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List of works by Michael C. Ostrowski

A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene.

scientific article

A flavoprotein responsible for the intense sulfhydryl oxidase activity of rat seminal vesicle secretion

scientific article published on March 1979

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

scientific article published on 12 September 2002

A new role for OPG: Putting RANKL in its place ⬇️

scientific article published on 01 September 2010

Allele-specific tumor spectrum in pten knockin mice

scientific article

Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.

scientific article published on 19 January 2009

An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites

scientific article published in July 1992

Analysis of the v-myb structural components important for transactivation of gene expression

scientific article published on April 1991

Anti-IL-6 and PD-L1 antibody combination therapy reduces tumor progression in murine models of pancreatic cancer.

scientific article published on 4 November 2015

Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells

scientific article

CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells

scientific article

CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth

scientific article

Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies

scientific article

Control of interferon-tau gene expression by Ets-2

scientific article

Covalent and noncovalent receptor-glucocorticoid complexes preferentially bind to the same regions of the long terminal repeat of murine mammary tumor virus proviral DNA.

scientific article published on December 1984

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells

scientific article

Cry protein crystals: a novel platform for protein delivery.

scientific article published on June 2015

Cyclic AMP-dependent activation of Rap1b

scientific article published on May 1995

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

article

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation

scientific article published in May 2017

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth

scientific article published on 26 October 2018

E2f1-3 are critical for myeloid development.

scientific article

E2f3 in tumor macrophages promotes lung metastasis

scientific article published on 9 November 2015

ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis

scientific article

Effect of castration on the synthesis of seminal vesicle secretory protein IV in the rat

scientific article published on 01 July 1982

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

scientific article

Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors

scientific article published on 2 April 2007

Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis

scientific article

Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter

scientific article

Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.

scientific article published on May 2009

Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer

scientific article (publication date: 2013)

Extra-embryonic function of Rb is essential for embryonic development and viability

scientific article published in February 2003

Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.

scientific article published on 05 December 2013

FGFR and PTEN signaling interact during lens development to regulate cell survival

scientific article published on 4 January 2016

Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.

scientific article

Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation

scientific article published on 03 May 2018

Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.

scientific article published on 2 January 2009

GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element

scientific article published in October 1996

Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele

scientific article published on 21 September 2017

Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.

scientific article published on 15 September 2016

Genetic and physical interactions between Microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation.

scientific article published on 31 July 2001

Genomic Alterations in Tumor Stroma

scientific article published on 25 August 2009

Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus

scientific article published on December 1981

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

scientific article

Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo

scientific article

Inhibitor κB kinase 2 is a myosin light chain kinase in vascular smooth muscle

scientific article published on July 2013

Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation.

scientific article published on March 1998

Isolation and characterization of minichromosome particles that contain a glucocorticoid-modulated promoter

scientific article

Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt.

scientific article published on 2 November 2005

Loss of fibroblast HIF-1α accelerates tumorigenesis.

scientific article

MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation

scientific article published on 02 April 2007

Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.

scientific article

MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation

scientific article

MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells

scientific article published on 3 June 2013

Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression

scientific article published on 13 April 2003

Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling

scientific article published on 15 January 2002

Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors

scientific article

NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model ⬇️

scientific article published on August 31, 2011

Nanofiber-expanded human CD34+ cells heal cutaneous wounds in streptozotocin-induced diabetic mice.

scientific article published on 10 June 2019

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

scientific article

Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.

scientific article

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis

scientific article published on 08 June 2021

PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway

scientific article published on 01 July 2002

PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.

scientific article published on June 2008

Properties of a flavoprotein sulfhydryl oxidase from rat seminal vesicle secretion.

scientific article

Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis

scientific article published on 23 April 2014

Pten in stromal fibroblasts suppresses mammary epithelial tumours

scientific article published on October 2009

Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.

scientific article

RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1.

scientific article published on 29 March 2004

Regulation of CSF-1 receptor expression

scientific article published on January 1997

Regulation of the murine TRACP gene promoter.

scientific article published on October 2003

Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

scientific article published on 18 December 2011

Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival

scientific article published on 29 November 2011

SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility

scientific article published on 28 March 2013

Setting Snail2's pace during EMT.

scientific article published in November 2012

Specific transcriptional initiation in vitro on murine type C retrovirus promoters ⬇️

scientific article published on July 1, 1981

Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways

scientific article published on 01 September 1996

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

scientific article published on September 2016

Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.

scientific article

Stromal PTEN determines mammary epithelial response to radiotherapy

scientific article published in Nature Communications

Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1

scientific article published on 31 October 2016

Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.

scientific article published on 04 June 2013

TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy

scientific article

Tensor classification of N-point correlation function features for histology tissue segmentation

scientific article

The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation

scientific article published on 18 July 2006

The ETS family of oncogenic transcription factors in solid tumours.

scientific article

The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma

scientific article

The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor

scientific article published on October 1991

The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor

scientific article

The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts

scientific article (publication date: March 2000)

The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).

scientific article

The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase

scientific article

The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling

scientific article published on May 1996

Transcription Factor ets-2 Plays an Important Role in the Pathogenesis of Pulmonary Fibrosis ⬇️

scientific article published on May 11, 2011

Transcription factor ATF3 links host adaptive response to breast cancer metastasis ⬇️

scientific article published on June 10, 2013

Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments

scientific article published on 10 November 2009

Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse

scientific article published on August 2006

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