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Authors whose works are in public domain in at least one jurisdiction

List of works by Helle S. Waagepetersen

1-50 of 143 results

The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

scientific article

The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

scientific article published on 01 November 2007

Glutamate metabolism in the brain focusing on astrocytes.

scientific article published in January 2014

Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter.

scientific article published in January 2005

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA

scientific article published on August 15, 2013

Comparison of lactate and glucose metabolism in cultured neocortical neurons and astrocytes using 13C-NMR spectroscopy

scientific article published in January 1998

Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

scientific article published in February 2006

Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level

scientific article published on 2 March 2012

Functional significance of brain glycogen in sustaining glutamatergic neurotransmission.

scientific article

Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents

scientific article

Glutamine in the central nervous system: function and dysfunction.

scientific article

Primary cultures of astrocytes: their value in understanding astrocytes in health and disease.

scientific article published on 28 August 2012

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission.

scientific article published on September 2004

The glutamine-glutamate/GABA cycle: function, regional differences in glutamate and GABA production and effects of interference with GABA metabolism.

scientific article

Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels.

scientific article published in May 2009

Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes

scientific article published in September 2001

Compartmentation of Glutamine, Glutamate, and GABA Metabolism in Neurons and Astrocytes: Functional Implications

scientific article published on October 1, 2003

Low cerebral oxygen consumption and blood flow in patients with cirrhosis and an acute episode of hepatic encephalopathy

scientific article

Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes

scientific article

Demonstration of pyruvate recycling in primary cultures of neocortical astrocytes but not in neurons

scientific article

Role of glutamine and neuronal glutamate uptake in glutamate homeostasis and synthesis during vesicular release in cultured glutamatergic neurons

scientific article published in July 2005

Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

scientific article published on 24 January 2014

Comparison of effects of DL-threo-beta-benzyloxyaspartate (DL-TBOA) and L-trans-pyrrolidine-2,4-dicarboxylate (t-2,4-PDC) on uptake and release of [3h]D-aspartate in astrocytes and glutamatergic neurons

scientific article published in June 2001

Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis.

scientific article published on 28 April 2010

Elucidation of the quantitative significance of pyruvate carboxylation in cultured cerebellar neurons and astrocytes

scientific article published in December 2001

Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model

scientific article published on 5 January 2012

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission

scientific article published on 28 September 2012

Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

scientific article published on 24 January 2008

Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake.

scientific article

Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

scientific article published in December 2001

In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate

scientific article published on 5 March 2012

Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function

scientific article published on 23 April 2015

Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

scientific article published on 27 April 2012

The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

scientific article published on 06 February 2007

Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes

scientific article published on 29 July 2015

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

scientific article published on 15 September 2016

Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase

scientific article

Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

scientific article published on 18 May 2010

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

scientific article published on 30 September 2015

GABA: homeostatic and pharmacological aspects

scientific article

Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons.

scientific article published on 5 April 2012

Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

scientific article published on December 2007

Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source

scientific article published on 14 September 2011

Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

scientific article

Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures.

scientific article published in January 2005

The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism

scientific article

siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate

scientific article

Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix

scientific article published on 01 September 2007

Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

scientific article published on 07 April 2011

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

scientific article published on 02 June 2011