Search filters

List of works by Jeremy Chien

A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer

scientific article (publication date: 26 February 2004)

A large-scale comparative study of isoform expressions measured on four platforms

scientific article published on 30 March 2020

A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation

scientific article

A targeted genetic association study of epithelial ovarian cancer susceptibility

scientific article published on February 2016

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration

scientific article

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

scientific article published on 23 October 2013

Analysis of gene expression in stage I serous tumors identifies critical pathways altered in ovarian cancer

scientific article published in May 2009

Assessment of hepatocyte growth factor in ovarian cancer mortality

scientific article

Assessment of resistance to anoikis in ovarian cancer

scientific article published on January 2013

Bevacizumab May Differentially Improve Ovarian Cancer Outcome in Patients with Proliferative and Mesenchymal Molecular Subtypes.

scientific article

Calcitonin inhibits anterior pituitary cell proliferation in the adult female rats

scientific article published in September 1999

Calcitonin is a prostate epithelium-derived growth stimulatory peptide

scientific article published on July 2001

Calcitonin is expressed in gonadotropes of the anterior pituitary gland: its possible role in paracrine regulation of lactotrope function

scientific article

Challenges and opportunities for next-generation sequencing in companion diagnostics

scientific article published on 24 September 2014

Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells.

scientific article published on 11 July 2016

Cisplatin and Pemetrexed Activate AXL and AXL Inhibitor BGB324 Enhances Mesothelioma Cell Death from Chemotherapy.

scientific article published in January 2017

Clinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C status

scientific article

Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors

scientific article

Coiled-Coil and C2 Domain-Containing Protein 1A (CC2D1A) Promotes Chemotherapy Resistance in Ovarian Cancer

scientific article published on 01 October 2019

Comparison of gene expression patterns between avian and human ovarian cancers

article

Complete Transcriptome RNA-Seq

scientific article

Constitutive activation of stimulatory guanine nucleotide binding protein (G(S)alphaQL)-mediated signaling increases invasiveness and tumorigenicity of PC-3M prostate cancer cells

scientific article published on 01 June 1999

Downregulation of HtrA1 promotes resistance to anoikis and peritoneal dissemination of ovarian cancer cells

scientific article published on 13 April 2010

Effect of the p53 P72R Polymorphism on Mutant TP53 Allele Selection in Human Cancer

scientific article published on 01 September 2021

Elevated expression of serine protease HtrA1 in preeclampsia and its role in trophoblast cell migration and invasion

scientific article published on 29 July 2008

Emerging Cancer Therapeutic Targets in Protein Homeostasis

scientific article published on 27 August 2018

Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.

scientific article published on 19 February 2007

Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer.

scientific article

Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel

scientific article published on 09 April 2013

Expression and functional significance of HtrA1 loss in endometrial cancer

scientific article

Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion

scientific article

FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq.

scientific article

Genetic Evidence for Early Peritoneal Spreading in Pelvic High-Grade Serous Cancer.

scientific article published on 7 March 2018

Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity

scientific article published on 09 September 2019

HSulf-1 inhibits angiogenesis and tumorigenesis in vivo

scientific article

HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells

scientific article

HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma.

scientific article

Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance

scientific article published on August 2005

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors

scientific article published on 29 July 2019

High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines

scientific article

Highly parallel genome-wide expression analysis of single mammalian cells

scientific article (publication date: 2012)

HtrA serine proteases as potential therapeutic targets in cancer

scientific article published on June 2009

HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation.

scientific article

Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening

scientific article

In vivo modeling of metastatic human high-grade serous ovarian cancer in mice

scientific article published on 04 June 2020

Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer

scientific article published on 30 January 2014

Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.

scientific article published on 15 March 2007

Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer

scientific article

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

scientific article

Meeting Report From the 2016 11th Biennial Ovarian Cancer Research Symposium: Mechanisms of Initiation and Progression of Ovarian Cancers

scientific article published in November 2017

Metformin intake is associated with better survival in ovarian cancer: a case-control study

scientific article published on 3 December 2012

Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.

scientific article published on 17 May 2016

Minichromosome maintenance protein 7 as a potential prognostic factor for progression-free survival in high-grade serous carcinomas of the ovary.

scientific article

Molecular pathogenesis and therapeutic targets in epithelial ovarian cancer.

scientific article published on December 2007

Neonatal Progesterone Programs Adult Uterine Responses to Progesterone and Susceptibility to Uterine Dysfunction

scientific article

Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis ⬇️

scientific article published on 23 December 2015

Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment

scientific article

Olaparib-induced Adaptive Response is Disrupted by FOXM1 Targeting which Enhances Sensitivity to PARP Inhibition.

scientific article published on 15 March 2018

Ovarian Cancer Prevention, Screening, and Early Detection: Report From the 11th Biennial Ovarian Cancer Research Symposium.

scientific article published in November 2017

Piroxicam and cisplatin in a mouse model of peritoneal mesothelioma

scientific article published on October 2006

Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment.

scientific article published on 24 September 2013

Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer

scientific article published on 6 February 2018

Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway

scientific article published on 01 September 2016

Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples.

scientific article published on 23 July 2015

Serine protease HtrA1 associates with microtubules and inhibits cell migration

scientific article published on 26 May 2009

Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

scientific article

Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma

scientific article published on 03 April 2020

Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case.

scientific article published on 10 November 2015

Specific mutations in the D1-D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors

scientific article

Summary of the 2015 American Association for Cancer Research (AACR) Annual Meeting

scientific article published in July 2015

TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway

scientific article

TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer

scientific article

Targeted or whole genome sequencing of formalin fixed tissue samples: potential applications in cancer genomics

scientific article published on 31 July 2015

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

scientific article

The P72R Polymorphism in R248Q/W p53 Mutants Modifies the Mutant Effect on Epithelial to Mesenchymal Transition Phenotype and Cell Invasion via CXCL1 Expression

scientific article published on 28 October 2020

The degree of intratumor mutational heterogeneity varies by primary tumor sub-site.

scientific article published on 28 March 2016

The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer

scientific article

The serine protease HtrA1 is a novel prognostic factor for human mesothelioma

scientific article

Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers

scientific article published on 30 October 2018

Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer

scientific article (publication date: June 2014)

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal

scientific article published on 28 September 2016

VaDiR: an integrated approach to Variant Detection in RNA.

scientific article published on 18 December 2017

WT1 as a Substrate of HtrA2: A Potential Pathway for Therapeutic Targeting by HtrA Proteases ⬇️

scientific article published on August 1, 2010

digit-a tool for detection and identification of genomic interchromosomal translocations

scientific article

hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling.

scientific article

Paulina is supported by:

About Paulina

Help