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List of works by Paul N Moynagh

A poxviral homolog of the Pellino protein inhibits Toll and Toll-like receptor signalling.

scientific article published on 2 February 2011

Absence of MyD88 results in enhanced TLR3-dependent phosphorylation of IRF3 and increased IFN-β and RANTES production

scientific article published on 19 January 2011

Activation of NF-kappa B and induction of vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression in human glial cells by IL-1. Modulation by antioxidants

scientific article published on 01 September 1994

Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50

scientific article published on 17 September 2013

Antiinflammatory effects of glucocorticoids in brain cells, independent of NF-kappa B.

scientific article

CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis

scientific article published on 22 November 2020

CD40 employs p38 MAP kinase in IgE isotype switching

scientific article

Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways

scientific article

Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection.

scientific article published on 26 February 2013

Characterisation of expression patterns and functional role of Cactin in early zebrafish development

scientific article published on 27 March 2010

Chronic fluoxetine treatment attenuates post-septic affective changes in the mouse.

scientific article published on 8 October 2015

Contact sites and transport in mitochondria

scientific article published on January 1995

Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.

scientific article published on 15 June 2016

Dissection of tumor-necrosis factor-alpha inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early-but not late-phase LTP.

scientific article published in January 2004

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling

scientific article

Evidence for a role for the group I metabotropic glutamate receptor in the inhibitory effect of tumor necrosis factor-alpha on long-term potentiation

scientific article published on 2 January 2007

Functional conservation of an ancestral Pellino protein in helminth species

scientific article published on 29 June 2015

Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis

scientific article published on 29 August 2019

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis.

scientific article

HSV-1/TLR9-Mediated IFNβ and TNFα Induction Is Mal-Dependent in Macrophages

scientific article published on 18 December 2019

Hexachlorocyclohexanes inhibit steroidogenesis in Y1 cells. Absence of correlation with binding to the peripheral-type benzodiazepine binding site

scientific article published on May 1996

IL-15 in autoimmunity and cancer: O-tu-b or not O-tu-b?

scientific article published on 01 July 2019

Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses

scientific article

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis

scientific article

Immunological studies on the rat peripheral-type benzodiazepine acceptor

scientific article published on April 1991

In vivo binding of NF-kappaB to the IkappaBbeta promoter is insufficient for transcriptional activation

scientific article published on November 2006

Interleukin-1 activates transcription factor NF kappa B in glial cells

scientific article published on September 1993

Interleukin-1 and phorbol myristate acetate modulate the peripheral-type benzodiazepine receptor in lymphocytes and glial cells

scientific article published on September 1993

Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases

scientific article

Lipid peroxidation is involved in the activation of NF-kappaB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304. Lack of involvement of H2O2 in NF-kappaB activation by either cytokine in both primary and transf

scientific article published on October 1997

Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse.

scientific article

Long-lasting effects of sepsis on circadian rhythms in the mouse.

scientific article

Loss of Ikappa B-beta is associated with prolonged NF-kappa B activity in human glial cells.

scientific article

Mal mediates TLR-induced activation of CREB and expression of IL-10.

scientific article published on 11 March 2011

Mechanism of NF kappa B activation by interleukin-1 and tumour necrosis factor in endothelial cells

scientific article published on February 1996

Methods of detection of the transcription factor NF-kappa B in rat hippocampal slices

scientific article published in September 2002

Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity

scientific article published on July 2015

Molecular studies on the peripheral-type benzodiazepine acceptor

scientific article published on 01 August 1992

MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells

scientific article published on 8 September 2017

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

scholarly article

NF-κB signalling is involved in immune-modulation, but not basal functioning, of the mouse suprachiasmatic circadian clock

scientific article

Nitric oxide affects IL-6 expression in human peripheral blood mononuclear cells involving cGMP-dependent modulation of NF-κB activity

scientific article published on 16 March 2011

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

scientific article published on 30 December 2011

Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15

scientific article published on 19 July 2013

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses

scientific article published on 10 May 2019

Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions

scientific article

Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia

scientific article

PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent

scientific article published on January 1995

Parkin Impairs Antiviral Immunity by Suppressing the Mitochondrial Reactive Oxygen Species-Nlrp3 Axis and Antiviral Inflammation

scientific article published on 11 June 2019

Peli1 (rel)ieves autoimmunity ⬇️

scientific article published on September 20, 2011

Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner

scientific article

Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α

scientific article

Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons

scientific journal article

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis

scientific journal article

Persistent interleukin-1beta signaling causes long term activation of NFkappaB in a promoter-specific manner in human glial cells

scientific article published on 2 February 2006

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

scholarly article

Purification and immunological studies on the peripheral type benzodiazepine acceptor

scientific article published on 01 February 1991

RIP kinases: key decision makers in cell death and innate immunity

scientific article

Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress

scientific article published on 07 November 2019

Rapid polarization of Th2 cells during induction of antigen-specific IgE antibodies in vitro

scientific article published on 01 September 2000

Regulation of Toll-like receptor 4 signalling by A20 zinc finger protein

scientific article published on April 2003

Regulatory T cells promote myelin regeneration in the central nervous system.

scientific article published on 13 March 2017

Stabilization of the peripheral-type benzodiazepine acceptor by specific phospholipids

scientific article published in May 1992

TNF-alpha is a mediator of the anti-inflammatory response in a human neonatal model of the non-septic shock syndrome

scientific article

Temporal change in gene expression in the rat dentate gyrus following passive avoidance learning

scientific article published on 9 February 2007

The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.

scientific article published on 19 April 2018

The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance.

scientific article published on 29 November 2014

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling

scientific article published on 10 September 2006

The human endothelial cell line ECY304 as a model of endothelial cell activation by interleukin-1.

scientific article published on February 1995

The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells

scientific article

The interleukin-1 signalling pathway in astrocytes: a key contributor to inflammation in the brain

scientific article

The peripheral-type benzodiazepine receptor is present in astrocytes but is not a primary site of action for convulsants/anticonvulsants

scientific article published on 01 February 1994

The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes

scientific article published on 22 January 2013

The roles of Pellino E3 ubiquitin ligases in immunity

scientific article published on 21 January 2014

The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner

scientific article published on 16 August 2005

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.

scientific article

Toll-like receptor signalling pathways as key targets for mediating the anti-inflammatory and immunosuppressive effects of glucocorticoids

scientific article published on 01 November 2003

Tumour-necrosis-factor-receptor-associated factor 6, NF-kappaB-inducing kinase and IkappaB kinases mediate IgE isotype switching in response to CD40.

scientific article published on September 2000

Uncoupled turnover disrupts mitochondrial quality control in diabetic retinopathy

scientific article published on 05 December 2019

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