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List of works by Terence W Spithill

A bicistronic DNA vaccine containing apical membrane antigen 1 and merozoite surface protein 4/5 can prime humoral and cellular immune responses and partially protect mice against virulent Plasmodium chabaudi adami DS malaria.

scientific article published on October 2004

A family of heat shock protein 70-related genes are expressed in the promastigotes of Leishmania major

scientific article published on July 1989

A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation.

scientific article published on 4 June 2010

A novel member of the NK-lysin protein family is developmentally regulated and secreted by Fasciola hepatica.

scientific article published in February 2000

A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications

scientific article published in 2011

Acquisition of resistance against Fasciola gigantica by Indonesian thin tail sheep.

scientific article

Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles

scientific article published on 16 December 2010

Altered mitochondrial ribosomes in a cold-sensitive mutant of Saccharomyces cerevisiae

scientific article published on June 1978

An antigenically distinct lipophosphoglycan on amastigotes of Leishmania major

scientific article published on 01 April 1991

Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference

article

Antibody-dependent cell-mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates

scientific article published on 01 September 2001

Attempted immunisation of sheep against Fasciola hepatica using gamma-irradiated metacercariae

scientific article published on 01 July 1995

Biochemical analysis of recombinant glutathione S-transferase of Fasciola hepatica

scientific article published on 01 February 1995

Biochemical and molecular characterization of Leishmania pifanoi amastigotes in continuous axenic culture

scientific article published on 01 November 1991

Biogenesis of mitochondria 48: mikamycin resistance in Saccharomyces cerevisiae--a mitochondrial mutation conferring resistance to an antimycin A-like contaminant in mikamycin

scientific article published on March 1977

Biogenesis of mitochondria 51: biochemical characterization of a mitochondrial mutation in Saccharomyces cerevisiae affecting the mitochondrial ribosome by conferring resistance to aminoglycoside antibiotics

scientific article published on June 1979

Biogenesis of mitochondria. The effects of altered membrane lipid composition on cation transport by mitochondria of Saccharomyces cerevisiae

scientific article published on August 1973

Cathepsin B proteases of flukes: the key to facilitating parasite control?

scientific article published on 30 June 2010

Characterisation of a novel Kunitz-type molecule from the trematode Fasciola hepatica

scientific article published on 01 October 1995

Characterisation of humoral immune responses in dogs vaccinated with irradiated Ancylostoma caninum.

scientific article

Characterization of integral membrane proteins of Leishmania major by Triton X-114 fractionation and analysis of vaccination effects in mice

scientific article

Characterization of isolates and clones of Leishmania by analysis of kinetoplast DNA

scientific article published on 01 January 1984

Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

scientific article

Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.

scientific article

Comparative kinetics of serological and coproantigen ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with triclabendazole.

scientific article published on 16 April 2013

Confirmation of Fasciola hepatica resistant to triclabendazole in naturally infected Australian beef and dairy cattle

scientific article published on 11 December 2013

Confronting parasites from Canada

scientific article published on 01 December 2002

Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase

scientific article

DNA vaccines and their application against parasites--promise, limitations and potential solutions.

scientific article published in January 2004

DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy

scientific article published on 06 September 2005

Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters.

scientific article

Editorial – ICOPA down under

scientific article published in August 2010

Evaluation of antigens of Fasciola gigantica as vaccines against tropical fasciolosis in cattle.

scientific article published in November 1997

Evidence for high genetic diversity of NAD1 and COX1 mitochondrial haplotypes among triclabendazole resistant and susceptible populations and field isolates of Fasciola hepatica (liver fluke) in Australia.

scientific article published on December 2013

Examination of variables in the vaccination of mice against cutaneous leishmaniasis using living avirulent cloned lines and killed promastigotes of Leishmania major

article by G F Mitchell et al published 1 December 1985 in International Journal for Parasitology

Exploring the Fasciola hepatica tegument proteome

scientific article published on 5 October 2011

Fasciola hepatica and Fasciola gigantica: cloning and characterisation of 70 kDa heat-shock proteins reveals variation in HSP70 gene expression between parasite species recovered from sheep.

scientific article

Fasciola hepatica cathepsin L suppresses sheep lymphocyte proliferation in vitro and modulates surface CD4 expression on human and ovine T cells

scientific article published in February 2002

Fasciola hepatica: Characterization and Cloning of the Major Cathepsin B Protease Secreted by Newly Excysted Juvenile Liver Fluke ⬇️

scientific article published on February 1, 1998

Fasciola hepatica: irradiation-induced alterations in carbohydrate and cathepsin-B protease expression in newly excysted juvenile liver fluke

scientific article published on 01 July 1996

Fasciola hepatica: localisation of glutathione S-transferase isoenzymes in adult and juvenile liver fluke

scientific article published on 01 August 1995

Fasciola hepatica: stage-specific expression of novel gene sequences as identified by differential display.

scientific article published in June 1998

Fasciola: kinetics and quality of humoral responses to fatty acid binding protein and cathepsin l following delivery as DNA vaccines in mice

scientific article published in March 2001

First insight into CD59-like molecules of adult Fasciola hepatica

scientific article published on 21 June 2014

Genomic organization, chromosomal location and transcription of dispersed and repeated tubulin genes in Leishmania major

scientific article published on 01 May 1987

Genomics-based drug design targets the AT-rich malaria parasite: implications for antiparasite chemotherapy

scientific article published in September 2007

Glutathione S-transferase. Novel vaccine against Fasciola hepatica infection in sheep

scientific article published in December 1990

High prevalence of fasciolosis and evaluation of drug efficacy against Fasciola hepatica in dairy cattle in the Maffra and Bairnsdale districts of Gippsland, Victoria, Australia

scientific article published on 23 February 2015

Host responses during experimental infection with Fasciola gigantica and Fasciola hepatica in Merino sheep II. Development of a predictive index for Fasciola gigantica worm burden

scientific article published on 4 April 2008

Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep I. Comparative immunological and plasma biochemical changes during early infection

scientific article published on 27 October 2006

Human fasciolosis acquired in an Australian urban setting

scientific article published in March 2003

Humoral responses in mice following vaccination with DNA encoding glutathione S-transferase of Fasciola hepatica: effects of mode of vaccination and the cellular compartment of antigen expression

article

Identification of 3-hydroxyproline residues in several proteins of Fasciola hepatica

scientific article published on 01 January 1996

Identification of maxicircle DNA sequences in Leishmania Tarentolae that are homologous to sequences of specific yeast mitochondrial structural genes

scientific article published on 01 October 1982

Identification of novel diagnostic serum biomarkers for Chagas' disease in asymptomatic subjects by mass spectrometric profiling

scientific article

Identification of species, strains and clones of Leishmania by characterization of kinetoplast DNA minicircles

scientific article published in June 1984

Identification of two allelic forms of ovine CD4 exhibiting a Ser183/Pro183 polymorphism in the coding sequence of domain 3.

scientific article

Identification, expression and immunolocalization of cathepsin B3, a stage-specific antigen expressed by juvenile Fasciola gigantica.

scientific article published on 24 July 2009

Immune responses in Indonesian thin tail and Merino sheep during a primary infection with Fasciola gigantica: lack of a specific IgG2 antibody response is associated with increased resistance to infection in Indonesian sheep.

scientific article published in July 1999

Immunological approaches for the control of fasciolosis

scientific article

Inability to reproduce protection against Teladorsagia circumcincta in sheep with a purified stage-specific 31 kDa antigen complex

scientific article published on 01 January 1995

Induction of specific T-cell responses, opsonizing antibodies, and protection against Plasmodium chabaudi adami infection in mice vaccinated with genomic expression libraries expressed in targeted and secretory DNA vectors

scientific article

Induction of strain-transcending immunity against Plasmodium chabaudi adami malaria with a multiepitope DNA vaccine

scientific article published in May 2005

Inhibitory effects of chloramphenicol isomers and other antibiotics on protein synthesis and respiration in procyclic Trypanosoma brucei brucei

scientific article published on 01 February 1981

Is SELDI-TOF a valid tool for diagnostic biomarkers?

scientific article

Isolation and characterization of infective and non-infective clones of Leishmania tropica

scientific article published on 01 February 1983

Isolation, cloning, and expression of fatty-acid binding proteins from Fasciola gigantica.

scientific article

Juvenile Fasciola hepatica are resistant to killing in vitro by free radicals compared with larvae of Schistosoma mansoni.

scientific article

Leishmania major and L. donovani: a method for rapid purification of amastigotes

scientific article published on 01 October 1990

Leishmania major: expression and gene structure of the glycoprotein 63 molecule in virulent and avirulent clones and strains

scientific article published on 01 October 1990

Liver fluke vaccines in ruminants: strategies, progress and future opportunities.

scientific article published on 06 September 2014

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

scientific article

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

scientific article published on 01 November 1993

Molecular karyotype of five species of Leishmania and analysis of gene locations and chromosomal rearrangements

scientific article published on 01 October 1987

Mutations of the mitochondrial DNA of Saccharomyces cerevisiae which affect the interaction between mitochondrial ribosomes and the inner mitochondrial membrane

scientific article published on August 1978

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages

scientific article published on 01 December 1986

Peritoneal lavage cells of Indonesian thin-tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepatica

scientific article published on 8 January 2007

Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent

scientific article published in February 2008

Primary sequence heterogeneity and tissue expression of glutathione S-transferases of Fasciola hepatica

scientific article published on 01 February 1992

Production and processing of a recombinant Fasciola hepatica cathepsin B-like enzyme (FhcatB1) reveals potential processing mechanisms in the parasite.

scientific article

Protection of cattle against Fasciola hepatica infection by vaccination with glutathione S-transferase

scientific article published on 01 December 1996

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro

scientific article

Resistance and susceptibility of mice to Leishmania major: a view from Melbourne

scientific article published on September 1987

Resistance of Indonesian thin tail sheep against Fasciola gigantica and F. hepatica.

scientific article published on January 1997

Sequence of a cDNA for the ND1 gene from Leishmania major: potential uridine addition in the polyadenosine tail

scientific article published in September 1989

The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection

scientific article published on 23 March 2006

The T687G SNP in a P-glycoprotein gene of Fasciola hepatica is not associated with resistance to triclabendazole in two resistant Australian populations

scientific article published on November 2014

The developmentally regulated P100/11E gene of Leishmania major shows homology to a superfamily of reductase genes

scientific article

The evolution of enzyme specificity in Fasciola spp.

scientific article published in July 2003

The kinetoplast DNA of the hemoflagellate protozoa.

scientific article published in September 1980

The protective efficacy of MSP4/5 against lethal Plasmodium chabaudi adami challenge is dependent on the type of DNA vaccine vector and vaccination protocol

scientific article published in June 2003

The secreted cathepsin L-like proteinases of the trematode, Fasciola hepatica, contain 3-hydroxyproline residues

scientific article published on May 1994

The sensitivity and specificity of two methods for detecting Fasciola infections in cattle

scientific article published on 01 June 1999

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration.

scientific article published on 25 October 2007

Use of multiplexed tandem PCR to estimate the prevalence and intensity of Theileria orientalis infections in cattle

scientific article published on 28 February 2015

Vaccination against cutaneous leishmaniasis in mice using nonpathogenic cloned promastigotes of Leishmania major and importance of route of injection

scientific article published on 01 April 1984

Vaccination against fasciolosis by a multivalent vaccine of stage-specific antigens

scientific article

Vaccination of sheep against Fasciola hepatica with glutathione S-transferase. Identification and mapping of antibody epitopes on a three-dimensional model of the antigen

scientific article published on 01 February 1994

Vaccination with a Plasmodium chabaudi adami multivalent DNA vaccine cross-protects A/J mice against challenge with P. c. adami DK and virulent Plasmodium chabaudi chabaudi AS parasites

scientific article

Variants of a Leishmania surface antigen derived from a multigenic family

scientific article published in December 1991

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