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List of works by Franca Esposito

A new p21waf1/cip1 isoform is an early event of cell response to oxidative stress

article

A p53-independent Pathway for Activation of WAF1/CIP1 Expression Following Oxidative Stress

scientific article published in Journal of Biological Chemistry

AROS-29 is involved in adaptive response to oxidative stress

scientific article

Adaptation to oxidative stress, chemoresistance, and cell survival

scientific article

Amyloid fibrils derived from the apolipoprotein A1 Leu174Ser variant contain elements of ordered helical structure

scientific article

Chapter 8 Biochemical Correlations Between Pseudouridine Excretion and Neoplasias

Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer

scientific article published on 30 March 2020

Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone

scientific article

DNA binding activity of the glucocorticoid receptor is sensitive to redox changes in intact cells.

scientific article published on February 1995

DNA sequence specificity of 4,5',8-trimethylpsoralen cross-linking. Effect of neighboring bases on cross-linking the 5'-TA dinucleotide

scientific article published in Journal of Biological Chemistry

DNA supercoiling and eukaryotic gene expression

scientific article

Determination of pseudouridine and other nucleosides in human blood serum by high-performance liquid chromatography.

scientific article published on April 1983

Differentially expressed mRNAs as a consequence of oxidative stress in intact cells.

scientific article published on September 1995

Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance

scientific article published on 16 February 2019

Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas

scientific article published on 24 December 2019

Gene regulation by reactive oxygen species

scientific article published on January 1997

Generation of prooxidant conditions in intact cells to induce modifications of cell cycle regulatory proteins

scientific article

HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy

scientific article published on 03 June 2019

Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy

scientific article

IDH1 Targeting as a New Potential Option for Intrahepatic Cholangiocarcinoma Treatment-Current State and Future Perspectives

scientific article published on 18 August 2020

In budding yeast, reactive oxygen species induce both RAS-dependent and RAS-independent cell cycle-specific arrest

article

Inhibition of NADH/NADPH oxidase affects signal transduction by growth factor receptors in normal fibroblasts

scientific article published in January 2002

Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion

scientific article published on August 1994

Insulin-resistant conditions: A favorable milieu for aggressive drug-resistant malignancies

scientific article

Isolation and structural characterization of the rat gene encoding the brain specific snRNP-associated polypeptide "N"

scientific article

Low-affinity receptor-mediated induction of superoxide by N-formyl-methionyl-leucyl-phenylalanine and WKYMVm in IMR90 human fibroblasts

scientific article published on January 2004

Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides

scientific article published on 29 September 2014

Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression

scientific article published on 30 July 2019

Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents.

scientific article published on 20 July 2010

Modified nucleosides in body fluids of tumor-bearing patients

scientific article published on 01 January 1983

Modulation of Mitochondrial Metabolic Reprogramming and Oxidative Stress to Overcome Chemoresistance in Cancer

scientific article published on 14 January 2020

New insights into TRAP1 pathway

scientific article published on 19 February 2012

Oxidative DNA damage and activation of c-Jun N-terminal kinase pathway in fibroblasts from patients with hereditary spastic paraplegia

scientific article published in December 2005

Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer

scientific article published on 20 May 2016

Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity

scientific article published on 7 April 2003

Pseudouridine excretion and transfer RNA primers for reverse transcriptase in tumors of retroviral origin.

scientific article

Redox control of signal transduction, gene expression and cellular senescence

scientific article published on March 2004

Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

scientific article published on 01 May 1997

Regulation of p21waf1/cip1 expression by intracellular redox conditions

scientific article published in July 2001

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo

scientific article

Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1.

scientific article published on 2 May 2013

Retinoblastoma protein dephosphorylation is an early event of cellular response to prooxidant conditions

article

Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis

scientific article

Structure and in vitro transcription of tRNA gene clusters containing the primers of MuLV reverse transcriptase

scientific article

Supercoiling in prokaryotic and eukaryotic DNA: changes in response to topological perturbation of plasmids in E. coli and SV40 in vitro, in nuclei and in CV-1 cells

scientific article

TRAP1 Regulates Wnt/β-Catenin Pathway through LRP5/6 Receptors Expression Modulation

scientific article published on 13 October 2020

TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor.

scientific article

TRAP1 and SORCIN cooperate in a survival pathway responsible for inducing drug-resistance in human colorectal carcinoma (CRC).

scientific article published on 24 September 2010

TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins

scientific article published on 7 October 2011

TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways

scientific article published on 10 June 2015

TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors

scientific article published on 19 September 2014

TRAP1 regulates cell cycle and apoptosis in thyroid carcinoma cells.

scientific article published on 15 July 2016

TRAP1 revisited: novel localizations and functions of a 'next-generation' biomarker (review).

scientific article published on 27 June 2014

TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells

scientific article published on 29 November 2013

TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells

scientific article published on 12 February 2009

TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors

scientific article published on 13 June 2014

Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma

scientific article published on 13 June 2015

The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism

scientific article

The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis

scientific article published on 6 February 2007

The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase

scientific article

The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei

scientific article published on 26 January 2011

Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1

scientific article

Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis

scientific article published on November 2007

Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway

scientific article published on 27 July 2016

Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association

scientific article published on 23 October 2013

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