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List of works by Kurt J De Vos

A caspase-activated factor (CAF) induces mitochondrial membrane depolarization and cytochrome c release by a nonproteolytic mechanism.

scientific article published on December 1998

A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function

scientific article

ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.

scientific article published on 14 July 2016

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

scientific article published on 24 February 2010

Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels

scientific article published on 14 September 2017

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria ⬇️

scientific article published on January 17, 2012

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

scientific article published on November 1998

Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish.

scientific article

C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten

scientific article

C9orf72 expansion disrupts ATM-mediated chromosomal break repair.

scientific article

C9orf72 plays a central role in Rab GTPase-dependent regulation of autophagy.

scientific article published on 21 October 2016

Cell-free assays for mitochondria-cytoskeleton interactions.

scientific article published on January 2007

Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-β Production ⬇️

scientific article published on January 1, 2010

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

scientific journal article

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity ⬇️

scientific article published on August 29, 1995

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

scientific article

Expression of phosphatidylinositol (4,5) bisphosphate-specific pleckstrin homology domains alters direction but not the level of axonal transport of mitochondria.

scientific article published on 11 July 2003

Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

scientific article published on 28 August 2007

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

scientific article

Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention.

scientific article

Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo

scientific article published on 26 September 2011

Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission

scientific article published in April 2005

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

scientific article (publication date: 27 February 2009)

Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?

scientific article published on 21 February 2017

Neurofilament subunit (NFL) head domain phosphorylation regulates axonal transport of neurofilaments.

scientific article published on 14 January 2009

Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

scientific article

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

scientific article published on 9 October 2015

Riluzole protects against glutamate-induced slowing of neurofilament axonal transport.

scientific article published on 3 March 2009

Role of axonal transport in neurodegenerative diseases

scientific article

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

scientific article

The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region

scientific article published on April 1998

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

scientific article published on 22 June 2016

The role of mitochondria in amyotrophic lateral sclerosis

scientific article published on 29 June 2017

Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration

scientific article

Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria

scientific article

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

scientific article

Visualization and quantification of mitochondrial dynamics in living animal cells.

scientific article published on January 2007

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