Search filters

List of works by Kazumitsu Ueda

24(S)-hydroxycholesterol is actively eliminated from neuronal cells by ABCA1.

scientific article published on 8 May 2013

3,3′,4,4′,5-Pentachlorobiphenyl Inhibits Drug Efflux Through P-Glycoprotein in KB-3 Cells Expressing Mutant Human P-Glycoprotein

scientific article

A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.

scientific article published on 9 January 2017

A T3587G germ-line mutation of the MDR1 gene encodes a nonfunctional P-glycoprotein.

scientific article published on April 2006

A chemical probe that labels human pluripotent stem cells

scientific article

A new procedure for determining thymine residues in DNA sequencing. Photoinduced cleavage of DNA fragments in the presence of spermine.

scientific article published on March 1984

A novel missense mutation of ABCA1 in transmembrane alpha-helix in a Japanese patient with Tangier disease.

scientific article

ABC Proteins Protect the Human Body and Maintain Optimal Health

scientific article published on 07 March 2011

ABC Proteins in Evolution

scientific article published on 01 October 2020

ABC proteins involved in lipid homeostasis

scientific article

ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging.

scientific article

ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane

scientific article

ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking

scientific article published on 08 December 2020

ABCB1/MDR1/P-gp employs an ATP-dependent twist-and-squeeze mechanism to export hydrophobic drugs

scientific article published on 04 December 2020

ABCB4 exports phosphatidylcholine in a sphingomyelin-dependent manner

scientific article

ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production.

scientific article

ATP binding properties of the nucleotide-binding folds of SUR1.

scientific article

ATP hydrolysis-dependent conformational changes in the extracellular domain of ABCA1 are associated with apoA-I binding

scientific article published on 25 October 2011

ATP hydrolysis-dependent multidrug efflux transporter: MDR1/P-glycoprotein.

scientific article published on February 2004

ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier.

scientific article published on 8 December 2007

ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion.

scientific article

ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin

scientific article published on 19 November 2012

ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1.

scientific article published on 7 January 2013

Abl kinase interacts with and phosphorylates vinexin

scientific article

Alteration of Substrate Specificity by Mutations at the His61Position in Predicted Transmembrane Domain 1 of Human MDR1/P-Glycoprotein†

scientific article published on 01 July 1997

Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity

scientific article published on 01 August 1997

An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin

scientific article published on 21 January 2019

Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP).

scientific article published on January 1997

Apolipoprotein A-I directly interacts with extracellular domain 1 of human ABCA1

scientific article published on 20 November 2018

Application of vanadate-induced nucleotide trapping to plant cells for detection of ABC proteins.

scientific article

Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins

scientific article published on 01 December 1996

Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4

scientific article

C-terminal of ABCA1 separately regulates cholesterol floppase activity and cholesterol efflux activity

scientific article published on 09 December 2019

Celebrating Dr. Satoshi Ōmura, the recipient of the 2015 Nobel Prize in Physiology or Medicine

scientific article

Cell migration is negatively modulated by ABCA1

scientific article published on 16 November 2018

Cepharanthin, a multidrug resistant modifier, is a substrate for P-glycoprotein.

scientific article

Changes in the asymmetric distribution of cholesterol in the plasma membrane influence streptolysin O pore formation

scientific article published on 14 March 2019

Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency.

scientific article

Characterization of Coptis japonica CjABCB2, an ATP-binding cassette protein involved in alkaloid transport.

scientific article published on 10 March 2012

Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein

scientific article published in September 2002

Cholesterol and plant sterol efflux from cultured intestinal epithelial cells is mediated by ATP-binding cassette transporters

scientific article published on 7 August 2007

Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism

scientific journal article

Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo

scientific article published on 31 March 2010

Cyclosporine A and PSC833 inhibit ABCA1 function via direct binding

scientific article

DNA damage caused by ascorbate in the presence of Cu2+ induces mutations

scientific article

DNA damage induced by ascorbate in the presence of Cu2+.

scientific article published in January 1988

Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum

scientific article

Deleting two C-terminal alpha-helices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMP-PNP.

scientific article published on 12 February 2010

Deletion and insertion mutants of the multidrug transporter.

scientific article published in August 1989

Detection of ABCA7-positive cells in salivary glands from patients with Sjögren's syndrome

scientific article published on October 2005

Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay

scientific article published in November 1989

Different Binding Properties and Affinities for ATP and ADP among Sulfonylurea Receptor Subtypes, SUR1, SUR2A, and SUR2B

scientific article published in Journal of Biological Chemistry

Different drug sensitivity in two neuroblastoma cell lines established from the same patient before and after chemotherapy

scientific article published on March 1991

Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney

scientific article published on September 1993

Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATP

scientific article published in Journal of Biological Chemistry

Direct detection of ABCA1-dependent HDL formation based on lipidation-induced hydrophobicity change in apoA-I

scientific article

Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex

scientific article published on 27 May 2012

Direct interaction of nuclear liver X receptor-beta with ABCA1 modulates cholesterol efflux

scientific article published on 9 September 2008

Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide

scientific article published in June 2000

Dlg5 interacts with the TGF-β receptor and promotes its degradation

scientific article

Dominant expression of ATP-binding cassette transporter-1 on basolateral surface of Caco-2 cells stimulated by LXR/RXR ligands.

scientific article

Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein

scientific article

Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A

scientific article

Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein

scientific article published on July 1996

Effects of Ala Substitution for Conserved Cys Residues in Mouse Ileal and Hepatic Na+-Dependent Bile Acid Transporters

scientific article published on 07 August 2007

Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis

scientific article

Enhanced apoA-I-dependent cholesterol efflux by ABCA1 from sphingomyelin-deficient Chinese hamster ovary cells

scientific article published on 3 April 2007

Enzymatic measurement of phosphatidic acid in cultured cells

scientific article published on 15 April 2009

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

scientific article

Expression of a human complementary DNA for the multidrug resistance gene in murine hematopoietic precursor cells with the use of retroviral gene transfer.

scholarly article

Expression of the multidrug resistance, MDR1, gene in neuroblastomas

scientific article published on January 1990

Expression of vinexin alpha in the dorsal half of the eye and in the cardiac outflow tract and atrioventricular canal.

scientific article

Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin

scientific article

Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe

scientific article

Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1.

scientific article

Formation of two intramolecular disulfide bonds is necessary for ApoA-I-dependent cholesterol efflux mediated by ABCA1.

scientific article published on 3 March 2009

Function and regulation of ABCA1--membrane meso-domain organization and reorganization

scientific article published on 13 June 2011

Functional Analysis of a Mutant Sulfonylurea Receptor, SUR1-R1420C, That Is Responsible for Persistent Hyperinsulinemic Hypoglycemia of Infancy

scientific article published in Journal of Biological Chemistry

Functional expression of human P-glycoprotein in Schizosaccharomyces pombe.

scientific article

Functional role of the linker region in purified human P-glycoprotein.

scientific article published on 21 May 2009

Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins

scientific article published on January 1990

Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1).

scientific article published on April 1992

Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.

scientific article

Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation.

scientific article published in June 2006

Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles.

scientific article

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein

scientific article

Human MDR1 and MRP1 recognize berberine as their transport substrate

scientific article published on 7 January 2007

Human P-glycoprotein as a multi-drug transporter analyzed by using transepithelial transport system.

scientific article published on January 1994

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone

scientific article published on December 1992

Human P-glycoprotein transports cyclosporin A and FK506.

scientific article published on March 1993

Improved expression and purification of human multidrug resistance protein MDR1 from baculovirus-infected insect cells.

scientific article

In situ localization of the human multidrug-resistance gene mRNA using thymine-thymine dimerized single-stranded cDNA.

scientific article

In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines

scientific article published on 16 March 2016

Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact

scientific article

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

scientific article

Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica.

scholarly article

Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins

scientific journal article

Involvement of phosphatases in the anchorage-dependent regulation of ERK2 activation

scientific article published on 12 March 2007

Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.

scientific article published in December 1987

KATP channel interaction with adenine nucleotides.

scientific article

Leishmania LABCG2 transporter is involved in ATP-dependent transport of thiols

scientific article

Lipid outward translocation by ABC proteins

scientific article published on 20 April 2010

Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation

scientific article published on 20 April 2011

Loss of Dlg5 expression promotes the migration and invasion of prostate cancer cells via Girdin phosphorylation

scientific article published on 24 March 2014

Lysine residues of ABCA1 are required for the interaction with apoA-I.

scientific article published in July 2011

Lysophosphatidylcholine export by human ABCA7.

scientific article published on 31 March 2017

MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.

scientific article

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

scientific article published on January 1992

Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol

scientific article published on January 2007

Molecular biology of drug resistance

scientific article published on January 1987

Molecular mechanisms of subcellular localization of ABCG5 and ABCG8.

scientific article published on 7 March 2009

Mutational analysis of uncharged polar residues and proline in the distal one-third (Thr130-Pro142) of the highly conserved region of mouse Slc10a2.

scientific article

Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding

scientific article

Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells

scientific article

Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein

scientific article published on 01 August 1998

Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol

scientific article published on 26 December 2016

P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance

scientific article

P-glycoprotein-mediated transcellular transport of MDR-reversing agents

scientific article

P-glycoprotein. ATP hydrolysis by the N-terminal nucleotide-binding domain

scientific article published on March 1992

Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells

scientific article published on 10 July 2006

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

scientific article published on 14 October 2013

Position 834 in TM6 plays an important role in cholesterol and phosphatidylcholine transport by ABCA1.

scientific article published on 12 January 2015

Posttranscriptional regulation of human ABCA7 and its function for the apoA-I-dependent lipid release

scientific journal article

Production of a site specifically cleavable P-glycoprotein-beta-galactosidase fusion protein

scientific article published on 01 April 1991

Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin

scientific article

Purification and ATPase activity of human ABCA1.

scientific article published on 24 February 2006

Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1 ) expression caused by arsenite

article

Recent progress in P-glycoprotein research.

scientific article

Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

scientific article published on March 1997

Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation.

scientific article published on 6 January 2008

Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.

scientific article published in January 2003

Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells

scientific article

Role of interaction with vinculin in recruitment of vinexins to focal adhesions

scientific article published in October 2005

Selective Elimination of Human Pluripotent Stem Cells by a Marine Natural Product Derivative

scientific article published on 03 July 2014

Sequence specific damage of DNA induced by reducing sugars

scientific article published on January 1985

Sequence-specific DNA damage induced by reduced mitomycin C and 7-N-(p-hydroxyphenyl)mitomycin C

scientific article published on September 1984

Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner

scientific article published on 10 April 2006

Small-molecule-induced clustering of heparan sulfate promotes cell adhesion.

scientific article published on 17 July 2013

Sodium taurocholate-dependent lipid efflux by ABCA1: effects of W590S mutation on lipid translocation and apolipoprotein A-I dissociation

scientific article

Specific drug binding by purified lipid-reconstituted P-glycoprotein: dependence on the lipid composition

scientific article published on June 1992

Sphingomyelin-dependence of cholesterol efflux mediated by ABCG1.

scientific article published on 29 August 2007

Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog

scientific article

Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport.

scientific article published on 20 May 2016

Structures and functions of xenobiotic efflux pump P-glycoprotein and MRP--important molecular targets for cancer chemotherapy

scientific article published on December 1, 1997

Successful utilization of coronary covered stents to treat a common hepatic artery pseudoaneurysm secondary to pancreatic fistula after Whipple's procedure: report of a case.

scientific article

Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation.

scientific article published on 18 April 2018

The ABCA1 Q597R mutant undergoes trafficking from the ER upon ER stress

scientific article

The COP9 signalosome controls ubiquitinylation of ABCA1.

scientific article published on 4 March 2009

The distribution of vinculin to lipid rafts plays an important role in sensing stiffness of extracellular matrix.

scientific article

The effects of metal ions on the DNA damage induced by hydrogen peroxide

scientific article published in January 1990

The effects of neurological disorder-related codon variations of ABCA13 on the function of the ABC protein

scientific article published on 7 December 2012

The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.

scientific article

The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

article

The role of the interaction of the vinculin proline-rich linker region with vinexin α in sensing the stiffness of the extracellular matrix.

scientific article published on 19 February 2014

Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome

scientific article published in November 2002

Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants.

scientific article

Transepithelial transport and cellular accumulation of steroid hormones and polychlorobiphenyl in porcine kidney cells expressed with human P-glycoprotein

scientific article

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

scientific article published on November 1992

Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin

scientific article

Use of recombinant P-glycoprotein fragments to produce antibodies to the multidrug transporter

scientific article published in January 1990

Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism

scientific article published on 15 January 2004

Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.

scientific article

Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes

scientific article published on 23 January 2017

Vinexin beta regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor.

scientific article

Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells

scientific article published in Scientific Reports

Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities.

scientific article

Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction

scientific article (publication date: February 2002)

WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions.

scientific article

[ABC proteins move lipids]

scientific article published on 01 April 2006

[Molecular mechanisms for drug transport by MDR1/P-glycoprotein]

scientific article published on 01 June 1997

[Multidrug resistance of cancer cells mediated by ABC superfamily transporters]

scientific article published on 01 May 1997

[The multidrug-resistance gene MDR1].

scientific article published in October 1988

v-Src-mediated transformation suppresses the expression of focal adhesion protein vinexin

scientific article published on 12 February 2009