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List of works by Masaru Okabe

'Green mice' and their potential usage in biological research.

scientific article published in June 1998

'Green mice' as a source of ubiquitous green cells.

scientific article

A codon exchange DAF is a powerful material for xenografting

scientific article published on 01 February 2001

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

scientific journal article

A new Cre recombinase gene based on optimal codon usage in mammals: a powerful material for organ-specific gene targeting

article

A newly cloned pig dolichyl-phosphate mannosyl-transferase for preventing the transmission of porcine endogenous retrovirus to human cells

scientific article

A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice

scientific article published on 26 July 2009

AMPD3-deficient mice exhibit increased erythrocyte ATP levels but anemia not improved due to PK deficiency

scientific journal article

Aberrant Distribution of ADAM3 in Sperm from Both Angiotensin-Converting Enzyme (Ace)- and Calmegin (Clgn)-Deficient Mice1

scientific article published on 26 July 2006

Acrosin Accelerates the Dispersal of Sperm Acrosomal Proteins during Acrosome Reaction

scientific article published in Journal of Biological Chemistry

Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs ⬇️

scientific article published on November 14, 2011

Activating transcription factor 5 is required for mouse olfactory bulb development via interneuron

scientific article published on 23 February 2015

Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells

scientific article published in May 2006

Adenovirus serotype 35 vector-mediated transduction into human CD46-transgenic mice

scientific article published on 16 March 2006

Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors.

scientific article

Amniotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells

scientific article published in January 2007

An enhancer unit of L-type pyruvate kinase gene is responsible for transcriptional stimulation by dietary fructose as well as glucose in transgenic mice

article

Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization.

scientific article published on 23 January 2005

Aromatase-null mice expressing enhanced green fluorescent protein in germ cells provide a model system to assess estrogen-dependent ovulatory responses

scientific article published on 22 November 2013

Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H, and cryptorchid mice

scientific article published on September 1999

Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus

scientific article published on 7 October 2008

Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility

scientific journal article

Capacitation-related changes in antigen distribution on mouse sperm heads and its relation to fertilization rate in vitro

scientific article published on 01 June 1987

Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart

scientific article published on 14 December 2001

Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse

scientific journal article

Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors

scientific article

Characterization of histone H2A.X expression in testis and specific labeling of germ cells at the commitment stage of meiosis with histone H2A.X promoter-enhanced green fluorescent protein transgene

scientific article published on 11 June 2003

Characterization of the testis-specific gene 'calmegin' promoter sequence and its activity defined by transgenic mouse experiments

scientific article

Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone ⬇️

scientific article published on December 19, 1997

Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.

scientific article

Collection of acrosome-reacted human sperm using monoclonal antibody-coated paramagnetic beads

scientific article published in August 1992

Comparative platelet anti-aggregant activity of D-cysteinolic acid analogues

scientific article published on 01 December 1989

Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.

scientific article published in January 2006

Complement regulation in the GalT KO era.

scientific article published on January 2010

Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer

article

Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery.

scientific article published in May 2001

Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)

scientific article published on February 1998

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress

scientific journal article

Depolarization-dependent survival of cultured mouse cerebellar granule neurons is strain-restrained

scientific article

Development of efficient strategies for the production of genetically modified pigs.

scientific article

Differential expression of CD43 isoforms on murine T cells and their relationship to acute intestinal graft versus host disease: studies using enhanced-green fluorescent protein transgenic mice

scientific article published on October 1999

Differential human serum-mediated neutralization of PERV released from pig cells transfected with variants of hDAF.

scientific article

Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse

scientific article

Disruption of the novel gene fad104 causes rapid postnatal death and attenuation of cell proliferation, adhesion, spreading and migration

scientific journal article

Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes

scientific article

Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

scientific journal article

E-cadherin-coated plates maintain pluripotent ES cells without colony formation

scientific article (publication date: 2006)

Effect of a monoclonal anti-mouse sperm antibody (OBF13) on the interaction of mouse sperm with zona-free mouse and hamster eggs

scientific article published on 01 August 1988

Effect of glucose and phloretin-2′-β-D-glucose (phloridzin) on in vitro fertilization of mouse ova

scientific article published on 01 April 1986

Efficient Derivation of Embryonic Stem Cells by Inhibition of Glycogen Synthase Kinase-3

scientific article published on 19 July 2007

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

scientific article

Efficient selection of transgenic mouse embryos using EGFP as a marker gene

scientific article published in September 1999

Establishment and analysis of SLC22A12 (URAT1) knockout mouse

scientific article published in June 2010

Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability

scientific article

Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system

scientific article

Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa

scientific article

Expression of complement regulatory protein on porcine endogenous retrovirus (PERV) depends on molecular size.

scientific article published on 10 March 2010

Expression of green fluorescent protein under beta-actin promoter in living spermatogenic cells of the mouse: stage-specific regulation by FSH

scientific article published on 01 August 2000

Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity ⬇️

scientific article published on November 1, 2001

FISH Analysis of 142 EGFP Transgene Integration Sites into the Mouse Genome

article

Fertilization: a sperm's journey to and interaction with the oocyte.

scientific article

Fetal microchimerism in the maternal mouse brain: a novel population of fetal progenitor or stem cells able to cross the blood-brain barrier?

scientific article published on 9 August 2005

Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation.

scientific article

Flow cytometric analysis of mouse sperm using monoclonal anti-sperm antibody OBF13.

scientific article published in September 1989

Formation of a thymus from rat ES cells in xenogeneic nude mouse↔rat ES chimeras.

scientific article published on 15 March 2011

Ftx is dispensable for imprinted X-chromosome inactivation in preimplantation mouse embryos.

scientific article published on 05 June 2014

Full reconstitution of hematopoietic system by murine umbilical cord blood.

scientific article published in June 2003

Function of the acrosomal matrix: zona pellucida 3 receptor (ZP3R/sp56) is not essential for mouse fertilization

scientific article published on 30 January 2012

Functional characterization of a mouse testicular olfactory receptor and its role in chemosensing and in regulation of sperm motility

scientific article

Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene

scientific article published in July 1998

GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice

scientific journal article

Generating green fluorescent mice by germline transmission of green fluorescent ES cells

scientific article published on August 1998

Generation of precise point mutation mice by footprintless genome modification.

scientific article

Genetic loss of Faah compromises male fertility in mice

scientific article

Ghrelin deficiency does not influence feeding performance.

scientific article published on 18 September 2007

Glucosamine enhanced sperm-egg binding but inhibited sperm-egg fusion in mouse

scientific article published on 01 February 1989

HANP1/H1T2, a novel histone H1-like protein involved in nuclear formation and sperm fertility

scientific article

Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage

scientific journal article

INAM plays a critical role in IFN-γ production by NK cells interacting with polyinosinic-polycytidylic acid-stimulated accessory cells.

scientific article published on 15 October 2014

Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse

scientific journal article

Identification of an imprinted gene cluster in the X-inactivation center

scientific article

Immunoglobulin-Secreting Cells of Maternal Origin Can Be Detected in B Cell-Deficient Mice1

scientific article published on 01 December 2000

Immunological behavior of enhanced green fluorescent protein (EGFP) as a minor histocompatibility antigen with a special reference to skin isograft and specific regulation of local graft-versus-host reaction (GvHR).

scientific article

Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2.

scientific article

Inconsistent reactivity of an anti-sperm monoclonal antibody and its relationship to sperm capacitation

scientific article

Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes

article

Induction of angiotensin-converting enzyme inhibitory activity by acid-limited proteolysis of glyceraldehyde 3-phosphate dehydrogenase

scientific article published on 01 June 1989

Induction of primordial germ cell-like cells from mouse embryonic stem cells by ERK signal inhibition

scientific article published in October 2014

Inefficient response of T lymphocytes to glycosylphosphatidylinositol anchor-negative cells: implications for paroxysmal nocturnal hemoglobinuria

article

Innate versus learned odour processing in the mouse olfactory bulb

scientific article published on 7 November 2007

Isolation of angiotensin-converting enzyme inhibitor from tuna muscle

scientific article published on 01 August 1988

L-amino acid oxidase plays a crucial role in host defense in the mammary glands

scientific article published on 10 March 2009

Lats2 is an essential mitotic regulator required for the coordination of cell division

scientific article published on 3 May 2007

Lessons Learned in Andrology: Seeing is believing

scientific article published on 01 January 2014

Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain

scientific article published in August 2004

Listeria monocytogenes-infected bone marrow myeloid cells promote bacterial invasion of the central nervous system

scientific article published in February 2005

Macrophage MHC and T-cell receptors essential for rejection of allografted skin and lymphoma

scientific article published in August 2013

Male infertility and the genetics of spermatogenesis

scientific article

Mammalian transgenesis by intracytoplasmic sperm injection

scientific article published in May 1999

Mechanism of host cell protection from complement in murine cytomegalovirus (CMV) infection: identification of a CMV-responsive element in the CD46 promoter region

scientific article

Mechanisms of fertilization elucidated by gene-manipulated animals

scientific article published in July 2015

Mechanisms of fertilization--a view from the study of gene-manipulated mice

scientific article published on 21 October 2010

Mechanisms of sperm-egg interactions emerging from gene-manipulated animals.

scientific article published in January 2008

Mechanisms of sperm-egg interactions emerging from gene-manipulated animals.

scientific article published on August 2007

Meichroacidin containing the membrane occupation and recognition nexus motif is essential for spermatozoa morphogenesis

scientific journal article

Membrane cofactor protein (MCP, CD46) in seminal plasma and on spermatozoa in normal and "sterile" subjects

scientific article published in June 1993

Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa ⬇️

scientific article published on May 23, 2012

Mice lacking Ran binding protein 1 are viable and show male infertility

article

Mice with Markedly Reduced PACAP (PAC1) Receptor Expression by Targeted Deletion of the Signal Peptide

scientific article published on 01 November 2000

Migration of exogenous immature hematopoietic cells into adult mouse brain parenchyma under GFP-expressing bone marrow chimera.

scientific article published in September 1999

Mili, a mammalian member of piwi family gene, is essential for spermatogenesis

scientific journal article

Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion

scientific article

Most fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization.

scientific article

Mouse germ cell-less as an essential component for nuclear integrity.

scientific article

Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg

scientific journal article

Multi-gene Gateway clone design for expression of multiple heterologous genes in living cells: Conditional gene expression at near physiological levels

article

N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability

scientific article published on 10 December 2012

NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility

scientific article published on 01 June 2020

Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells

scientific article published in February 2001

Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease

scientific article published in February 2008

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.

scientific article published on 26 September 2004

Non-invasive sexing of preimplantation stage mammalian embryos.

scientific article published in July 1998

Nonrandom X chromosome inactivation in mouse embryos carrying Searle's T(X;16)16H translocation visualized using X-linked LACZ and GFP transgenes

scientific article published on January 2002

Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice

scientific journal article

Novel method of gene transfer in birds: intracytoplasmic sperm injection for green fluorescent protein expression in quail blastoderms

scientific article published on 18 August 2010

Nuclear transfer of blastomeres expressing EGFP-reporter gene may improve the efficiency of transgenic cattle.

scientific article published in January 2001

ORP150 protects against hypoxia/ischemia-induced neuronal death

scientific article (publication date: March 2001)

Origins of intestinal intraepithelial lymphocytes: direct evidence for a thymus-derived gamma delta T cell component

scientific article published in December 2000

PGAP1 knock-out mice show otocephaly and male infertility

scientific article published on 20 August 2007

PGC7/Stella protects against DNA demethylation in early embryogenesis

scientific journal article

Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells

scientific article published in January 2004

Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis

scientific article published on 21 May 2006

Positive expression of the immunoglobulin superfamily protein IZUMO on human sperm of severely infertile male patients

article

Possible involvement of CD81 in acrosome reaction of sperm in mice

scientific article published in January 2008

Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

scientific article

Prevention of hyperacute rejection by phosphatidylinositol-anchored mini-complement receptor type 1

scientific article published on 01 June 1998

Production of mouse pups from germline transmission-failed knockout chimeras.

scientific article published on 24 July 2012

Production of transgenic pigs expressing human DAF (CD55) regulated by the porcine MCP gene promoter

article

Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation

scientific article published on 3 March 2005

Properties of recombinant hepatitis B vaccine

scientific article published in December 1987

Prophylaxis of antibody-induced acute glomerulonephritis with genetically modified bone marrow-derived vehicle cells

scientific article published in November 1999

Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction

scientific article published in October 2002

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].

scientific article

Rapid Compensation for Glycosylphosphatidylinositol Anchor Deficient Keratinocytes after Birth: Visualization of Glycosylphosphatidylinositol-Anchored Proteins in situ

scientific article published on 01 June 2002

Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein

scientific article published on 01 April 1999

Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis

scientific journal article

Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein

scientific article (publication date: 14 April 2000)

Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.

scientific article published on 2 August 2001

Requirement of CD9 on the egg plasma membrane for fertilization

scientific article published in January 2000

Restoration of spermatogenesis and fertility in azoospermic mutant mice by suppression and reelevation of testosterone followed by intracytoplasmic sperm injection

scientific article published in January 2002

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

scientific journal article

Role of the N-terminal domain of FliI ATPase in bacterial flagellar protein export

scientific article published on 25 January 2009

Role of the protomap and target-derived signals in the development of intrahemispheric connections

scientific article published on 20 April 2005

Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice.

scientific article

Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

scientific journal article

Small interfering RNA and gene silencing in transgenic mice and rats

scientific article published on December 2002

Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse

scientific journal article

Sperm from the Calmegin-Deficient Mouse Have Normal Abilities for Binding and Fusion to the Egg Plasma Membrane

scientific article published on 01 October 2002

Spermatocyte-Specific Gene Excision by Targeted Expression of Cre Recombinase

article

Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II

scientific article published on 01 March 1988

Survey of glycoantigens in cells from alpha1-3galactosyltransferase knockout pig using a lectin microarray

scientific article published in January 2010

Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery

scientific article published on 22 March 2011

Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors

scientific article published in April 2009

Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy

scientific article published on 18 March 2008

Tetraspanin-interacting protein IGSF8 is dispensable for mouse fertility.

scientific article published on 19 May 2012

The Acrosome Reaction: A Historical Perspective

scientific article published on January 2016

The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons

scientific journal article

The Regulation of Membrane Cofactor Protein (CD46) Expression by the 3′ Untranslated Region in Transgenic Mice

scientific article published on 01 April 1997

The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis

scientific article published on 24 May 2007

The cell biology of mammalian fertilization

scientific article

The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice

scientific article published in November 2000

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

scientific article

The mechanics clarifying counterclockwise rotation in most IVF eggs in mice.

scientific article

The mechanism of sperm–egg interaction and the involvement of IZUMO1 in fusion ⬇️

scientific article published on November 8, 2010

The regulation of membrane cofactor protein (CD46) expression in transgenic mice: The importance of the first 125 BP of the 3′ untranslated region

scientific article published on 01 February 1997

The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis

scientific article published in October 2006

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

scientific article

Tissue-dependent alteration of protease expression phenotype in murine peritoneal mast cells that were genetically labeled with green fluorescent protein

scientific article

Tissue-inherent fate of GPI revealed by GPI-anchored GFP transgenesis

scientific article

Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development.

scientific article published on July 1997

Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo.

scientific article

Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter

article

Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor

scientific article published in September 2004

Two independent pathways of maternal cell transmission to offspring: through placenta during pregnancy and by breast-feeding after birth

article

Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO1.

scientific article published on 3 September 2012

cHS4 insulator-mediated alleviation of promoter interference during cell-based expression of tandemly associated transgenes.

scientific article

miR-200b and miR-429 function in mouse ovulation and are essential for female fertility

scientific article

n-Hexane-Induced Synthesis of Hepatic Metallothionein Is Mediated by IL-6 in Mouse

scientific article published on 01 February 1994

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