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List of works by Andreas S Madsen

A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

scientific article published on 20 January 2016

An NAD+-Dependent Sirtuin Depropionylase and Deacetylase (Sir2La) from the Probiotic Bacterium Lactobacillus acidophilus NCFM

scientific article published on 13 June 2018

Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities

scientific article published on 31 August 2017

Effective Modulation of DNA Duplex Stability by Reversible Transition Metal Complex Formation in the Minor Groove

scientific article published on 07 July 2007

Enzymatic polymerisation involving 2′-amino-LNA nucleotides

scientific article published on 28 March 2012

Functionalization of 2'-amino-LNA with additional nucleobases.

scientific article published on 19 March 2009

Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.

scientific article

Histone Deacetylase 11 Is an ε-N-Myristoyllysine Hydrolase

scientific article published on 03 May 2018

Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA.

scientific article published on 25 September 2013

Innovative Strategies for Selective Inhibition of Histone Deacetylases

scientific article

Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH

scientific article published on 9 February 2016

LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis

scientific article published on 3 September 2010

Large Scale Synthesis of 2′-Amino-LNA Thymine and 5-Methylcytosine Nucleosides

scientific article published on 26 November 2012

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

scientific article

Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight

scientific article published on 17 October 2017

Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites

scientific article published on 19 August 2008

Oligonucleotides with 1,4-Dioxane-Based Nucleotide Monomers

scientific article published on 02 April 2012

Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA.

scientific article

Optoepigenetics: An acetylation photoswitch

scientific article published on 14 March 2016

Profiling of substrates for zinc-dependent lysine deacylase enzymes: HDAC3 exhibits decrotonylase activity in vitro

scientific article published on 13 August 2012

Pyrene-perylene as a FRET pair coupled to the N2'-functionality of 2'-amino-LNA.

scientific article published on 3 May 2007

Recognition of double-stranded DNA using energetically activated duplexes with interstrand zippers of 1-, 2- or 4-pyrenyl-functionalized O2'-alkylated RNA monomers

scientific article

SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion

scientific article

Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme

scientific article published on 24 May 2012

Synthesis and Hybridization Studies of 2‘-Amino-α-L-LNA and Tetracyclic “Locked LNA”†

scientific article published on 01 May 2006

Synthesis and biophysical studies of N2'-functionalized 2'-amino-alpha-L-LNA.

scientific article published in January 2007

Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3′- O ,4′- C -methylene-linked α- l -ribonucleotides

scientific article published on 18 May 2006

The effect of various zinc binding groups on inhibition of histone deacetylases 1-11.

scientific article published on 27 December 2013

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