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List of works by Karen E Cosgrove

A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland

scientific article published in February 1999

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line

scientific article

Abnormal Neurodevelopmental Outcomes are Common in Children with Transient Congenital Hyperinsulinism

scientific article published on 20 May 2013

Affinity isolation of imidazoline binding proteins from rat brain using 5-amino-efaroxan as a ligand

scientific article published in March 1999

Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel

scientific article

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism

scientific article published on November 2002

Can network biology unravel the aetiology of congenital hyperinsulinism?

scientific article

Characterization of ion channels in stimulus-secretion coupling in pancreatic islets

scientific article published on January 1997

Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy

scientific article

From congenital hyperinsulinism to diabetes mellitus: the role of pancreatic beta-cell KATP channels.

scientific article

Genetics and pathophysiology of hyperinsulinism in infancy.

scientific article published on 20 February 2004

Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

scientific article published on March 2000

Human embryonic stem cells: possibilities for human cell transplantation.

scientific article

Hyperinsulinemic Hypoglycemia in Beckwith-Wiedemann Syndrome due to Defects in the Function of Pancreatic β-Cell Adenosine Triphosphate-Sensitive Potassium Channels

scientific article published on 05 April 2005

Hyperinsulinism in infancy: from basic science to clinical disease.

scientific article published on January 2004

Hyperinsulinism of infancy: novel ABCC8 and KCNJ11 mutations and evidence for additional locus heterogeneity

scientific article published in December 2004

Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

scientific article

Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy.

scientific article

In vitro recovery of ATP-sensitive potassium channels in β-cells from patients with congenital hyperinsulinism of infancy ⬇️

scientific article

Increased Plasma Incretin Concentrations Identifies a Subset of Patients with Persistent Congenital Hyperinsulinism without KATP Channel Gene Defects

article

Infantile hyperinsulinism associated with enteropathy, deafness and renal tubulopathy: clinical manifestations of a syndrome caused by a contiguous gene deletion located on chromosome 11p.

scientific article published in December 2004

Integrating genetic and imaging investigations into the clinical management of congenital hyperinsulinism.

scientific article published on June 2013

Network analysis: a new approach to study endocrine disorders

scientific article

PAX4 enhances beta-cell differentiation of human embryonic stem cells

scientific article published in 2008

Potassium Channels, Sulphonylurea Receptors and Control of Insulin Release

scientific article published on 01 May 1999

Reduced Glycemic Variability in Diazoxide-Responsive Children with Congenital Hyperinsulinism Using Supplemental Omega-3-Polyunsaturated Fatty Acids; A Pilot Trial with MaxEPA(R.).

scientific article published on 12 March 2014

The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism

article

Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels.

scientific article published in December 2002

Verapamil, a phenylalkylamine Ca 2 + channel blocker, inhibits ATP-sensitive K + channels in insulin-secreting cells from rats

scientific article published on 01 December 1997

Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells

scientific article published on February 2004

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