

scientific article published on 18 January 2006

Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?

scientific article published in March 1996

Risk of dementia among white and African American relatives of patients with Alzheimer disease.

scientific article published in January 2002

Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts

scientific article published on 15 February 2013

S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours

scientific article

SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

scientific article

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

scientific article

Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways

scientific article published on 19 December 2013

Search for genetic factors predisposing to atherogenic dyslipidemia

scientific article

Segregation analysis of total nevus density and estimation of lifetime risk and average onset age of melanoma ⬇️

scientific article published on January 1, 1992

Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease

scientific article published on 14 January 2016

Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study

scientific article

Serum heat shock protein 70 level as a biomarker of exceptional longevity

scientific article published on 6 October 2006

Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease

scientific article

Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants

scientific article published in 2021

Seven new loci associated with age-related macular degeneration

scientific article

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway

scientific article

Smoking and risk of Alzheimer's disease. MIRAGE Study Group.

scientific article published in September 1998

Statement on Use of Apolipoprotein E Testing for Alzheimer Disease

scientific article published in The Journal of the American Medical Association

Statin use and the risk of Alzheimer's disease: the MIRAGE study

scientific article published in April 2006

Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes

scientific article

Substance dependence low-density whole genome association study in two distinct American populations

scientific article

Subtypes of major depression in substance dependence.

scientific article

Suicide and attempted suicide in Huntington disease: implications for preclinical testing of persons at risk

scientific article published in June 1986

Susceptibility genes for familial Alzheimer's disease on chromosomes 19 and 21: a reality check.

scientific article published in January 1993

Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration

scientific article

Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans.

scientific article published on 7 March 2018

The Alzheimer's Disease Sequencing Project: Study design and sample selection

scientific article published on 13 October 2017

The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene

scientific article published on 17 August 2016

The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1)

scientific article published on 01 July 1992

The Nevada Vital Aging Initiative: A private-public partnership to study early predictors of dementia

scientific article published on 01 January 2007

The PhenX Toolkit: get the most from your measures

scientific article

The angiotensin-converting enzyme gene as a possible risk or protective factor in Alzheimer's disease.

scientific article published in March 2001

The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort

scientific article published on April 2007

The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective

scientific article published on March 1997

The genetics of adult-onset neuropsychiatric disease: complexities and conundra?

scientific article

The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14

scientific article published on March 1, 1992

The natural history of Huntington disease: possible role of "aging genes".

scientific article

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

scientific article

The serotonin receptor subtype 2 locus HTR2 is on human chromosome 13 near genes for esterase D and retinoblastoma-1 and on mouse chromosome 14.

scientific article

The ticking clock of Cayo Santiago macaques and its implications for understanding human circadian rhythm disorders

scientific article

The validity of cocaine dependence subtypes

scientific article

The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder

scientific article published on 28 January 2014

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scholarly article published 10 March 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

scientific article published on 6 February 2017

Transient Cocaine-Associated Behavioral Symptoms Rated with a New Instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP)

article

Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP).

scientific article

Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity.

scientific article published in March 1990

Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans

scientific article published on 19 October 2016

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

scientific article

Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong.

scientific article published in June 2008

Variation in OPRM1 and risk of suicidal behavior in drug-dependent individuals

scientific article published on 15 December 2011

Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

scientific article

Variations in opioid receptor genes in neonatal abstinence syndrome

scientific article published on 8 July 2015

Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

scientific article

Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial

scientific article published in July 2004

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.

scientific article published on 13 March 2018

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

scientific article published on 23 April 2013

Whole-genome variance components linkage analysis using single-nucleotide polymorphisms versus microsatellites on quantitative traits of derived phenotypes from factor analysis of electroencephalogram waves

scientific article

β-Globin gene cluster polymorphisms are strongly associated with severity of HbE/β0-thalassemia

article

δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes

scientific article

Paulina is supported by:

About Paulina

Help