List of works - Michael Lazarou

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease

article

Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis

scientific article published on 24 February 2007

Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I

scientific article

Assembly of mitochondrial complex I and defects in disease

scientific article published on 04 May 2008

Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria

scientific article published on 16 October 2009

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis

scientific article published on 26 July 2013

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

scientific article

Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

scientific article published on 12 August 2020

Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs

scientific article published on 6 February 2017

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.

scientific article published on 11 December 2017

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

scientific article published in February 2018

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

scientific article

Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits

scientific article published in January 2009

Cost of a naturally occurring two-amino acid deletion in cytochrome c oxidase subunit 7A in Drosophila simulans.

scientific article published in October 2010

Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller

scientific article

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

scientific article

Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease

scientific article

Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography

article

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor

scientific article

Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5

scientific article published on 05 March 2021

Keeping the immune system in check: a role for mitophagy

scientific article

LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy

scientific article published in Nature Communications

Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

scientific article published on 03 August 2020

Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs

scientific article published on 18 October 2019

Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB

scientific article published on 19 October 2020

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

scientific article (publication date: 29 November 2010)

Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients

scientific article

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1

scientific article

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

scientific article

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

scientific article (publication date: 28 April 2014)

Parkin and mitophagy in cancer.

scientific article

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy

scientific article published on 20 December 2018

Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation

scientific article published on 23 November 2020

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin

scientific article published on 25 January 2012

Sequestration and autophagy of mitochondria do not cut proteins across the board

scientific article published on 8 April 2013

Structure, function, and regulation of mitofusin-2 in health and disease

scientific article

The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.

scientific article published on 13 September 2016

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

scientific article published on 12 August 2015

Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy

scientific journal article

YoungMito 2018: Report on the 1st International Mitochondria Meeting for Young Scientists

scientific article published on 01 October 2018

List of works by Michael Lazarou

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease

Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis

Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I

Assembly of mitochondrial complex I and defects in disease

Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits

Cost of a naturally occurring two-amino acid deletion in cytochrome c oxidase subunit 7A in Drosophila simulans.

Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease

Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor

Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5

Keeping the immune system in check: a role for mitophagy

LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy

Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens

Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs

Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Parkin and mitophagy in cancer.

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy

Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin

Sequestration and autophagy of mitochondria do not cut proteins across the board

Structure, function, and regulation of mitofusin-2 in health and disease

The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy

YoungMito 2018: Report on the 1st International Mitochondria Meeting for Young Scientists