List of works by Thomas Hoenen

A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

scientific article

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

scientific article published on 07 August 2018

A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals

scientific article published on 07 June 2013

A novel life cycle modeling system for Ebola virus shows a genome length-dependent role of VP24 in virus infectivity

scientific article

An Improved Reverse Genetics System to Overcome Cell-Type-Dependent Ebola Virus Genome Plasticity

scientific article

An upstream open reading frame modulates ebola virus polymerase translation and virus replication

scientific article

Analysis of the highly diverse gene borders in Ebola virus reveals a distinct mechanism of transcriptional regulation

scientific article

Assessing the contribution of interferon antagonism to the virulence of West African Ebola viruses

scientific article published on 5 August 2015

Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription

scientific article

Characterization of the catalytic center of the Ebola virus L polymerase

scientific article published on 9 October 2017

Clinical Chemistry of Patients With Ebola in Monrovia, Liberia

scientific article published on 28 July 2016

Clomiphene and Its Isomers Block Ebola Virus Particle Entry and Infection with Similar Potency: Potential Therapeutic Implications

scientific article

Complete genome sequences of three ebola virus isolates from the 2014 outbreak in west Africa

scientific article

Cryoelectron microscopic structure of the nucleoprotein–RNA complex of the European filovirus, Lloviu virus

Current ebola vaccines

scientific article

Detection of Viral RNA in Tissues following Plasma Clearance from an Ebola Virus Infected Patient

scientific article

Development and application of reporter-expressing mononegaviruses: current challenges and perspectives

scientific article published on 23 January 2014

Differences in Viral RNA Synthesis but Not Budding or Entry Contribute to the In Vitro Attenuation of Reston Virus Compared to Ebola Virus

scientific article published on 11 August 2020

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure

scientific article (publication date: 2013)

Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis

scientific article

Ebola virus inclusion body formation and RNA synthesis are controlled by a novel domain of NP interacting with VP35

scientific article published on 03 June 2020

Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes

scientific article

Ebola virus: unravelling pathogenesis to combat a deadly disease

scientific article

Ebolavirus in West Africa, and the use of experimental therapies or vaccines

scientific article

Efficient budding of the tacaribe virus matrix protein z requires the nucleoprotein

scientific article published on 27 January 2010

Establishment and application of an infectious virus-like particle system for Marburg virus

scientific article published on 13 January 2010

Evolution and Antiviral Specificities of Interferon-Induced Mx Proteins of Bats against Ebola, Influenza, and Other RNA Viruses.

scientific article published on 10 May 2017

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

scientific article published on 26 September 2014

Filovirus proteins for antiviral drug discovery: A structure/function analysis of surface glycoproteins and virus entry

scientific article

Generation and Optimization of a Green Fluorescent Protein-Expressing Transcription and Replication-Competent Virus-Like Particle System for Ebola Virus

scientific article published on 01 November 2018

Genus-specific recruitment of filovirus ribonucleoprotein complexes into budding particles

scientific article

Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice

scientific article

In vitro evaluation of antisense RNA efficacy against filovirus infection, by use of reverse genetics

scientific article published on November 2007

Inclusion bodies are a site of ebolavirus replication

scientific article

Infection of naive target cells with virus-like particles: implications for the function of ebola virus VP24.

scientific article

Lifecycle modelling systems support inosine monophosphate dehydrogenase (IMPDH) as a pro-viral factor and antiviral target for New World arenaviruses

scientific article

Minigenomes, transcription and replication competent virus-like particles and beyond: reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses

scientific article published on 14 June 2011

Modeling the lifecycle of Ebola virus under biosafety level 2 conditions with virus-like particles containing tetracistronic minigenomes

scientific article published on 27 September 2014

Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

scientific article

Oligomerization of Ebola virus VP40 is essential for particle morphogenesis and regulation of viral transcription

scientific article

Phosphorylation of Ebola virus VP30 influences the composition of the viral nucleocapsid complex: impact on viral transcription and replication

scientific article

Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients

scientific article published on 15 August 2016

Response to Comment on "Mutation rate and genotype variation of Ebola virus from Mali case sequences".

scientific article published on 11 August 2016

Reverse genetics systems as tools for the development of novel therapies against filoviruses

scientific article

Sequencing of Ebola Virus Genomes Using Nanopore Technology

scientific article

Serological Evidence for the Circulation of Ebolaviruses in Pigs From Sierra Leone

scientific article published on 01 November 2018

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

scientific article

TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction

scientific article published on 09 May 2022

Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages

scientific article

Tetherin inhibits Nipah virus but not Ebola virus replication in fruit bat cells

scientific article published on 17 January 2019

The Cellular Protein CAD is Recruited into Ebola Virus Inclusion Bodies by the Nucleoprotein NP to Facilitate Genome Replication and Transcription

scientific article published on 01 May 2020

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression

scientific article published on 11 January 2020

The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo

scientific article published in 2012

The Ebola virus ribonucleoprotein complex: a novel VP30-L interaction identified

scientific article

The Merits of Malaria Diagnostics during an Ebola Virus Disease Outbreak

scientific article published on February 2016

The role of oligomerization for the biological functions of the arenavirus nucleoprotein

scientific article published on 4 April 2013

Therapeutic strategies to target the Ebola virus life cycle

scientific article published on 24 July 2019

VP40 octamers are essential for Ebola virus replication.

scientific article

Virology. Mutation rate and genotype variation of Ebola virus from Mali case sequences

scientific article

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

scientific article published on 5 November 2013

iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility

scientific article published on 06 April 2021

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