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List of works by Frederick E. Domann

2-Deoxyglucose combined with wild-type p53 overexpression enhances cytotoxicity in human prostate cancer cells via oxidative stress.

scientific article published on 28 November 2007

A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.

scientific article

A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability

scientific article

A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency

scientific article published on September 2003

A role for epigenetics in hearing: Establishment and maintenance of auditory specific gene expression patterns.

scientific article

AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma

scientific article published on 26 June 2007

AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes

scientific article

AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells

scientific article

Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma

scientific article published on December 2014

Aberrant Free Radical Biology Is a Unifying Theme in the Etiology and Pathogenesis of Major Human Diseases ⬇️

scientific article published on April 17, 2013

Aberrant Promoter CpG Methylation Is a Mechanism for Impaired PHD3 Expression in a Diverse Set of Malignant Cells ⬇️

scientific article published on January 28, 2011

Absence of manganese superoxide dismutase delays p53-induced tumor formation

scientific article published on 13 January 2014

Acetaldehyde activates Jun/AP-1 expression and DNA binding activity in human oral keratinocytes

scientific article

An epigenetic perspective on the free radical theory of development

scientific article

Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells

scientific article published on April 1994

Apoptosis induced by selenomethionine and methioninase is superoxide mediated and p53 dependent in human prostate cancer cells

scientific article published on December 2006

Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling

scientific article

Celecoxib toxicity is cell cycle phase specific

scientific article published on 01 April 2007

Constitutive AP-1 DNA binding and transactivating ability of malignant but not benign mouse epidermal cells

scientific article published on February 1994

Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides.

scientific article

Corrigendum to "Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest".

scientific article published on 2 February 2015

Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest ⬇️

scientific article published on May 28, 2012

Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation

scientific article

Decreased expression of manganese superoxide dismutase in transformed cells is associated with increased cytosine methylation of the SOD2 gene

scientific article published on August 1999

Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes

scientific article published on 01 September 1999

Differential activation of catalase expression and activity by PPAR agonists: implications for astrocyte protection in anti-glioma therapy.

scientific article published on 26 January 2013

Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip

scientific article

Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells

scientific article published on 18 June 2015

Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth

scientific article published on January 2002

Dual-expressing adenoviral vectors encoding the sodium iodide symporter for use in noninvasive radiological imaging of therapeutic gene transfer.

scientific article published in April 2006

Editorial: maspin as a molecular target for cancer therapy

scientific article

Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells

scientific article published on January 2009

Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge

scientific article

Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126).

scientific article

Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells

scientific article published on 13 September 2006

Epigenetic regulation of maspin expression in human ovarian carcinoma cells

scientific article published on 7 February 2006

Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis ⬇️

scientific article published on January 14, 2013

Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses

scientific article published on 29 January 2014

Expression of AP-2 alpha in SV40 immortalized human lung fibroblasts is associated with a distinct pattern of cytosine methylation in the AP-2 alpha promoter.

scientific article published in May 2001

Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells

scientific article

Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPases

scientific article published on 21 October 2016

Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis.

scientific article published on 7 November 2011

Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS).

scientific article published on March 2004

Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2(-•) and H2O2.

scientific article published on 19 October 2011

Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis.

scientific article published on 17 March 2011

Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe

scientific article

Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines.

scientific article published on 16 December 2013

Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter.

scientific article published in December 2002

Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells

scientific article

Inactivation of primary antioxidant enzymes in mouse keratinocytes by photodynamically generated singlet oxygen.

scientific article published on July 2006

Increased efficacy of in vitro Photofrin photosensitization of human oral squamous cell carcinoma by iron and ascorbate

scientific article published in October 1997

Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).

scientific article published on November 2007

Inhibition of carcinoma formation and of vascular invasion in grafts of radiation-initiated thyroid clonogens by unirradiated thyroid cells

scientific article

Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose.

scientific article published on February 2006

Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase

scientific article published on 01 April 2000

Integrin α3β1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma.

scientific article published on 03 September 2013

Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure

scientific article published in June 2009

Intrinsic radiation resistance in human chondrosarcoma cells

scientific article published on 5 June 2006

Involvement of PKC, p38 MAPK and AP-2 in IL-1beta-induced expression of cyclooxygenase-2 in human pulmonary epithelial cells

scientific article published on January 2006

L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides

scientific article published in September 2003

Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes

scientific article

Locally targeted delivery of a micron-size radiation therapy source using temperature-sensitive hydrogel

scientific article

Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma.

scientific article published on 29 January 2015

Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender

scientific article

Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes.

scientific article

Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells.

scientific article published on 5 December 2012

Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland

scientific article published on 5 September 2012

Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor

scientific article published on December 2005

Metabolic defects provide a spark for the epigenetic switch in cancer

scientific article published on 10 April 2009

Mitochondria, energetics, epigenetics, and cellular responses to stress

scientific article

Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival

scientific article

Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation

scientific article published on December 2009

Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability

scientific article published on August 2006

NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.

scientific article published on 31 July 2013

Noninvasive radiological imaging of pulmonary gene transfer and expression using the human sodium iodide symporter

scientific article

On the cells of origin of radiogenic thyroid cancer: new studies based on an old idea

scientific article published in December 1991

Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion.

scientific article published on 14 July 2009

PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells

scientific article

Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage of photodynamic therapy

scientific article published in April 2001

Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition

scientific article

RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.

scientific article published on December 2006

Rapid and direct quantitative RT-PCR method to measure promoter activity

scientific article published on September 2006

Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase ⬇️

scientific article published on January 1, 2012

Redox Regulation of Adenovirus-Induced AP-1 Activation by Overexpression of Manganese-Containing Superoxide Dismutase ⬇️

scientific article published on January 1, 2002

Redox modulation of AP-2 DNA binding activity in vitro.

scientific article published in August 1998

Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome

scientific article

Regulation of 14-3-3sigma expression in human thyroid carcinoma is epigenetically regulated by aberrant cytosine methylation.

scientific article

Regulation of CuZnSOD and its redox signaling potential: implications for amyotrophic lateral sclerosis

scientific article

Regulation of SOD2 in Cancer by Histone Modifications and CpG Methylation: Closing the Loop Between Redox Biology and Epigenetics ⬇️

scientific article published on October 18, 2012

Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node

scientific article

Restoration of thyroid function after total thyroidectomy and quantitative thyroid cell transplantation

scientific article published on 01 December 1990

Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population

scientific article

Role for DNA methylation in the control of cell type specific maspin expression

scientific article

SIRT6 minor allele genotype is associated with >5-year decrease in lifespan in an aged cohort.

scientific article

SOD2 targeted gene editing by CRISPR/Cas9 yields Human cells devoid of MnSOD.

scientific article published on 21 July 2015

SSRI use and clinical outcomes in epithelial ovarian cancer.

scientific article published on 21 April 2016

Sensitivity to Low-Dose/Low-LET Ionizing Radiation in Mammalian Cells Harboring Mutations in Succinate Dehydrogenase Subunit C is Governed by Mitochondria-Derived Reactive Oxygen Species ⬇️

scientific article published on November 17, 2010

Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes.

scientific article published on 23 November 2014

Superoxide signaling mediates N-acetyl-L-cysteine-induced G1 arrest: regulatory role of cyclin D1 and manganese superoxide dismutase

scientific article published on July 2007

TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis

scientific article

The redox basis of epigenetic modifications: from mechanisms to functional consequences.

scientific article

The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis.

scientific article

The use of RT-PCR to distinguish between plasmid MnSOD transcripts and endogenous MnSOD mRNA.

scientific article published on November 1995

Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia.

scientific article published on 17 May 2005

Transcription factor AP-2 mRNA and DNA binding activity are constitutively expressed in SV40-immortalized but not normal human lung fibroblasts

scientific article published on 01 April 1999

Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5' CpG island

scientific article published in January 1997

Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.

scientific article

Transgenic biosynthesis of trypanothione protects Escherichia coli from radiation-induced toxicity.

scientific article published on September 2010

V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymes

scientific article

ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells

scientific article

v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-kappaB.

scientific article published on August 2001

v-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species

scientific article published on April 2002

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