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List of works by Jean-Baptiste Demoulin

A minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers

scientific article

ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines

scientific article (publication date: 2014)

ABCB1 1199G>A polymorphism (rs2229109) affects the transport of imatinib, nilotinib and dasatinib.

scientific article published on 7 June 2016

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.

scientific article

Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.

scientific article published on 2 March 2004

CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

scientific article published in February 2003

Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway

scientific article published on 11 March 2014

Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein

scientific article

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9

scientific article (publication date: 3 September 1999)

ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic progenitor cell proliferation and differentiation into eosinophils: the role of nuclear factor-κB.

scientific article published on 22 January 2012

FOXO transcription factors in cancer development and therapy

scientific article published on 19 December 2015

Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition

scientific article published on December 2011

Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor

scientific article published on 17 February 2004

Global microRNA profiling of well-differentiated small intestinal neuroendocrine tumors.

scientific article

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation

scientific article published on 17 January 2018

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets

scientific article

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

scientific article published on 5 May 2016

Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling

scientific article published on 8 October 2014

Impact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib

scientific article published on 12 July 2016

Inflammation-induced cholestasis in cancer cachexia

scientific article published on 22 December 2020

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling

scientific article published in 2000

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

scientific article published on 19 October 2005

JAK2, the JAK2 V617F mutant and cytokine receptors.

scientific article

KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia

scientific article published on 18 February 2010

Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis

scientific article published on April 2009

Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.

scientific article published in December 2003

MAP kinase activation by interleukin-9 in lymphoid and mast cell lines

scientific article published on March 2003

Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

scientific article

New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases

scientific article published on 25 June 2010

No PDGF receptor signal in pericytes without endosialin?

scientific article

Novel COL4A1-VEGFD gene fusion in myofibroma

scientific article published on 08 April 2021

Novel head-to-head gene fusion of MLL with ZC3H13 in a JAK2 V617F-positive patient with essential thrombocythemia without blast cells

article

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

scientific article

Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes

scientific article published on 25 October 2010

Oxidative DNA damage by t-butyl hydroperoxide causes DNA single strand breaks which is not linked to cell lysis. A mechanistic study in freshly isolated rat hepatocytes

scientific article published on 01 October 1995

PDGF receptor signaling networks in normal and cancer cells

scientific article published on 19 March 2014

PDGF-D expression is down-regulated by TGFβ in fibroblasts

scientific article

PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase

scientific article

PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations

scientific article published on 10 June 2013

PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib

scientific article published on 12 October 2015

PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies

scientific article published on 3 November 2011

Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors

scientific article published on 30 December 2010

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

scientific article

Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis

scientific article published on 25 August 2011

Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis

scientific article published on January 2012

Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways

scientific article

Review of current classification, molecular alterations, and tyrosine kinase inhibitor therapies in myeloproliferative disorders with hypereosinophilia

scientific article published on 09 August 2013

Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation

scientific article published on 01 October 2000

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

scientific article

Scleroderma

scientific article published on 20 August 2009

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

scientific article published on 4 April 2017

The HMG box transcription factor HBP1: a cell cycle inhibitor at the crossroads of cancer signaling pathways

scientific article published on 25 January 2019

The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway

scientific article published on May 2014

The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation

scientific article

The gene expression profile of PDGF-treated neural stem cells corresponds to partially differentiated neurons and glia

scientific article published in September 2006

The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells

scientific article

The t(11;19)(q23;p13) fusing MLL with MYO1F is recurrent in infant acute myeloid leukemias

scientific article published on 26 May 2011

The t(1;9)(p34;q34) fusing ABL1 with SFPQ, a pre-mRNA processing gene, is recurrent in acute lymphoblastic leukemias.

scientific article

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

scientific article published on 24 February 2009

The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.

scientific article published on 17 February 2014

Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms

scientific article

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

scientific article

Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies

scientific article published on February 2012

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