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List of works by Nicola Marchi

A dynamic in vitro BBB model for the study of immune cell trafficking into the central nervous system

scientific article

A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity

scientific article published on 28 May 2019

A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine

scientific article

A pro-convulsive carbamazepine metabolite: quinolinic acid in drug resistant epileptic human brain

scientific article published on 09 March 2012

A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches.

scientific article published on September 2013

Antagonism of peripheral inflammation reduces the severity of status epilepticus.

scientific article

Blood-Brain Barrier Damage Induces Release of α2-Macroglobulin ⬇️

scientific article published on April 24, 2003

Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases.

scientific article published on October 2011

Blood-brain barrier damage and brain penetration of antiepileptic drugs: role of serum proteins and brain edema

scientific article

Blood-brain barrier damage, but not parenchymal white blood cells, is a hallmark of seizure activity

scientific article

Blood-brain barrier, bulk flow, and interstitial clearance in epilepsy

scientific article

Blood–brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches ⬇️

scientific article published on August 20, 2012

Cellular localization and functional significance of CYP3A4 in the human epileptic brain.

scientific article

Central nervous system lymphatic unit, immunity, and epilepsy: Is there a link?

scientific article published on 14 February 2019

Cerebrovascular heterogeneity and neuronal excitability.

scientific article

Cerebrovascular pathology during the progression of experimental Alzheimer's disease

scientific article published on 7 January 2016

Cerebrovascular remodeling and epilepsy

scientific article published on 16 October 2012

Combined effects of prenatal inhibition of vasculogenesis and neurogenesis on rat brain development

scientific article published on 30 September 2008

Competitive apnea and its effect on the human brain: focus on the redox-regulation of blood-brain barrier permeability and neuronal-parenchymal integrity

scientific article published on 30 November 2017

Consequences of repeated blood-brain barrier disruption in football players

scientific article published in 2013

Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development

scientific article published on 5 October 2006

Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs

scientific article

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

scientific article published on 27 December 2019

Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression

scientific article

Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice

scientific article

HIV Neuroinfection and Alzheimer's Disease: Similarities and Potential Links?

article

Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures.

scientific article published on 10 November 2017

High-speed optical mapping of heart and brain voltage activities in zebrafish larvae exposed to environmental contaminants

scientific article published in 2023

IFN-γ, IL-17A, or zonulin rapidly increase the permeability of the blood-brain and small intestinal epithelial barriers: Relevance for neuro-inflammatory diseases

scientific article published on 16 November 2018

Improving the clinical management of traumatic brain injury through the pharmacokinetic modeling of peripheral blood biomarkers

scientific article

In vitro responsiveness of human-drug-resistant tissue to antiepileptic drugs: insights into the mechanisms of pharmacoresistance

scientific article

In vivo and in vitro effects of pilocarpine: relevance to ictogenesis.

scientific article published on 20 July 2007

Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release

scientific article published in July 2008

Inflammatory pathways of seizure disorders

scientific article published on 16 December 2013

Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

scientific article published in April 2006

Is peripheral immunity regulated by blood-brain barrier permeability changes?

scientific article

Lack of CAR impacts neuronal function and cerebrovascular integrity in vivo.

scientific article published on 27 May 2016

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases.

scientific article published on 6 December 2016

Management of the patient with medically refractory epilepsy.

scientific article published on December 2009

Modulation of glucocorticoid receptor in human epileptic endothelial cells impacts drug biotransformation in an in vitro blood-brain barrier model

scientific article published on 28 September 2018

Modulation of peripheral cytotoxic cells and ictogenesis in a model of seizures.

scientific article published on 31 May 2011

Multimodal investigations of trans-endothelial cell trafficking under condition of disrupted blood-brain barrier integrity

scientific article

Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents ⬇️

scientific article published on December 8, 2011

Neurovascular Drug Biotransformation Machinery in Focal Human Epilepsies: Brain CYP3A4 Correlates with Seizure Frequency and Antiepileptic Drug Therapy

scientific article published on 26 June 2019

Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells.

scientific article published on 15 February 2017

PDGFRβ(+) cells in human and experimental neuro-vascular dysplasia and seizures

scientific article published on 14 August 2015

Pathophysiological implications of neurovascular P450 in brain disorders

scientific article

Pattern of P450 expression at the human blood-brain barrier: roles of epileptic condition and laminar flow

scientific article

Peripheral detection of S100beta during cardiothoracic surgery: what are we really measuring?

scientific article published in July 2004

Peripheral markers of blood-brain barrier damage.

scientific article

Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity.

scientific article published on 22 July 2017

Prenatal exposure to thalidomide, altered vasculogenesis, and CNS malformations

scientific article published on 20 July 2006

ProApolipoprotein A1: a serum marker of brain metastases in lung cancer patients

scientific article

Redistribution of PDGFRβ cells and NG2DsRed pericytes at the cerebrovasculature after status epilepticus

scientific article

Robust and Gradient Thickness Porous Membranes for In Vitro Modeling of Physiological Barriers

scientific article published on 9 November 2020

S100beta as a predictor of brain metastases: brain versus cerebrovascular damage

scientific article published in August 2005

SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease

scientific article published on 18 October 2014

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature

scientific article published on 9 February 2018

Seizure-promoting effect of blood-brain barrier disruption

scientific article

Selective and persistent upregulation of mdr1b mRNA and P-glycoprotein in the parahippocampal cortex of chronic epileptic rats

scientific article

Serum S100B: a potential biomarker for suicidality in adolescents?

scientific article (publication date: 14 June 2010)

Serum S100beta: a noninvasive marker of blood-brain barrier function and brain lesions

scientific article

Significance of MDR1 and multiple drug resistance in refractory human epileptic brain

scientific article

Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits

scientific article

Small vessel ischemic disease of the brain and brain metastases in lung cancer patients

scientific article

The blood-brain barrier hypothesis in drug resistant epilepsy

scientific article published on 16 January 2012

The etiological role of blood-brain barrier dysfunction in seizure disorders

scientific article published on 30 March 2011

The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures

scientific article published on 30 April 2019

The pericyte-glia interface at the blood-brain barrier.

scientific article published on 8 February 2018

The role of shear stress in Blood-Brain Barrier endothelial physiology

scientific article

Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions

scientific article published in April 2018

Transporters in drug-refractory epilepsy: clinical significance.

scientific article published on January 2010

Vascular and Parenchymal Mechanisms in Multiple Drug Resistance: a Lesson from Human Epilepsy ⬇️

scientific article published on May 1, 2003

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