List of works - Catherine Day

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

scientific article published in Nature Communications

A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers

scientific article published on 17 August 2020

A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome

scientific article

Assembling the building blocks: structure and function of inhibitor of apoptosis proteins

scientific article published on January 2010

Asymmetric recruitment of cIAPs by TRAF2

scientific article

Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices

scientific article published in November 2009

Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets

scientific journal article

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

scientific article published on 15 April 2014

CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

scientific article

Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

scientific article

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

scientific article

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

scientific article published in June 2001

E2 enzymes: lessons in ubiquitin transfer from XLID patients

scientific article published on 10 December 2018

Enhancing the peroxidase activity of cytochromecby mutation of residue 41: implications for the peroxidase mechanism and cytochromecrelease

scientific article published on 01 March 2014

Expression and characterisation of the n-terminal half of human lactoferrin

1993 doctoral thesis by Catherine Louise Day at Massey University

FCA does not bind abscisic acid

scientific article

FRIGIDA and related proteins have a conserved central domain and family specific N- and C- terminal regions that are functionally important

scientific article published on 20 April 2010

HtrA--a renaissance protein

scientific article

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

scientific article

IAPs: Modular regulators of cell signalling

scientific article published on 24 December 2014

Intrinsically disordered proteins in bcl-2 regulated apoptosis.

scientific article

Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants

scientific article

Preliminary crystallographic studies of the amino terminal half of human lactoferrin in its iron-saturated and iron-free forms

scientific article published on 01 December 1992

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

scientific article

RING domain dimerization is essential for RNF4 function

scientific article

RINGs hold the key to ubiquitin transfer

scientific article published on 10 December 2011

Reevaluation of abscisic acid-binding assays shows that G-Protein-Coupled Receptor2 does not bind abscisic Acid

scientific article published on 13 March 2009

Regulation of apoptosis: uncovering the binding determinants

scientific article

Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase

scientific article

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

scientific article

Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization

scientific article published on 10 March 2011

Solution structure of Psb27 from cyanobacterial photosystem II

scientific article

Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

scientific article

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

scientific article

Structural insights into the degradation of Mcl-1 induced by BH3 domains

scientific article

Structural plasticity underpins promiscuous binding of the prosurvival protein A1

scientific article

Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B

scientific article

Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1

scientific article

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

scientific article

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

scientific article

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

scientific article

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

scientific article published on December 2009

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

scientific article published on November 2006

The Bcl-2-regulated apoptotic pathway

scientific article

The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly

scientific article published on 17 July 2013

The RING domain of RING Finger 11 (RNF11) protein binds Ubc13 and inhibits formation of polyubiquitin chains

scientific article published on 14 March 2018

The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.

scientific article

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

scientific article

The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.

scientific article published on 23 November 2015

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

scientific article

The structure of Boo/Diva reveals a divergent Bcl-2 protein

scientific article

The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation

scientific article

Tissue distribution of Diablo/Smac revealed by monoclonal antibodies.

scientific article

Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.

scientific article

Use of E2~ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins

scientific article

List of works by Catherine Day

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

A cryptic tubulin-binding domain links MEKK1 to curved tubulin protomers

A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome

Assembling the building blocks: structure and function of inhibitor of apoptosis proteins

Asymmetric recruitment of cIAPs by TRAF2

Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices

Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

E2 enzymes: lessons in ubiquitin transfer from XLID patients

Enhancing the peroxidase activity of cytochromecby mutation of residue 41: implications for the peroxidase mechanism and cytochromecrelease

Expression and characterisation of the n-terminal half of human lactoferrin

FCA does not bind abscisic acid

FRIGIDA and related proteins have a conserved central domain and family specific N- and C- terminal regions that are functionally important

HtrA--a renaissance protein

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

IAPs: Modular regulators of cell signalling

Intrinsically disordered proteins in bcl-2 regulated apoptosis.

Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants

Preliminary crystallographic studies of the amino terminal half of human lactoferrin in its iron-saturated and iron-free forms

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

RING domain dimerization is essential for RNF4 function

RINGs hold the key to ubiquitin transfer

Reevaluation of abscisic acid-binding assays shows that G-Protein-Coupled Receptor2 does not bind abscisic Acid

Regulation of apoptosis: uncovering the binding determinants

Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase

Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity

Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization

Solution structure of Psb27 from cyanobacterial photosystem II

Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

Structural insights into the degradation of Mcl-1 induced by BH3 domains

Structural plasticity underpins promiscuous binding of the prosurvival protein A1

Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B

Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

The Bcl-2-regulated apoptotic pathway

The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly

The RING domain of RING Finger 11 (RNF11) protein binds Ubc13 and inhibits formation of polyubiquitin chains

The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

The structure of Boo/Diva reveals a divergent Bcl-2 protein

The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylation

Tissue distribution of Diablo/Smac revealed by monoclonal antibodies.

Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.

Use of E2~ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins