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List of works by Vasili Hauryliuk

A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

scientific article published on 11 May 2020

A widespread toxin-antitoxin system exploiting growth control via alarmone signaling

scientific article published on 28 April 2020

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

scientific article published on 28 December 2018

Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis.

scientific article

An ancient family of SelB elongation factor-like proteins with a broad but disjunct distribution across archaea ⬇️

scientific article published on January 21, 2011

An evolutionary ratchet leading to loss of elongation factors in eukaryotes

scientific article

Analysis of nucleotide pools in bacteria using HPLC-MS in HILIC mode

scientific article published on 18 July 2019

Antibacterial activity of the nitrovinylfuran G1 (Furvina) and its conversion products.

scientific article

Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

scientific article published on 5 February 2018

Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

scientific article

Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp

scientific article

Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

scientific article published in 2024

Class-1 release factor eRF1 promotes GTP binding by class-2 release factor eRF3

scientific article

Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli.

scientific article published on 29 February 2016

Does the ribosome have initiation and elongation modes of translation?

scientific article published on 25 May 2009

Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes

scientific article

Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components

scientific article

Evolution of translational machinery: could translation termination come into being before elongation?

scientific article published on 09 June 2007

Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae

scientific article

From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis

scientific article

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding

scientific article published on 11 November 2009

GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner

scientific article

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

scientific article

HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp

scientific article published on 8 September 2017

In Vitro Studies of Persister Cells

scientific article published on 11 November 2020

Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

scientific article published on 27 August 2019

Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)

scientific article

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

scientific article

Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.

scientific article

Persisters-as elusive as ever

scientific article

Positive allosteric feedback regulation of the stringent response enzyme RelA by its product

scientific article published on 20 July 2012

Protein biosynthesis in mitochondria

scientific article published on August 2013

Reanalysis of Proteomics Results Fails To Detect MazF-Mediated Stress Proteins

scientific article published on 11 June 2019

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells.

scientific article published on 12 June 2018

Recent functional insights into the role of (p)ppGpp in bacterial physiology

scientific article

Reply to Holden and Errington, "Type II Toxin-Antitoxin Systems and Persister Cells"

scientific article published on 25 September 2018

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

scientific article published on 28 February 2019

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

scientific article published on 01 August 2021

Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40 ⬇️

scientific article published on December 14, 2011

Single-molecule investigations of the stringent response machinery in living bacterial cells

scientific article

Small Alarmone Synthetases as novel bacterial RNA-binding proteins.

scientific article published on 18 August 2017

Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G.

scientific article

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

scientific article published on 19 November 2020

Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.

scientific article published on 11 January 2018

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics

scientific article published on 6 April 2022

Structural basis for antibiotic resistance mediated by the ABCF ATPase VmlR

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

scientific article published on 11 June 2021

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.

scientific article published on 23 January 2017

The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis

scientific article published on 02 August 2019

The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life

scientific article published in 2011

The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

scientific article

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

scholarly article

The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.

scientific article published on 30 January 2018

The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis

scientific article

Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp

scientific article

Thermodynamics of GTP and GDP binding to bacterial initiation factor 2 suggests two types of structural transitions.

scientific article published on 22 October 2009

Two-step selection of mRNAs in initiation of protein synthesis

scientific article published in April 2006

Uncovering new families and folds in the natural protein universe

scientific article published on 13 September 2023

What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds

[GTPases of prokaryotic translational apparatus]

scientific article published on 01 September 2006

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