List of works - Cathrine B Vågbø

A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation

scientific article

A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.

scientific article published on 7 February 2011

A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported

scientific article published on 3 June 2013

A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.

scientific article published on 8 November 2017

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

scientific article

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

scientific article

AlkB demethylases flip out in different ways

scientific article published on 06 September 2008

Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism

scientific article published on 2 March 2016

Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

scientific article published on 31 May 2016

Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation

scientific article

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage

scientific article

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA

scientific article

Identification of a novel, widespread, and functionally important PCNA-binding motif

scientific article

Insights into the mechanisms of ifosfamide encephalopathy: drug metabolites have agonistic effects on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors and induce cellular acidification in mouse cortical neurons

scientific article published in December 2001

Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding

scientific article

Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.

scientific article published on 29 December 2012

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia

scientific article published on 27 December 2016

Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities

scientific article

RNA base damage and repair

scientific article published on December 2007

Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification

scientific article published on 09 May 2019

Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA

scientific article

Roles of Trm9- and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.

scientific article

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

scientific article published on 16 December 2015

The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage

scientific article

The DNA modification N6-methyl-2'-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction

scientific article published on 18 February 2019

The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control

scientific article

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation

scientific article

Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6

scientific article published on 01 July 1998

m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.

scientific article

List of works by Cathrine B Vågbø

A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation

A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.

A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported

A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA

AlkB demethylases flip out in different ways

Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism

Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells

Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA

Identification of a novel, widespread, and functionally important PCNA-binding motif

Insights into the mechanisms of ifosfamide encephalopathy: drug metabolites have agonistic effects on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors and induce cellular acidification in mouse cortical neurons

Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding

Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia

Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities

RNA base damage and repair

Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification

Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA

Roles of Trm9- and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage

The DNA modification N6-methyl-2'-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction

The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation

Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6

m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.