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List of works by Bernard L. Schneider

A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity

scientific article

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells.

scientific article published on 5 October 2013

A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.

scientific article published in January 2011

A self-immunomodulating myoblast cell line for erythropoietin delivery

scientific article

A subcutaneous cellular implant for passive immunization against amyloid-β reduces brain amyloid and tau pathologies.

scientific article published on 8 March 2016

Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.

scientific article published on 28 February 2015

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

scientific article published on 03 July 2019

Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL.

scientific article published on 12 August 2017

Amyloid-β plaque deposition measured using propagation-based X-ray phase contrast CT imaging.

scientific article

An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker

scientific article published on 18 June 2012

Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent

scientific article published on 27 July 2016

Behaviour-dependent recruitment of long-range projection neurons in somatosensory cortex

scientific article published on 23 June 2013

Cellular implants: pioneers in xenotransplantation?

scientific article

Channel-mediated lactate release by K⁺-stimulated astrocytes

scientific article published in March 2015

Chondroitinase gene therapy improves upper limb function following cervical contusion injury

scientific article published on June 2015

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

scientific journal article

Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion

scientific article published on 19 March 2018

Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia.

scientific article published in October 2002

Direct and Retrograde Transduction of Nigral Neurons with AAV6, 8, and 9 and Intraneuronal Persistence of Viral Particles ⬇️

scientific article published on June 1, 2013

Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6.

scientific article published on 3 September 2009

Encapsulated cellular implants for recombinant protein delivery and therapeutic modulation of the immune system.

scientific article published on 8 May 2015

Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?

scientific article

Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo

scientific article

FOXO3 determines the accumulation of α-synuclein and controls the fate of dopaminergic neurons in the substantia nigra.

scientific article published on 24 October 2013

Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model

scientific article published on 25 December 2012

Gene Therapy: A Promising Approach for Neuroprotection in Parkinson's Disease?

scientific article published on 20 December 2016

Genetic engineering of cell lines using lentiviral vectors to achieve antibody secretion following encapsulated implantation

scientific article published on January 2014

Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates

scientific article published on March 2006

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.

scientific article published on 18 November 2015

In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system

scientific article published in November 2017

Inducing Tolerance to a Soluble Foreign Antigen by Encapsulated Cell Transplants

article

Intracerebroventricular injection of adeno-associated virus 6 and 9 vectors for cell type-specific transgene expression in the spinal cord

scientific article published on 15 January 2014

Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury

scientific article published on April 2014

Lentiviral Vectors for the Engineering of Implantable Cells Secreting Recombinant Antibodies

scientific article published in January 2016

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

scholarly article

Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy

scientific article published on 3 March 2007

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

scientific article published on 9 August 2011

Long-range connectivity of mouse primary somatosensory barrel cortex

scientific article published on 09 June 2010

Long-term doxycycline-regulated secretion of erythropoietin by encapsulated myoblasts

scientific article

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.

scientific article

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS.

scientific article published on 5 January 2015

Measurement of autophagy flux in the nervous system in vivo

scientific article

Mimicking phosphorylation at serine 87 inhibits the aggregation of human α-synuclein and protects against its toxicity in a rat model of Parkinson's disease.

scientific article published in February 2012

Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects

scientific article published on 19 October 2017

Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson's disease

scientific article published on 09 July 2020

Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice

scientific article published on 23 November 2010

Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity.

scientific article published on 24 February 2012

Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation

scientific article

Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity

scientific article published on 9 January 2013

Overview of mouse models of Parkinson's disease

scientific article published on 3 September 2014

PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein

scientific article

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

scientific article published on 07 May 2018

Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons

scientific article published on 4 January 2017

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

scientific article

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

scientific article published on 22 June 2015

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

scientific article

Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions

scientific article

Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease

scientific article

Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

scientific article

Prevention of the initial host immuno-inflammatory response determines the long-term survival of encapsulated myoblasts genetically engineered for erythropoietin delivery

scientific article published in April 2003

Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer's disease

scientific article published in January 2012

Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease

scientific article

Recovery of walking after paralysis by regenerating characterized neurons to their natural target region

scientific article published on 21 September 2023

Regulation of Memory Formation by the Transcription Factor XBP1.

scientific article

SOD1 silencing in motoneurons or glia rescues neuromuscular function in ALS mice.

scientific article

Spinal cord stimulation improves forelimb use in an alpha-synuclein animal model of Parkinson's disease.

scientific article published on 8 February 2016

Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions.

scientific article published in July 2004

Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.

scientific article published on 12 January 2012

Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice.

scientific article published on 15 April 2008

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

scientific article

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain

scientific article

Tmc gene therapy restores auditory function in deaf mice

scientific article

Transient striatal delivery of GDNF via encapsulated cells leads to sustained behavioral improvement in a bilateral model of Parkinson disease

scientific article published on 21 November 2005

Un implant bioactif pour prévenir la maladie d’Alzheimer

scientific article published on 25 January 2017

Using human neural stem cells to model neurological disease.

scientific article published on February 2004

Viral vectors, animal models and new therapies for Parkinson's disease

scientific article published on 27 June 2008

Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease

scientific article published in February 2004

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

scientific article

Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease

scientific article

α-Synuclein increases β-amyloid secretion by promoting β-/γ-secretase processing of APP.

scientific article

α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).

scientific article

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