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List of works by Cahir J O'Kane

A phagocytic route for uptake of double-stranded RNA in RNAi

scientific article

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

scientific article

A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila.

scientific article

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

scientific article published on 21 June 2010

Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies

scientific article published in December 1996

Automated measurement of Drosophila jump reflex habituation and its use for mutant screening

scientific article published on 9 June 2009

Characterization of the Drosophila atlastin interactome reveals VCP as a functionally related interactor.

scientific article published on 9 May 2013

Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights

scientific article

Complex inhibitory effects of nitric oxide on autophagy

scientific article

Cullin-3 regulates pattern formation, external sensory organ development and cell survival during Drosophila development

scientific article published in December 2004

Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion

scientific article published on 21 December 2005

Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation.

scientific article published on December 2007

Drosophila as a Model Organism for the Study of Neuropsychiatric Disorders ⬇️

scientific article published on January 1, 2011

Drosophila paramyosin is important for myoblast fusion and essential for myofibril formation.

scientific article

Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules

scientific article

Dynein mutations impair autophagic clearance of aggregate-prone proteins

scientific article

Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development.

scientific article

GAL4 Drivers Specific for Type Ib and Type Is Motor Neurons in Drosophila

scientific article published on 07 February 2019

GAL4 drivers specific for Type Ib and Type Is motor neurons in Drosophila

Genetic feminization of pheromones and its behavioral consequences in Drosophila males.

scientific article

Hereditary spastic paraplegias: membrane traffic and the motor pathway

scientific article published on January 2011

Identification and characterization of the gene for Drosophila L3 ribosomal protein.

scientific article

Identification and characterization of the gene for Drosophila S20 ribosomal protein.

scientific article published on October 1997

Inducible ternary control of transgene expression and cell ablation in Drosophila

scientific article published on 01 June 1996

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

scientific article

Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster.

scientific article published in April 2005

Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway

scientific article published on 2 September 2005

Localized olfactory representation in mushroom bodies of Drosophila larvae.

scientific article

Lysosomal positioning coordinates cellular nutrient responses.

scientific article published on 13 March 2011

Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins.

scientific article published on 25 July 2017

Multiple spectral inputs improve motion discrimination in the Drosophila visual system.

scientific article published in May 2012

Network adaptation improves temporal representation of naturalistic stimuli in Drosophila eye: I dynamics

scientific article

NeuroGeM, a knowledgebase of genetic modifiers in neurodegenerative diseases

scientific article

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

scientific article published on May 2008

Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy ⬇️

scientific article published on September 9, 2010

Rapamycin alleviates toxicity of different aggregate-prone proteins

scientific article published on 20 December 2005

Rapamycin pre-treatment protects against apoptosis

scientific article published on 23 February 2006

Reticulon-like-1, the Drosophila orthologue of the Hereditary Spastic Paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons ⬇️

scientific article published on April 27, 2012

Shaw potassium channel genes inDrosophila

article

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

scientific article

Stereotypic and random patterns of connectivity in the larval mushroom body calyx of Drosophila

scientific article

Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input in Drosophila

scientific article published in February 2002

Targeting expression to projection neurons that innervate specific mushroom body calyx and antennal lobe glomeruli in larval Drosophila.

scientific article

The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster

scientific article

The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila

scientific article

The fascination of the Drosophila NMJ.

scientific article published on March 1997

The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling

scientific article

The nuclear protein Waharan is required for endosomal-lysosomal trafficking in Drosophila

scientific article published on 15 June 2010

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

scientific article

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