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List of works by James M O'Donnell

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness

scientific article published on 10 March 2017

Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice.

scientific article published on 2 November 2011

Animal models of depression and neuroplasticity: assessing drug action in relation to behavior and neurogenesis

scientific article published on January 2012

Antagonism of the antidepressant-like effects of clenbuterol by central administration of beta-adrenergic antagonists in rats

scientific article published on 25 July 2003

Antidepressant effects assessed using behavior maintained under a differential-reinforcement-of-low-rate (DRL) operant schedule.

scientific article

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4).

scientific article published on March 2004

Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus

scientific article published on 10 June 2009

Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function

scientific article published on 3 September 2003

Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences

scientific article

Antidepressant-like effects of PDE4 inhibitors mediated by the high-affinity rolipram binding state (HARBS) of the phosphodiesterase-4 enzyme (PDE4) in rats

scientific article

Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme

scientific article published in October 2002

Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).

scientific article published on 15 August 2007

Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling

scientific article published on 14 August 2009

Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs

scientific article published on 15 October 2008

Blockade of autoreceptor-mediated inhibition of norepinephrine release by atipamezole is maintained after chronic reuptake inhibition

scientific article published on 15 August 2007

Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures

scientific article published on 12 March 2007

Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum

scientific article

Curcumin prevents corticosterone-induced neurotoxicity and abnormalities of neuroplasticity via 5-HT receptor pathway

scientific article published on 18 July 2011

Dual inhibitors of phosphodiesterase-4 and serotonin reuptake

scientific article published on March 2009

Effects of antidepressants in rats trained to discriminate centrally administered isoproterenol

scientific article

Effects of repeated treatment with phosphodiesterase-4 inhibitors on cAMP signaling, hippocampal cell proliferation, and behavior in the forced-swim test

journal article published in 2011

Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats

scientific article published on 26 January 2005

Evidence for global reduction in brain cyclic adenosine monophosphate signaling in depression

scientific article published in October 2012

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

scientific article

Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus

scientific article (publication date: July 2002)

Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus

scientific article

Inhibitor binding to type 4 phosphodiesterase (PDE4) assessed using [3H]piclamilast and [3H]rolipram

scientific article published in May 2003

Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats

scientific article

Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

scientific article published on 14 August 2018

Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine

scientific article published on 16 April 2008

Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes

scientific article

Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway

scientific article

Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling

scientific article published on January 2011

Phosphodiesterases in the central nervous system: implications in mood and cognitive disorders

scientific article published on January 2011

Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior

scientific article published on 15 October 2008

RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects.

scientific article published on February 2013

Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram

scientific article

Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice.

scientific article

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