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List of works by Margarida Fardilha

"Omics" of human sperm: profiling protein phosphatases

scientific article published on 29 July 2013

A ruthenium(II)-trithiacyclononane curcuminate complex: Synthesis, characterization, DNA-interaction, and cytotoxic activity

Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid screenings: A guide through bioinformatics tools

scientific article published on 16 May 2017

Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase

scientific article

Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception

scientific article

Amyloid precursor protein interaction network in human testis: sentinel proteins for male reproduction

scientific article

An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

scientific article published on 01 January 2018

An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model

scientific article (publication date: 2013)

Anatomy and Imaging of Rat Prostate: Practical Monitoring in Experimental Cancer-Induced Protocols

scientific article published on 30 June 2019

Applying Electron Microscopy to Characterize the Human Epididymis Collected in vivo

Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation

scientific article published on 01 January 2021

Bovine semen sexing: Sperm membrane proteomics as candidates for immunological selection of X- and Y-chromosome-bearing sperm

publication published on 26 May 2021

Can exercise training counteract doxorubicin-induced oxidative damage of testis proteome?

scientific article published on 14 August 2017

Characterisation of several ankyrin repeat protein variant 2, a phosphoprotein phosphatase 1-interacting protein, in testis and spermatozoa.

scientific article published in June 2016

Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis

scientific article published on 19 October 2020

Colocalization Analysis of PPP1 Isoforms and Two Novel Targeting Subunits in Breast Carcinoma

article published in 2008

Construction and analysis of a human testis/sperm-enriched interaction network: Unraveling the PPP1CC2 interactome

scientific article published on 29 November 2016

Contribution of the unfolded protein response to breast and prostate tissue homeostasis and its significance to cancer endocrine response

scientific article published on 01 April 2019

Differential Distribution of Alzheimer's Amyloid Precursor Protein Family Variants in Human Sperm

scientific article published on 01 January 2007

Effects of testosterone and exercise training on bone microstructure of rats

scientific article published in 2022

Evaluation of the photooxidation of galactosyl- and lactosylceramide by electrospray ionization mass spectrometry

scientific article

Exploring the effect of exercise training on testicular function

scientific article published on 08 September 2018

Exposure to mercury and human reproductive health: A systematic review

scientific article published on 01 March 2019

First Insights on the Presence of the Unfolded Protein Response in Human Spermatozoa ⬇️

scientific article published on 05 November 2019

From Proteomic Analysis to Potential Therapeutic Targets: Functional Profile of Two Lung Cancer Cell Lines, A549 and SW900, Widely Studied in Pre-Clinical Research

scientific article

Glycosphingolipids and oxidative stress: evaluation of hydroxyl radical oxidation of galactosyl and lactosylceramides using mass spectrometry

scientific article

High-intensity, high-volume exercise in addition to school exercise classes reduces endothelial progenitor cells, inflammation and catabolism in adolescent boys

scientific article published on 24 October 2019

Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform

scientific article

Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa

scientific article

Identification of a novel complex AβPP:Fe65:PP1 that regulates AβPP Thr668 phosphorylation levels.

scientific article

Identification of the human testis protein phosphatase 1 interactome

scientific article

Identification of therapeutic and diagnostic targets through yeast two hybrid system: molecular biology in medicine

scientific article published on November 1, 2012

Immunomodulatory effect of human bone marrow-derived mesenchymal stromal/stem cells on peripheral blood T cells from rheumatoid arthritis patients

scientific article published on 11 November 2019

In Vivo Interaction of the Hepatitis Delta Virus Small Antigen with the ELAV-Like Protein HuR ⬇️

scientific article published on March 24, 2011

Integration of Automatic Text Mining and Genomic and Proteomic Analysis to Unravel Prostate Cancer Biomarkers

scientific article published in 2022

Isoform-specific GSK3A activity is negatively correlated with human sperm motility

scientific article published on 01 April 2019

Lifestyle influences human sperm functional quality

Lipid remodelling in human melanoma cells in response to UVA exposure

scientific article

Modelling human prostate cancer: Rat models.

scientific article published on 20 April 2018

New Insights on the Impact of Statin Therapy in the Susceptibility to Hypovitaminosis D Through Serum Lipidome Profiling

Non-stop lab week: A real laboratory experience for life sciences postgraduate courses

scientific article

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes

scientific article (publication date: 6 November 2013)

Novel Indole-based Tambjamine-Analogues Induce Apoptotic Lung Cancer Cell Death through p38 Mitogen-Activated Protein Kinase Activation

scientific article published on 10 April 2017

Oxidative stress markers: Can they be used to evaluate human sperm quality?

scientific article published in December 2015

Physical Activity, Exercise, and Mammalian Testis Function: Emerging Preclinical Protein Biomarker and Integrative Biology Insights

scientific article published on 18 August 2015

Profiling Signaling Proteins in Sertoli Cells by Co-immunoprecipitation

scientific article published in January 2018

Profiling signaling proteins in human spermatozoa: biomarker identification for sperm quality evaluation

scientific article published on 22 July 2015

Prostate cancer: the need for biomarkers and new therapeutic targets

scientific article published on January 2014

Protein phosphatase 1 and its complexes in carcinogenesis.

scientific article published on January 2014

Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins

scientific article published on 08 July 2014

Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility

scientific article published on 20 January 2011

Protein phosphatase 1α interacting proteins in the human brain

scientific article

Protein phosphatase 1γ isoforms linked interactions in the brain

scientific article published on 19 October 2012

RanBP9 modulates AICD localization and transcriptional activity via direct interaction with Tip60.

scientific article published in January 2014

Relevance of peroxynitrite formation and 3-nitrotyrosine on spermatozoa physiology

scientific article published on 17 September 2016

SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein

scientific article published on February 2007

Sertoli Cell Preparation for Co-immunoprecipitation

scientific article published in January 2018

Signal transduction therapeutics: relevance for Alzheimer's disease

scientific article published on January 2004

Signaling mechanisms in mammalian sperm motility

scientific article published on January 2017

Signaling pathways in anchoring junctions of epithelial cells: cell-to-cell and cell-to-extracellular matrix interactions.

scientific article published on 14 July 2014

Signalling pathways involved in oocyte growth, acquisition of competence and activation

scientific article

Sodium azide and 2-deoxy-D-glucose-induced cellular stress affects phosphorylation-dependent AβPP processing

Stress response pathways in the male germ cells and gametes

scientific article published on 01 January 2020

Study on the short-term effects of increased alcohol and cigarette consumption in healthy young men's seminal quality

scientific article published on 03 April 2017

Subcellular Localization of a Novel Alternative Splicing of IIIG9 and Colocalization with PPP1gamma Isoforms

Sulfate-based lipids: Analysis of healthy human fluids and cell extracts

scientific article published on 22 March 2019

Synphilin-1A is a phosphoprotein phosphatase 1-interacting protein and affects PPP1 sorting to subcellular compartments.

scientific article published on 6 June 2014

TCTEX1D4 interactome in human testis: unraveling the function of dynein light chain in spermatozoa

scientific article published on 07 March 2014

TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network

scientific article

TGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapy

scientific article

Testicular aging: an overview of ultrastructural, cellular and molecular alterations

scientific article published on 21 April 2018

The deletion of the protein phosphatase-1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2

scientific article published in Journal of Biological Chemistry

The disruption of protein-protein interactions as a therapeutic strategy for prostate cancer

scientific article published on 16 August 2020

The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen

scientific article

The mammalian two-hybrid system as a powerful tool for high-throughput drug screening

scientific article published on 04 February 2020

The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate.

scientific article

The physiological relevance of protein phosphatase 1 and its interacting proteins to health and disease.

scientific article published on January 2010

The power of the yeast two-hybrid system in the identification of novel drug targets: building and modulating PPP1 interactomes

scientific article published on April 2015

The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis

scientific article published on 17 October 2017

Understanding fatty acid metabolism through an active learning approach

scientific article published in March 2010

Unravelling the Power of Omics for the Infertile Aging Male

scientific article published on 18 October 2016

Vias de sinalização reguladoras das funções do espermatozoide

mTOR Signaling Pathway Regulates Sperm Quality in Older Men

scientific article published on 21 June 2019

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