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List of works by Juan M Falcón-Pérez

A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients

scientific article published on 5 September 2017

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

scientific article published on 23 December 2016

A Pilot Study on the Potential of RNA-Associated to Urinary Vesicles as a Suitable Non-Invasive Source for Diagnostic Purposes in Bladder Cancer.

scientific article published on 22 January 2014

A fast method for the quantitation of key metabolites of the methionine pathway in liver tissue by high-resolution mass spectrometry and hydrophilic interaction ultra-performance liquid chromatography

scientific article published on 28 March 2013

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

scientific article

Abundance of Cytochromes in Hepatic Extracellular Vesicles Is Altered by Drugs Related With Drug-Induced Liver Injury

scientific article published on 23 August 2018

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

scientific article published on 15 August 2019

BLOC-1 deficiency causes alterations in amino acid profile and in phospholipid and adenosine metabolism in the postnatal mouse hippocampus.

scientific article

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes

scientific journal article

BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules

scientific article

Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4

scientific article

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

scientific article published on 04 January 2021

Cellular uptake of gold nanoparticles bearing HIV gp120 oligomannosides

scientific article

Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes

scientific article published on December 2008

Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6

scientific article

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

scientific article published on 25 June 2018

Comparative miRNA Analysis of Urine Extracellular Vesicles Isolated through Five Different Methods

scientific article published on 10 December 2016

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

scientific article published on 17 January 2018

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

scientific article

Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains

scientific article published on August 2001

EV-Associated miRNAs from Peritoneal Lavage are a Source of Biomarkers in Endometrial Cancer

scientific article published on 18 June 2019

EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer

scientific article published on 21 October 2019

EVpedia: a community web portal for extracellular vesicles research

scientific article

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion

scientific article published on 4 December 2014

Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake

scientific article published on 2 January 2018

Fast characterisation of cell-derived extracellular vesicles by nanoparticles tracking analysis, cryo-electron microscopy, and Raman tweezers microspectroscopy

scientific article

First Symposium of "Grupo Español de Investigación en Vesículas Extracelulares (GEIVEX)", Segovia, 8-9 November 2012.

scientific article

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

scientific article

Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis

scientific article published on 01 August 1999

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives.

scientific article

Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism.

scientific article

Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate

scientific article published on 12 July 2019

Human mammospheres secrete hormone-regulated active extracellular vesicles

scientific article published on 03 January 2014

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles

scientific article published on 17 March 2017

Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

scientific article

Isolation and characterization of exosomes derived from fertile sheep hydatid cysts.

scientific article published on 23 January 2017

Isolation of urinary exosomes from animal models to unravel noninvasive disease biomarkers.

scientific article

Liver extracellular vesicles in health and disease

scientific article published on 11 July 2012

Low-dose statin treatment increases prostate cancer aggressiveness.

scientific article published on 31 October 2017

Meeting report of the European mouse complex genetics network SYSGENET.

scientific article published on 15 May 2013

Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression.

scientific article published on 7 May 2018

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

scientific article published on 26 January 2017

Metabolomics Applied to the Study of Extracellular Vesicles

scientific article published on 12 November 2019

Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee

scientific article published on 25 August 2020

Microarray-Based Identification of Lectins for the Purification of Human Urinary Extracellular Vesicles Directly from Urine Samples

scientific article published on 08 July 2014

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Non-invasive detection of drug toxicity in rats by solid-phase extraction and MALDI-TOF analysis of urine samples.

scientific article

Overview of extracellular microvesicles in drug metabolism.

scientific article published on May 2010

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

scientific article

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

scientific article

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

scientific article published on 18 April 2014

Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma.

scientific article published on 25 April 2018

Role of Aramchol in steatohepatitis and fibrosis in mice.

scientific article published on 4 October 2017

SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

scientific article

Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity

scientific article

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.

scientific article published on 26 May 2017

Sorting signal targeting mRNA into hepatic extracellular vesicles

scientific article

Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria.

scientific article published on January 2011

Sub‐proteome approach to the knowledge of liver ⬇️

scientific article published on 03 February 2010

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.

scientific article

Synthesis, dihydrofolate reductase inhibition, anti-proliferative testing, and saturation transfer difference ¹H-NMR study of some new 2-substituted-4,6-diaminopyrimidine derivatives

scientific article published on January 2012

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

scientific article published on 01 September 2018

Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality

scientific journal article

Tau Overexpression Results in Its Secretion via Membrane Vesicles

scientific article published on 21 January 2012

The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5).

scientific article

The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

scientific article published on 19 August 2018

The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis

scientific article (publication date: April 2002)

Transcriptome of extracellular vesicles released by hepatocytes.

scientific article

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria

scientific article

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.

scientific article

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

scientific article

Virtual expert mass spectrometrist: iTRAQ tool for database-dependent search, quantitation and result storage.

scientific article

Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.

scientific article published in November 2004

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes

scientific article

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.

scientific article published on 28 June 2017

miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments

scientific article

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