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List of works by David G. Fernig

A Generic Approach to Monofunctionalized Protein-Like Gold Nanoparticles Based on Immobilized Metal Ion Affinity Chromatography

scientific article published on 01 April 2006

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer's Disease.

scientific article published on 16 May 2019

A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome ⬇️

scientific article published on March 30, 2011

A basic peptide derived from the HARP C-terminus inhibits anchorage-independent growth of DU145 prostate cancer cells

scientific article published on 7 August 2007

A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra.

scientific article published in October 2014

A rapid procedure for production of human basic fibroblast growth factor in Escherichia coli cells.

scientific article published in July 1992

ANG-1 TIE-2 and BMPR signalling defects are not seen in the nitrofen model of pulmonary hypertension and congenital diaphragmatic hernia

scientific article

Adsorption of Calf Thymus DNA on Au(110) Studied by Reflection Anisotropy Spectroscopy

article

Airway Smooth Muscle Dysfunction Precedes Teratogenic Congenital Diaphragmatic Hernia and May Contribute to Hypoplastic Lung Morphogenesis

scientific article published on 25 May 2006

Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network.

scientific article published on 13 March 2013

Appearance of basic fibroblast growth factor receptors upon differentiation of rat mammary epithelial to myoepithelial-like cells in culture

scientific article published on January 1990

Array-based functional screening of heparin glycans

scientific article published on May 2012

Attachment of glycosaminoglycan oligosaccharides to thiol-derivatised gold surfaces

scientific article published on 11 October 2004

Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka)

scientific article (publication date: 7 September 2001)

Biocompatible Peptide-Coated Ultrasmall Superparamagnetic Iron Oxide Nanoparticles for In Vivo Contrast-Enhanced Magnetic Resonance Imaging

scientific article published on 11 July 2018

Bipartite design of a self-fibrillating protein copolymer with nanopatterned peptide display capabilities.

scientific article

Cathepsin L digestion of nanobioconjugates upon endocytosis

scientific article published in September 2009

Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution

scientific article published in June 2009

Chapter 5 - Detection of antimycolic acid antibodies by liposomal biosensors.

scientific article published in January 2009

Characterisation of membrane mimetics on a dual polarisation interferometer

scientific article published on 10 March 2006

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

scientific article

Cobalt nanoparticles as a novel magnetic resonance contrast agent--relaxivities at 1.5 and 3 Tesla

scientific article

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships

scientific article published on 3 September 2010

Cytokines and growth factors cross-link heparan sulfate ⬇️

scientific article

Degradation of nuclear proteins: studies on transplanted B82 cell karyoplast proteins

scientific article published on 01 January 1987

Determination of size and concentration of gold nanoparticles from UV-vis spectra

scientific article

Determination of the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces using reflection anisotropy spectroscopy.

scientific article published in January 2009

Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis

scientific article published on 2 December 2004

Differential Regulation of FGF-1 and -2 Mitogenic Activity Is Related to Their Kinetics of Binding to Heparan Sulfate in MDA-MB-231 Human Breast Cancer Cells

scientific article published on 01 January 2000

Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes

scientific article

Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors

scientific article published on 24 August 2001

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity

scientific article published on May 2010

Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility.

scientific article

Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity

scientific article

Ectopic production of heparin-binding growth factors and receptors for basic fibroblast growth factor by rat mammary epithelial cell lines derived from malignant metastatic tumours

scientific article

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import

scientific article published in Journal of Biological Chemistry

Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk

scientific article published on 16 July 2019

Enhanced inhibition of influenza virus infection by peptide-noble metal nanoparticle conjugates

Enhanced inhibition of influenza virus infection by peptide-noble-metal nanoparticle conjugates

scientific article published on 14 May 2019

Evaluation of biosensor surfaces for the detection of microtubule perturbation

scientific article published on 17 June 2009

Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis

scientific article published on 18 October 2010

Expression and purification of an FGF9 fusion protein in E. coli, and the effects of the FGF9 subfamily on human hepatocellular carcinoma cell proliferation and migration.

scientific article published on 18 September 2017

Extracellular interactome of the FGF receptor-ligand system: complexities and the relative simplicity of the worm

scientific article published on February 2009

Fabrication of carbohydrate surfaces by using nonderivatised oligosaccharides, and their application to measuring the assembly of sugar-protein complexes

scientific article

Facile synthesis of stable, water-soluble magnetic CoPt hollow nanostructures assisted by multi-thiol ligands

Fibroblast Growth Factor Receptors 1 and 2 Interact Differently with Heparin/Heparan Sulfate

scientific article published in Journal of Biological Chemistry

Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts

scientific article

Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair

scientific article published on January 1994

Fibroblast growth factors as tissue repair and regeneration therapeutics

scientific article

Following Protein–Glycosaminoglycan Polysaccharide Interactions with Differential Scanning Fluorimetry

scientific article published on 01 January 2012

Functional examination of novel kisspeptin phosphinic peptides.

scientific article

Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression

scientific article published in 2022

Glycans: pervasive regulators of protein and cellular function

Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra

article

Glycosaminoglycans differentially bind HARP and modulate its biological activity

scientific article published on March 1999

Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain

scientific article published on 30 April 2020

Growth factors and their receptors in neoplastic mammary glands

scientific article

HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors

scientific article published on 25 June 2015

Heparan Sulfate Surfaces to Probe the Functions of the Master Regulator of the Extracellular Space

Heparan sulfate in lung morphogenesis: The elephant in the room

scientific article published on March 2010

Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities

scientific article published on December 2009

Heparin and in-vitro experimental lung hypoplasia

scientific article published on January 2000

Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification

scientific article

Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin

scientific article published on 29 April 2020

Hepatocyte Growth Factor/Scatter Factor Has Distinct Classes of Binding Site in Heparan Sulfate from Mammary Cells ⬇️

scientific article published on April 28, 1998

Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes

scientific article

Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.

scientific article

Heterodimeric interaction and interfaces of S100A1 and S100P

scientific article

High colloidal stability of gold nanorods coated with a peptide-ethylene glycol: Analysis by cyanide-mediated etching and nanoparticle tracking analysis.

scientific article published on 5 July 2016

High production in E. coli of biologically active recombinant human fibroblast growth factor 20 and its neuroprotective effects

scientific article

High-level production of human acidic fibroblast growth factor in E. coli cells: Inhibition of DNA synthesis in rat mammary fibroblasts at high concentrations of growth factor ⬇️

scientific article published on September 28, 1990

Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex.

scientific article

Identification of alpha transforming growth factor as a possible local trophic agent for the mammary gland

scientific article published on 01 November 1989

Identification of cell types in the developing goat mammary gland

scientific article published in June 1999

Identification of heparin-binding sites in proteins by selective labeling

scientific article

In silico analyses of heparin binding proteins expression in human periodontal tissues

scientific article published on 28 January 2016

In vitro effects of growth factors on lung hypoplasia in a model of congenital diaphragmatic hernia

article

Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives

scientific article published on 18 June 2007

Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain

scientific article

Insulin processing in primary endosomes is not responsible for insulin resistance observed in parametrial adipocytes from lactating rats

scientific article published on 01 February 1989

Interaction of heparan sulfate from mammary cells with acidic fibroblast growth factor (FGF) and basic FGF. Regulation of the activity of basic FGF by high and low affinity binding sites in heparan sulfate

scientific article

Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy.

scientific article

Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches

scientific article published on 12 January 2004

Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density.

scientific article published on 21 December 2007

Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.

scientific article published on 4 February 2005

Interactions of proteins with heparan sulfate

scientific article published in 2024

Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides

scientific article published on April 1998

Intracellular trafficking and release of intact edible mushroom lectin from HT29 human colon cancer cells

scientific article published on 01 April 2000

Kinase-catalyzed modification of gold nanoparticles: a new approach to colorimetric kinase activity screening

scientific article published in February 2006

Late signals are required for the stimulation of DNA synthesis in rat mammary fibroblasts by growth factors

scientific article published on June 1996

Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?

scientific article published on 24 February 2012

Modulation of mammary development and programmed cell death by the frequency of milk removal in lactating goats

article

Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

scientific article published on 01 November 2014

Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes

N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo

scientific article published on 02 October 2009

N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding

scientific article

Network based meta-analysis prediction of microenvironmental relays involved in stemness of human embryonic stem cells

scientific article published on 23 October 2014

Neuropilins: a versatile partner of extracellular molecules that regulate development and disease

scientific article published on May 2008

New tools for carbohydrate sulfation analysis: heparan sulfate 2--sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors

article

New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

article

One-step synthesis of monodisperse water-soluble ‘dual-responsive’ magnetic nanoparticles

scientific article published on 16 October 2007

Optical biosensor techniques to analyze protein-polysaccharide interactions.

scientific article published on January 2001

Orientation of Ordered Structures of Cytosine and Cytidine5′-Monophosphate Adsorbed at Au(110)/Liquid Interfaces

scientific article published in Physical Review Letters

Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a ‘mixed matrix’

article by Neill J Liptrott et al published November 2014 in Nanomedicine

Peptides as capping ligands for in situ synthesis of water soluble Co nanoparticles for bioapplications

Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth

scientific article published on 07 April 2006

Photothermal absorption correlation spectroscopy.

scientific article published in February 2009

Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells

scientific article

Presentation of IFN- to Nitric Oxide-Producing Cells: A Novel Function for Mast Cells

scientific article published on 01 January 2000

Prevention of surface reconstruction at the Au(110)/electrolyte interface by the adsorption of cytosine.

scientific article published in June 2010

Programmed cell death in bovine mammary tissue during lactation and involution

scientific article published on 01 September 1997

Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide

scientific article published on 12 October 2014

Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes.

scientific article

RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin

scientific journal article

Rat mammary myoepithelial-like cells in culture possess kinetically distinct low-affinity receptors for fibroblast growth factor that modulate growth stimulatory responses

scientific article published on January 1992

Rational and combinatorial design of peptide capping ligands for gold nanoparticles

scientific article

Real-time monitoring of the development and stability of biofilms of Streptococcus mutans using the quartz crystal microbalance with dissipation monitoring

scientific article

Reflection Anisotropy Spectroscopy Study of the Adsorption of Sulfur-Containing Amino Acids at the Au(110)/Electrolyte Interface

article

Robust ligand shells for biological applications of gold nanoparticles.

scientific article

S100P dissociates myosin IIA filaments and focal adhesion sites to reduce cell adhesion and enhance cell migration

scientific article

SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins

scientific article published on 30 April 2020

Secretion of transforming growth factor alpha and expression of its receptor in human mammary cell lines

scientific article published on January 1994

Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix.

scientific article

Self-association of calcium-binding protein S100A4 and metastasis

scientific article

Silver and gold nanoparticle-coated membranes for femtomole detection of small proteins and peptides by Dot and Western blot

scientific article published on 20 December 2006

SimpleDSFviewer: A tool to analyze and view differential scanning fluorimetry data for characterizing protein thermal stability and interactions

scientific article published on 19 August 2019

Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques

scientific article published on 28 December 2007

Size and shape control for water-soluble magnetic cobalt nanoparticles using polymer ligands

scholarly article by Le Trong Lu et al published 2008 in Journal of Materials Chemistry

Specific Internalisation of Gold Nanoparticles into Engineered Porous Protein Cages via Affinity Binding

scientific article

Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung

scientific article published on 12 May 2005

Stem cells in breast epithelia

scientific article published in August 1998

Structural determinants of heparin-transforming growth factor-β1 interactions and their effects on signaling

scientific article published on 24 August 2015

Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?

scientific article

Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation

scientific article published on 16 July 2019

Supramolecular domains in mixed peptide self-assembled monolayers on gold nanoparticles

scientific article published in September 2008

Synthesis of basic fibroblast growth factor upon differentiation of rat mammary epithelial to myoepithelial-like cells in culture

scientific article

Targeting Cell Membrane Lipid Rafts by Stoichiometric Functionalization of Gold Nanoparticles With a Sphingolipid-Binding Domain Peptide

scientific article published on 3 February 2015

The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding

scientific article (preprint)

The C-terminal region of S100A4 is important for its metastasis-inducing properties

scientific journal article

The Peptide Route to Multifunctional Gold Nanoparticles

scientific article published on 01 May 2005

The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation.

scientific article published on January 2008

The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis

scientific article published on 10 September 2008

The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans.

scientific article

The crystal structure at 2A resolution of the Ca2+ -binding protein S100P

scientific article

The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

scientific article

The heparin-binding protein interactome in pancreatic diseases

scientific article published on 26 August 2013

The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis.

scientific article published on 18 June 2019

The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.

scientific article

The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids

article

Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate

scientific article (publication date: July 2012)

Use of a biosensor to determine the binding kinetics of five lectins for Galactosyl-N-acetylgalactosamine

scientific article published in July 2001

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