List of works by Pedro J. Esteves

A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits

scientific article published in March 2021

A novel functional rabbit IL-7 isoform.

scientific article

Adaptive Gene Loss? Tracing Back the Pseudogenization of the Rabbit CCL8 Chemokine

scientific article published on 15 June 2016

An Ancient, MHC-Linked, Nonclassical Class I Lineage in Cartilaginous Fish

scientific article published on 13 January 2020

An evolutionary perspective of mammal salivary peptide families: cystatins, histatins, statherin and PRPs

scientific article published on 24 January 2013

An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model

scientific article (publication date: 2013)

An overview of the lagomorph immune system and its genetic diversity

scientific article published on 23 September 2015

An update on the rabbit hemorrhagic disease virus (RHDV) strains circulating in Portugal in the 1990s: earliest detection of G3-G5 and G6.

scientific article

Analysis of substitution rates showed that TLR5 is evolving at different rates among mammalian groups

scientific article published on 02 December 2019

Apoptotic activity and Treg cells in tissue lesions of patients with leprosy

scientific article

Cartilaginous fishes offer unique insights into the evolution of the nuclear receptor gene repertoire in gnathostomes

scientific article published on 08 June 2020

Characterization of old RHDV strains by complete genome sequencing identifies a novel genetic group

scientific article published on 19 October 2017

Characterization of the T-cell receptor gamma locus and analysis of the variable gene segment expression in rabbit

scientific article

Characterization of thymosin β4 in mammals’ saliva

scientific article published on 20 December 2012

Complete coding sequences of European brown hare syndrome virus (EBHSV) strains isolated in 1982 in Sweden

scientific article published on 3 May 2013

Complete genome sequence of two rabbit hemorrhagic disease virus variant b isolates detected on the Iberian Peninsula

scientific article published on 11 January 2015

Complete genomic sequences of rabbit hemorrhagic disease virus G1 strains isolated in the European rabbit original range

scientific article published on December 2012

Computational analyses of an evolutionary arms race between mammalian immunity mediated by immunoglobulin A and its subversion by bacterial pathogens.

scientific article

Convergent evolution of IL-6 in two leporids (Oryctolagus and Pentalagus) originated an extended protein.

scientific article published on 16 July 2014

Cross-species comparison of mammalian saliva using an LC-MALDI based proteomic approach

scientific article published on 9 March 2015

Detection of RHDV strains in the Iberian hare (Lepus granatensis): earliest evidence of rabbit lagovirus cross-species infection.

scientific article

Detection of RHDVa on the Iberian Peninsula: isolation of an RHDVa strain from a Spanish rabbitry

scientific article published on 13 August 2013

Detection of positive selection in the major capsid protein VP60 of the rabbit haemorrhagic disease virus (RHDV).

scientific article

Disease-mediated bottom-up regulation: An emergent virus affects a keystone prey, and alters the dynamics of trophic webs

scientific article published on 31 October 2016

Diversity and evolutionary history of the MHC DQA gene in leporids

article

Emergence of Pathogenicity in Lagoviruses: Evolution from Pre-existing Nonpathogenic Strains or through a Species Jump?

scientific article

Endogenization of mouse mammary tumor virus (MMTV)-like elements in genomes of pikas (Ochotona sp.).

scientific article published on 4 July 2015

Epidemiology of RHDV2 (Lagovirus europaeus/GI.2) in free-living wild European rabbits in Portugal

scientific article

Evidence for recombination in the major capsid gene VP60 of the rabbit haemorrhagic disease virus (RHDV).

scientific article

Evolution and divergence of the mammalian SAMD9/SAMD9L gene family

scientific article (publication date: 12 June 2013)

Evolution of C, D and S-type cystatins in mammals: an extensive gene duplication in primates

scientific article

Evolution of CCL11: genetic characterization in lagomorphs and evidence of positive and purifying selection in mammals

scientific article

Evolution of CCL16 in Glires (Rodentia and Lagomorpha) shows an unusual random pseudogenization pattern

scientific article published on 20 February 2019

Evolution of rabbit haemorrhagic disease virus (RHDV) in the European rabbit (Oryctolagus cuniculus) from the Iberian Peninsula.

scientific article published on 21 September 2008

Evolution of viral sensing RIG-I-like receptor genes in Leporidae genera Oryctolagus, Sylvilagus, and Lepus

scientific article published on 13 November 2013

Evolutionary Insights into IL17A in Lagomorphs

scientific article

Evolutionary studies on the betaretrovirus RERV-H in the Leporidae family reveal an endogenization in the ancestor of Oryctolagus, Bunolagus and Pentalagus at 9 million years ago.

scientific article

Evolutionary study of leporid CD4 reveals a hotspot of genetic variability within the D2 domain

scientific article

Extensive gene conversion between CCR2 and CCR5 in domestic cat (Felis catus)

article

Field and experimental data indicate that the eastern cottontail (Sylvilagus floridanus) is susceptible to infection with European brown hare syndrome (EBHS) virus and not with rabbit haemorrhagic disease (RHD) virus.

scientific article

Full genome sequences are key to disclose RHDV2 emergence in the Macaronesian islands

scientific article published on 18 November 2017

Full genomic analysis of new variant rabbit hemorrhagic disease virus revealed multiple recombination events

scientific article published on 27 January 2015

Genetic Characterization of a Recombinant Myxoma Virus in the Iberian Hare (Lepus granatensis)

scientific article published on 07 June 2019

Genetic Diversity of IGHM and IGHE in the Leporids Revealed Different Patterns of Diversity in the Two European Rabbit Subspecies (O. cuniculus algirus and O. c. cuniculus)

scientific article published on 12 November 2019

Genetic analysis and mapping of biochemical markers in an F2 intercross of two inbred strains of the rabbit (Oryctolagus cuniculus)

article

Genetic characterization of CCL3, CCL4 and CCL5 in leporid genera Oryctolagus, Sylvilagus and Lepus

scientific article published on 19 September 2013

Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs.

scientific article published on 21 September 2015

Genetic characterization of the chemokine receptor CXCR4 gene in lagomorphs: comparison between the families Ochotonidae and Leporidae

article

Genetic diversity at the hinge region of the unique immunoglobulin heavy gamma (IGHG) gene in leporids (Oryctolagus, Sylvilagus and Lepus)

scientific article published on 01 June 2006

Genetic diversity comparison of the DQA gene in European rabbit (Oryctolagus cuniculus) populations

scientific article published on 26 August 2015

Genetic variation at chemokine receptor CCR5 in leporids: alteration at the 2nd extracellular domain by gene conversion with CCR2 in Oryctolagus, but not in Sylvilagus and Lepus species

scientific article published on 5 April 2006

Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner

scientific article

Host specific glycans are correlated with susceptibility to infection by lagoviruses, but not with their virulence.

scientific article published on 29 November 2017

Hotspot variation at the CH2-CH3 interface of leporid IgG antibodies (Oryctolagus, Sylvilagus and Lepus).

scientific article published in December 2002

ICTV Virus Taxonomy Profile: Caliciviridae

scientific article published on 01 November 2019

Identification of a Novel Myxoma Virus C7-Like Host Range Factor That Enabled a Species Leap from Rabbits to Hares

scientific article published on 30 March 2022

Insights into the European rabbit (Oryctolagus cuniculus) innate immune system: genetic diversity of the toll-like receptor 3 (TLR3) in wild populations and domestic breeds

scientific article published on 21 August 2013

Is the new variant RHDV replacing genogroup 1 in Portuguese wild rabbit populations?

scientific article

Leporid immunoglobulin G shows evidence of strong selective pressure on the hinge and CH3 domains

scientific article

Levels and Patterns of Genetic Diversity and Population Structure in Domestic Rabbits

scientific article published on 21 December 2015

Maximum-likelihood approaches reveal signatures of positive selection in IL genes in mammals

scientific article published on 17 June 2013

Mitochondrial retrograde signaling mediated by UCP2 inhibits cancer cell proliferation and tumorigenesis

scientific article

Molecular epidemiology of Rabbit Haemorrhagic Disease Virus in Australia: when one became many

scientific article

Molecular evolution and antigenic variation of European brown hare syndrome virus (EBHSV).

scientific article

Neofunctionalization of the Sec1 α1,2fucosyltransferase paralogue in leporids contributes to glycan polymorphism and resistance to rabbit hemorrhagic disease virus

scientific article

New variant of rabbit hemorrhagic disease virus, Portugal, 2012-2013.

scientific article published on November 2013

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes

scientific article (publication date: 6 November 2013)

Not so unique to Primates: The independent adaptive evolution of TRIM5 in Lagomorpha lineage

scientific article published on 12 December 2019

Not-So-Novel Michigan Rabbit Calicivirus1

scientific article published on August 1, 2010

Overcoming species barriers: an outbreak of Lagovirus europaeus GI.2/RHDV2 in an isolated population of mountain hares (Lepus timidus)

scientific article published on 26 November 2018

Parallel adaptation of rabbit populations to myxoma virus

scientific article published on 14 February 2019

Partial sequencing of recent Portuguese myxoma virus field isolates exhibits a high degree of genetic stability.

scientific article published on 8 August 2009

Positive evolutionary selection on the RIG-I-like receptor genes in mammals

scientific article

Proposal for a unified classification system and nomenclature of lagoviruses

scientific article

Pseudogenization of CCL14 in the Ochotonidae (pika) family

scientific article published on 26 March 2015

Pseudogenization of the MCP-2/CCL8 chemokine gene in European rabbit (genus Oryctolagus), but not in species of Cottontail rabbit (Sylvilagus) and Hare (Lepus).

scientific article

Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a review

scientific article (publication date: 10 February 2012)

Rabbit hemorrhagic disease virus detected in Pico, Azores, Portugal, revealed a unique endemic strain with more than 17 years of independent evolution

scientific article

Rabbit models of human diseases for diagnostics and therapeutics development

article

Recombination between G2 and G6 strains of rabbit hemorrhagic disease virus (RHDV) in China

scientific article

Recurrent introgression of mitochondrial DNA among hares (Lepus spp.) revealed by species-tree inference and coalescent simulations.

scientific article

Restriction fragment alleles of the rabbit IGHG genes with reference to the rabbit IGHGCH2 or e locus polymorphism

article

Sequencing of Sylvilagus VDJ genes reveals a new VHa allelic lineage and shows that ancient VH lineages were retained differently in leporids

scientific article published on 30 September 2014

Sequencing of VDJ genes in Lepus americanus confirms a correlation between VHn expression and the leporid species continent of origin

scientific article published on 04 June 2019

Sequencing of modern Lepus VDJ genes shows that the usage of VHn genes has been retained in both Oryctolagus and Lepus that diverged 12 million years ago.

scientific article published on 24 August 2013

Sharing of endogenous lentiviral gene fragments among leporid lineages separated for more than 12 million years

scientific article (publication date: March 2009)

Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

scientific article

Spread of new variant RHDV in domestic rabbits on the Iberian Peninsula

scientific article published on 31 December 2013

Study of Sylvilagus rabbit TRIM5α species-specific domain: how ancient endoviruses could have shaped the antiviral repertoire in Lagomorpha

scientific article

Survey of genetic diversity of IgG in wild and domestic rabbits

scientific article published on 29 July 2015

TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network

scientific article

The evolution of S100A7 in primates: a model of concerted and birth-and-death evolution

scientific article published on 29 August 2018

The evolution of the immunoglobulin heavy chain variable region (IgVH) in Leporids: an unusual case of transspecies polymorphism

scientific article published on 25 October 2005

The phylogeny of pikas (Ochotona) inferred from a multilocus coalescent approach

scientific article published on 28 January 2015

The remnant of the European rabbit (Oryctolagus cuniculus) IgD gene

scientific article published on 23 August 2017

The wide utility of rabbits as models of human diseases.

scientific article published on 22 May 2018

Tracking the evolution of the G1/RHDVb recombinant strains introduced from the Iberian Peninsula to the Azores islands, Portugal.

scientific article published on 9 July 2015

Trichomonas Infection in a Community of Free-Ranging Domestic and Wild Columbiformes and Bonelli's Eagle (Aquila fasciata).

scientific article

Widespread gene conversion of alpha-2-fucosyltransferase genes in mammals

scientific article published on 16 June 2009