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List of works by Eduard Stefan

A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle

scientific journal article

BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS

scientific article published on 14 August 2019

Calcium-dependent binding of Myc to calmodulin.

scientific article published on December 2016

Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells

scientific article published on 29 November 2006

Compartmentalized cAMP signalling regulates vasopressin-mediated water reabsorption by controlling aquaporin-2.

scientific article

Control of PKA stability and signalling by the RING ligase praja2

scientific article

Corrigendum: Impact of kinase activating and inactivating patient mutations on binary PKA interactions

scientific article published on 24 September 2015

Counterregulation of cAMP-directed kinase activities controls ciliogenesis.

scientific article published on 26 March 2018

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

scientific article

Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.

scientific article published on 12 June 2019

Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling

scientific article published on 28 June 2016

Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium

scientific article published on 03 January 2020

High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides

scientific article published on June 2006

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin

scientific article

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells

scientific journal article

Impact of kinase activating and inactivating patient mutations on binary PKA interactions

scientific article published on 18 August 2015

In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs

scientific article published on 23 June 2015

Inhibitor of MYC identified in a Kröhnke pyridine library

scientific article

Interplay of PKA and Rac: fine-tuning of Rac localization and signaling

scientific article

KinCon: Cell-based recording of full-length kinase conformations

scientific article published on 06 February 2020

MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer

scientific article published on 3 May 2017

Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies

scientific article published on 23 November 2020

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

scientific article published on 20 December 2011

Phosphorylation of Protein Kinase A (PKA) regulatory subunit RIα by Protein Kinase G (PKG) primes PKA for catalytic activity in cells

scientific article

Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.

scientific article published on January 2013

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo

scholarly article

Reciprocal regulation of PKA and Rac signaling ⬇️

scientific article published on May 8, 2013

Removal of the carboxy terminus of the A2A-adenosine receptor blunts constitutive activity: differential effect on cAMP accumulation and MAP kinase stimulation

scientific article published on 28 August 2002

Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells

scientific journal article

Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.

scientific article published on 4 November 2016

Systematic Quantification of GPCR/cAMP-Controlled Protein Kinase A Interactions

scientific article

Systematic identification of signal integration by protein kinase A.

scientific article

Targeting the Architecture of Deregulated Protein Complexes in Cancer.

scientific article published on 18 August 2017

The many faces of compartmentalized PKA signalosomes.

scientific article

The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor

scientific article

Zebrafish Cxcr4a determines the proliferative response to Hedgehog signalling

scientific article published in August 2012

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

scientific article published on 13 April 2021

praja2 regulates KSR1 stability and mitogenic signaling

scientific article published on 19 May 2016

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